Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
DNAJC2/MPP11 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
11971-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DNAJC2/MPP11 Fusion Protein Ag2594 (1-167 aa encoded by BC056682)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLLLPSAAD GRGTAITHAL TSASTLCQVE PVGRWFEAFV KRRNRNASAS FQELEDKKEL SEESEDEELQ LEEFPMLKTL DPKDWKNQDH YAVLGLGHVR YKATQRQIKA AHKAMVLKHH PDKRKAAGEP IKEGDNDYFT CITKGSPGDS YQKLILQLIH LMKCYLIQ (1-167 aa encoded by BC056682)
Target Information
EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: (rat homolog) mouse id-associated protein 1; DnaJ (Hsp40) homolog, subfamily C, member 2; DnaJ homolog subfamily C member 2; Gliosarcoma-related antigen MIDA1; Id associate 1; M-phase phosphoprotein 11; MIDA1; Mouse Id associate 1; zuotin related factor 1; zuotin related factor 2; Zuotin-related factor 1
Gene Aliases: AU020218; DNAJC2; MIDA1; MPHOSPH11; MPP11; ZRF1; Zrf2; ZUO1
UniProt ID: (Human) Q99543, (Rat) Q7TQ20, (Mouse) P54103
Entrez Gene ID: (Human) 27000, (Rat) 116456, (Mouse) 22791
DNA replication
transcription, DNA-templated
chromatin modification
negative regulation of cell growth
positive regulation of transcription, DNA-templated
negative regulation of DNA biosynthetic process
regulation of transcription, DNA-templated
covalent chromatin modification
positive regulation of ATPase activity
'de novo' cotranslational protein folding
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support