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Invitrogen
DNASE2B Polyclonal Antibody
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Product Details
PA5-100482
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DNASE2B(Accession Q8WZ79), corresponding to amino acid residues Y302-G352.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2849992
Product Specific Information
Antibody detects endogenous levels of total DNASE2B.
Target Information
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deoxyribonuclease DLAD; Deoxyribonuclease II beta; Deoxyribonuclease-2-beta; DNA for uricase; DNase II beta; DNase II-like acid DNase; DNase2-like acid DNase; DNaseII-like acid DNase; Endonuclease DLAD; lysosomal DNase II
Gene Aliases: DLAD; DNASE2B; UOX
UniProt ID: (Human) Q8WZ79, (Rat) Q9QZK9
Entrez Gene ID: (Human) 58511, (Rat) 59296
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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