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Invitrogen
DNAJC10 Polyclonal Antibody
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FIGURE: 1 / 1
DNAJC10 Antibody (PA5-88451) in WB
Western blot analysis of DNAJC10 in extracts of various cell lines. Samples were incubated with DNAJC10 Polyclonal antibody (Product # PA5-88451) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-88451
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 614-793 of human DNAJC10 (NP_0618541)
Conjugate
Form
Liquid
Concentration
0.12 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804924
Product Specific Information
Immunogen sequence: IDCQQYHSFC AQENVQRYPE IRFFPPKSNK AYHYHSYNGW NRDAYSLRIW GLGFLPQVST DLTPQTFSEK VLQGKNHWVI DFYAPWCGPC QNFAPEFELL ARMIKGKVKA GKVDCQAYAQ TCQKAGIRAY PTVKFYFYER AKRNFQEEQI NTRDAKAIAA LISEKLETLR NQGKRNKDEL; Positive Samples: U-87MG, HT-29, SK-OV-3, Raji, SGC-7901, Mouse pancreas, Mouse Lung; Cellular Location: Endoplasmic reticulum lumen
Target Information
This endoplasmic reticulum co-chaperone may play a role in protein folding and translocation across the endoplasmic reticulum membrane. DNAJC10 may act as a co-chaperone for HSPA5.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DnaJ (Hsp40) homolog, subfamily C, member 10; DnaJ homolog subfamily C member 10; Endoplasmic reticulum DNA J domain-containing protein 5; Endoplasmic reticulum DnaJ-PDI fusion protein 1; ER-resident protein ERdj5; J domain-containing PDI-like protein; J domain-containing protein disulfide isomerase-like protein; J-domain-containing protein disulfide isomerase-like protein; Macrothioredoxin; MTHr; protein disulfide isomerase family A, member 19
Gene Aliases: 1200006L06Rik; D2Ertd706e; DNAJC10; ERDJ5; JPDI; MTHr; PDIA19; UNQ495/PRO1012
UniProt ID: (Human) Q8IXB1, (Rat) Q498R3, (Mouse) Q9DC23
Entrez Gene ID: (Human) 54431, (Rat) 295690, (Mouse) 66861
ATPase activator activity
protein binding
protein disulfide oxidoreductase activity
disulfide oxidoreductase activity
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Hsp70 protein binding
chaperone binding
ATPase binding
misfolded protein binding
peptide-methionine (S)-S-oxide reductase activity
oxidoreductase activity
peptide-methionine (R)-S-oxide reductase activity
methionine-R-sulfoxide reductase activity
negative regulation of protein phosphorylation
ER-associated ubiquitin-dependent protein catabolic process
positive regulation of ATPase activity
protein folding in endoplasmic reticulum
response to endoplasmic reticulum stress
cell redox homeostasis
oxidation-reduction process
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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