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As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dosage compensation-related protein DPY30; dpy-30 histone methyltransferase complex regulatory subunit; dpy-30 homolog; Dpy-30-like protein; Dpy-30L; Protein dpy-30 homolog
Gene Aliases: 2810410M20Rik; C87842; Cps25; DPY30; HDPY-30; Saf19
UniProt ID: (Human) Q9C005, (Mouse) Q99LT0
Entrez Gene ID: (Human) 84661, (Mouse) 66310
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