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Immunogen sequence: LLQSVKNSML QMKMSERAAS LSTMVPLPRS AYWQHITRQH STGQLYRLQD VSSPLKLHRT ETFPAYRSEH; Positive Samples: Mouse kidney, Mouse liver, Rat skeletal muscle
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Docking protein 5; Downstream of tyrosine kinase 5; MGC16926; Protein dok-5
Gene Aliases: 2700055C10Rik; Dok5; RGD1562846
UniProt ID: (Mouse) Q91ZM9
Entrez Gene ID: (Mouse) 76829, (Rat) 502694
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