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DNAJC7 Polyclonal Antibody

DNAJC7 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

DNAJC7 Antibody (11090-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using DNAJC7 antibody 11090-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

DNAJC7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DNAJC7 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

11090-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DNAJC7 Fusion Protein Ag1572 (145-494 aa encoded by BC011837)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: YEKIAETDF EKRDFRKVVF CMDRALEFAP ACHRFKILKA ECLAMLGRYP EAQSVASDIL RMDSTNADAL YVRGLCLYYE DCIEKAVQFF VQALRMAPDH EKACIACRNA KALKAKKEDG NKAFKEGNYK LAYELYTEAL GIDPNNIKTN AKLYCNRGTV NSKLRKLDDA IEDCTNAVKL DDTYIKAYLR RAQCYMDTEQ YEEAVRDYEK VYQTEKTKEH KQLLKNAQLE LKKSKRKDYY KILGVDKNAS EDEIKKAYRK RALMHHPDRH SGASAEVQKE EEKKFKEVGE AFTILSDPKK KTRYDSGQDL DEEGMNMGDF DPNNIFKAFF GGPGGFSFEA SGPGNFFFQF G (145-494 aa encoded by BC011837)

Target Information

DNAJC7 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 ).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

DnaJC7 specifically regulates tau seeding.

bioRxiv : the preprint server for biology

Perez VA,Sanders DW,Mendoza-Oliva A,Stopschinski BE,Mullapudi V,White CL,Joachimiak LA,Diamond MI

Thu Mar 16 00:00:00 UTC 2023

ALS-linked loss of Cyclin-F function affects HSP90.

Life science alliance

Siebert A,Gattringer V,Weishaupt JH,Behrends C

Fri Sep 16 00:00:00 UTC 2022

Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin.

Cancers

Alalem M,Bhosale M,Ranjan A,Yamamoto S,Kaida A,Nishikawa S,Parrales A,Farooki S,Anant S,Padhye S,Iwakuma T

Mon Aug 29 00:00:00 UTC 2022

DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation.

Nature communications

Hou Z,Wydorski PM,Perez VA,Mendoza-Oliva A,Ryder BD,Mirbaha H,Kashmer O,Joachimiak LA

Thu Sep 09 00:00:00 UTC 2021

Indirect activation of constitutive androstane receptor in three-dimensionally cultured HepG2 cells.

Biochemical pharmacology

Yokobori K,Azuma I,Chiba K,Akita H,Furihata T,Kobayashi K

Tue Oct 01 00:00:00 UTC 2019

Indirect activation of constitutive androstane receptor in three-dimensionally cultured HepG2 cells.

Biochemical pharmacology

Yokobori K,Azuma I,Chiba K,Akita H,Furihata T,Kobayashi K

Tue Oct 01 00:00:00 UTC 2019

Co-chaperon DnaJC7/TPR2 enhances p53 stability and activity through blocking the complex formation between p53 and MDM2.

Biochemical and biophysical research communications

Kubo N,Wu D,Yoshihara Y,Sang M,Nakagawara A,Ozaki T

Fri Jan 18 00:00:00 UTC 2013

Co-chaperon DnaJC7/TPR2 enhances p53 stability and activity through blocking the complex formation between p53 and MDM2.

Biochemical and biophysical research communications

Kubo N,Wu D,Yoshihara Y,Sang M,Nakagawara A,Ozaki T

Fri Jan 18 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: CCRP; Cytoplasmic CAR retention protein; DnaJ (Hsp40) homolog, subfamily C, member 7; DnaJ homolog subfamily C member 7; MDj11; tetratricopeptide repeat domain 2; Tetratricopeptide repeat protein 2; TPR repeat protein 2

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Gene Aliases: 2010003F24Rik; 2010004G07Rik; CCRP; DJ11; DJC7; DNAJC7; mDj11; mTpr2; TPR2; TTC2

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UniProt ID: (Human) Q99615, (Mouse) Q9QYI3

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Entrez Gene ID: (Human) 7266, (Mouse) 56354

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Function(s)

ATPase activator activity protein binding heat shock protein binding

Process(es)

protein folding positive regulation of ATPase activity chaperone cofactor-dependent protein refolding regulation of cellular response to heat

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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DNAJC7 Polyclonal Antibody

DNAJC7 Antibody (11090-1-AP) in ICC/IF

Product Details

11090-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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