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          • Primary Antibodies ›
          • RCAN1 Antibodies

          Abnova

          DSCR1 Polyclonal Antibody, MaxPab™

          View all (23) RCAN1 antibodies
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          Datasheet
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          Cite DSCR1 Polyclonal Antibody, MaxPab™

          • Antibody Testing Data (1)
          DSCR1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          DSCR1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          DSCR1 Antibody (H00001827-B01P) in WB

          Western Blot analysis of RCAN1 expression in transfected 293T cell line by RCAN1 MaxPab polyclonal antibody. Lane 1: DSCR1 transfected lysate(12.87 KDa). Lane 2: Non-transfected lysate. . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          DSCR1 Antibody in Western Blot (WB)

          Product Details

          H00001827-B01P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          10-100 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          DSCR1 (NP_981962.1, 1 a.a. approximately 117 a.a) full-length human protein.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Wet ice

          Product Specific Information

          Product may be used with Western Blot (Transfected lysate).

          The Isotype of this product is composed of an IgG Mixture.

          Immunogen sequence: MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS

          Target Information

          The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Adapt78; Calcipressin-1; calcium and oxidant-inducible mRNA; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical region protein 1; MCIP1; modulatory calcineurin-interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; Regulator of calcineurin 1

          View more View less

          Gene Aliases: ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCAN1; RCN1

          View more View less

          UniProt ID: (Human) P53805

          View more View less

          Entrez Gene ID: (Human) 1827

          View more View less

          Function(s)
          nucleotide binding DNA binding transcription factor activity, sequence-specific DNA binding calcium-dependent protein serine/threonine phosphatase regulator activity
          Process(es)
          regulation of transcription, DNA-templated signal transduction central nervous system development blood circulation calcineurin-NFAT signaling cascade regulation of catalytic activity regulation of calcineurin-NFAT signaling cascade
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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