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Invitrogen
DOK4 Polyclonal Antibody
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Product Details
PA5-63190
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DOK4. Recombinant protein control fragment (Product #RP-101658).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640745
Product Specific Information
Immunogen sequence: QRLEKYPDEK SVCLRGCPKV TEISNVKCVT RLPKETKRQA VAIIFTDDSA RTFTCDSEL
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Docking protein 4; Downstream of tyrosine kinase 4; Insulin receptor substrate 5; IRS-5
Gene Aliases: DOK4; IRS-5; IRS5
UniProt ID: (Human) Q8TEW6
Entrez Gene ID: (Human) 55715
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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