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FIGURE: 1 / 1
DPH5 Antibody (H00051611-B01P) in WB
Western Blot analysis of DPH5 expression in transfected 293T cell line (H00051611-T01) by DPH5 MaxPab polyclonal antibody.
Lane 1: DPH5 transfected lysate(31.35 KDa).
Lane 2: Non-transfected lysate.
Lane 1: DPH5 transfected lysate(31.35 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00051611-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DPH5 (NP_001070862.1, 1 a.a. approximately 285 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MLYLIGLGLG DAKDITVKGL EVVRRCSRVY LEAYTSVLTV GKEALEEFYG RKLVVADREE VEQEADNILK DADISDVAFL VVGDPFGATT HSDLVLRATK LGIPYRVIHN ASIMNAVGCC GLQLYKFGET VSIVFWTDTW RPESFFDKVK KNRQNGMHTL CLLDIKVKEQ SLENLIKGRK IYEPPRYMSV NQAAQQLLEI VQNQRIRGEE PAVTEETLCV GLARVGADDQ KIAAGTLRQM CTVDLGEPLH SLIITGGSIH PMEMEMLSLF SIPENSSESQ SINGL
Target Information
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Diphthamide biosynthesis methyltransferase; Diphthine methyl ester synthase; diphthine synthase; DPH5 homolog; protein x 0011
Gene Aliases: AD-018; CGI-30; DPH5; HSPC143; NPD015
UniProt ID: (Human) Q9H2P9
Entrez Gene ID: (Human) 51611
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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