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Bioss
DNase 2 alpha Polyclonal Antibody
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FIGURE: 1 / 5
DNase 2 alpha Antibody (BS-7652R) in IHC (P)
Human colon cancer 4% Paraformaldehyde-fixed and paraffin-embedded. Antigen retrieval: Citrate buffer ( 0.01 M, pH 6.0 ) boiling bath for 15 min; Blocking buffer (normal goat serum 10%) at 37°C for 20 min; Incubation: Anti-DNase II Polyclonal Antibody, Unconjugated(bs-7652R) 1:200, Overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 mi... View More
Product Details
BS-7652R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DNase II alpha, amino acids 25-90.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acid DNase; deoxyribonuclease; Deoxyribonuclease II alpha; Deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; Lysosomal DNase II; R31240_2
Gene Aliases: DNASE2; DNASE2A; DNL; DNL2
UniProt ID: (Human) O00115, (Rat) Q9QZK8
Entrez Gene ID: (Human) 1777, (Rat) 171575
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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