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Invitrogen
DSCAM Polyclonal Antibody
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FIGURE: 1 / 2
DSCAM Antibody (PA5-47523) in ICC/IF
Immunocytochemistry analysis of DSCAM in immersion fixed A172 human glioblastoma cell line. Samples were incubated in DSCAM polyclonal antibody (Product # PA5-47523) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue).
Product Details
PA5-47523
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human DSCAM long isoform Glu18-Met1595
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610176
Product Specific Information
In direct ELISAs, approximately 10% cross-reactivity with recombinant human DSCAM-L1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs), and is involved in human central and peripheral nervous system development. This gene is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell adhesion molecule DSCAM; CHD2; Down syndrome cell adhesion molecule
Gene Aliases: CHD2; CHD2-42; CHD2-52; DSCAM
UniProt ID: (Human) O60469
Entrez Gene ID: (Human) 1826
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
nervous system development
synapse assembly
locomotory behavior
retina layer formation
positive regulation of phosphorylation
dendrite morphogenesis
positive regulation of axon extension involved in axon guidance
post-embryonic retina morphogenesis in camera-type eye
camera-type eye photoreceptor cell differentiation
dendrite self-avoidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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