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Invitrogen
DOPA Decarboxylase Polyclonal Antibody
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FIGURE: 1 / 6
DOPA Decarboxylase Antibody (PA5-47512) in ICC/IF
Immunocytochemistry analysis of DOPA Decarboxylase in immersion fixed IMR‚32 human neuroblastoma cell line. Samples were incubated in DOPA Decarboxylase polyclonal antibody (Product # PA5-47512) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to ... View More
Product Details
PA5-47512
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant human Dopa Decarboxylase/DDC Met1-Glu480
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609231
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AADC; aromatic L-amino acid decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719; L-Dopa decarboxylase
Gene Aliases: AADC; DDC
UniProt ID: (Human) P20711, (Mouse) O88533, (Rat) P14173
Entrez Gene ID: (Human) 1644, (Mouse) 13195, (Rat) 24311
cellular amino acid metabolic process
response to toxic substance
aminergic neurotransmitter loading into synaptic vesicle
carboxylic acid metabolic process
dopamine biosynthetic process
catecholamine biosynthetic process
serotonin biosynthetic process
circadian rhythm
multicellular organism aging
isoquinoline alkaloid metabolic process
cellular response to drug
dopamine metabolic process
response to pyrethroid
phytoalexin metabolic process
cellular response to alkaloid
cellular response to growth factor stimulus
indolalkylamine biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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