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Immunogen sequence: TISRGKVVYE AGVFSVTAGD GKFIPRKPFA EYIYKRIKQR DRTCTPTPVE RAPYKGEVAT LKSRVTKEDA TAG
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 82%.
Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DHP; Dihydropyrimidinase; Dihydropyrimidine amidohydrolase; Hydantoinase
Gene Aliases: DHP; DHPase; DPYS
UniProt ID: (Human) Q14117
Entrez Gene ID: (Human) 1807
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