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Peptide sequence: MVTANKAHTG QGSCWVATLA SAMIPPADSL LKYDTPVLVS RNTEKRSPKA
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Axonemal dynein light intermediate polypeptide 1; dJ423B22.5 (axonemal dynein light chain (hp28)); dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; hp28; Inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas
Gene Aliases: dJ423B22.5; DNALI1; hp28; P28
UniProt ID: (Human) O14645
Entrez Gene ID: (Human) 7802
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