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Recommended positive controls: HeLa.
Predicted reactivity: Mouse (80%), Rat (82%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Diphthamide biosynthesis protein 2; diphthamide biosynthesis protein 2 homolog-like 2; diphthamide biosynthesis-like protein 2; Diphtheria toxin resistance protein 2; diptheria toxin resistance protein required for diphthamide biosynthesis-like 2; DPH2-like 2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2
Gene Aliases: DPH2; DPH2L2
UniProt ID: (Human) Q9BQC3
Entrez Gene ID: (Human) 1802
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