Proteintech

DRG2 Polyclonal Antibody

DRG2 Antibody in Immunocytochemistry (ICC/IF)

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DRG2 Antibody (14743-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol) fixed HepG2 cells using 14743-1-AP (DRG2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

DRG2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DRG2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

14743-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:3000-1:8000

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DRG2 Fusion Protein Ag6433 (1-364 aa encoded by BC000493)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.24 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGILEKISE IEKEIARTQK NKATEYHLGL LKAKLAKYRA QLLEPSKSAS SKGEGFDVMK SGDARVALIG FPSVGKSTFL SLMTSTASEA ASYEFTTLTC IPGVIEYKGA NIQLLDLPGI IEGAAQGKGR GRQVIAVART ADVIIMMLDA TKGEVQRSLL EKELESVGIR LNKHKPNIYF KPKKGGGISF NSTVMLTQCS EKLVQLILHE YKIFNAEVLF REDCSPDEFI DVIVGNRVYM PCLYVYNKID QISMEEVDRL ARKPNSVVIS CGMKLNLDYL LEMLWEYLAL TCIYTKKRGQ RPDFTDAIIL RKGASVEHVC HRIHRSLASQ FKYALVWGTS TKYSPQRVGL THTMEHEDVI QIVKK (1-364 aa encoded by BC000493)

Target Information

3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

DRG2 Depletion Promotes Endothelial Cell Senescence and Vascular Endothelial Dysfunction.

International journal of molecular sciences

Le AN,Park SS,Le MX,Lee UH,Ko BK,Lim HR,Yu R,Choi SH,Lee BJ,Ham SY,Ha CM,Park JW

Sun Mar 06 00:00:00 UTC 2022

Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Chase R,de la Peña JB,Smith PR,Lawson J,Lou TF,Stanowick AD,Black BJ,Campbell ZT

Fri Jul 01 00:00:00 UTC 2022

DRG2 Accelerates Senescence via Negative Regulation of SIRT1 in Human Diploid Fibroblasts.

Oxidative medicine and cellular longevity

Li BS,Jin AL,Zhou Z,Seo JH,Choi BM

Mon Feb 14 00:00:00 UTC 2022

DRG2 Accelerates Senescence via Negative Regulation of SIRT1 in Human Diploid Fibroblasts.

Oxidative medicine and cellular longevity

Li BS,Jin AL,Zhou Z,Seo JH,Choi BM

Mon Feb 14 00:00:00 UTC 2022

DRG2 Accelerates Senescence via Negative Regulation of SIRT1 in Human Diploid Fibroblasts.

Oxidative medicine and cellular longevity

Li BS,Jin AL,Zhou Z,Seo JH,Choi BM

Mon Feb 14 00:00:00 UTC 2022

Developmentally regulated GTP-binding protein 2 levels in prostate cancer cell lines impact docetaxel-induced apoptosis.

Investigative and clinical urology

Kim SC,Lee WH,Kim SH,Abdulkhayevich AA,Park JW,Kim YM,Moon KH,Lee SH,Park S

Thu Jul 01 00:00:00 UTC 2021

Translatome and Transcriptome Profiling of Hypoxic-Induced Rat Cardiomyocytes.

Molecular therapy. Nucleic acids

Shen Z,Zeng L,Zhang Z

Fri Dec 04 00:00:00 UTC 2020

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.

Nature chemical biology

Markolovic S,Zhuang Q,Wilkins SE,Eaton CD,Abboud MI,Katz MJ,McNeil HE,Leśniak RK,Hall C,Struwe WB,Konietzny R,Davis S,Yang M,Ge W,Benesch JLP,Kessler BM,Ratcliffe PJ,Cockman ME,Fischer R,Wappner P,Chowdhury R,Coleman ML,Schofield CJ

Sun Jul 01 00:00:00 UTC 2018

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.

Nature chemical biology

Sun Jul 01 00:00:00 UTC 2018

DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells.

Molecules and cells

Dang T,Jang SH,Back SH,Park JW,Han IS

Mon Dec 31 00:00:00 UTC 2018

DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells.

Molecules and cells

Dang T,Jang SH,Back SH,Park JW,Han IS

Mon Dec 31 00:00:00 UTC 2018

DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells.

Molecules and cells

Dang T,Jang SH,Back SH,Park JW,Han IS

Mon Dec 31 00:00:00 UTC 2018

DRG2 Deficiency Causes Impaired Microtubule Dynamics in HeLa Cells.

Molecules and cells

Dang T,Jang SH,Back SH,Park JW,Han IS

Mon Dec 31 00:00:00 UTC 2018

Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1.

Biochemical and biophysical research communications

Vo MT,Ko MS,Lee UH,Yoon EH,Lee BJ,Cho WJ,Ha CM,Kim K,Park JW

Sat May 13 00:00:00 UTC 2017

Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1.

Biochemical and biophysical research communications

Vo MT,Ko MS,Lee UH,Yoon EH,Lee BJ,Cho WJ,Ha CM,Kim K,Park JW

Sat May 13 00:00:00 UTC 2017

RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.

Molecular and cellular endocrinology

Grötsch H,Kunert M,Mooslehner KA,Gao Z,Struve D,Hughes IA,Hiort O,Werner R

Fri Jul 06 00:00:00 UTC 2012

RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.

Molecular and cellular endocrinology

Grötsch H,Kunert M,Mooslehner KA,Gao Z,Struve D,Hughes IA,Hiort O,Werner R

Fri Jul 06 00:00:00 UTC 2012

RWDD1 interacts with the ligand binding domain of the androgen receptor and acts as a coactivator of androgen-dependent transactivation.

Molecular and cellular endocrinology

Grötsch H,Kunert M,Mooslehner KA,Gao Z,Struve D,Hughes IA,Hiort O,Werner R

Fri Jul 06 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: developmentally regulated GTP binding protein 2; developmentally regulated GTP-binding protein 2; Developmentally-regulated GTP-binding protein 2; DRG-2; TRAFAC GTPase DRG2; Translation factor GTPase DRG2

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Gene Aliases: AI255295; AI461605; DRG2; RGD1562380

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UniProt ID: (Human) P55039, (Mouse) Q9QXB9

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Entrez Gene ID: (Human) 1819, (Rat) 497915, (Mouse) 13495

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Function(s)

protein binding GTP binding nucleotide binding

Process(es)

biological_process signal transduction

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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DRG2 Polyclonal Antibody

DRG2 Antibody (14743-1-AP) in ICC/IF

Product Details

14743-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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