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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Diphthamide biosynthesis protein 2; diphthamide biosynthesis protein 2 homolog-like 2; diphthamide biosynthesis-like protein 2; Diphtheria toxin resistance protein 2; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1; diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2; diptheria toxin resistance protein required for diphthamide biosynthesis-like 2; DPH2-like 2; MmDph2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase DPH2
Gene Aliases: 9130020C19Rik; AI467389; DPH2; DPH2L2
UniProt ID: (Human) Q9BQC3, (Rat) Q568Y2, (Mouse) Q9CR25
Entrez Gene ID: (Dog) 475387, (Human) 1802, (Rat) 298452, (Mouse) 67728
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