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Invitrogen
DST Polyclonal Antibody
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Product Details
PA5-76027
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human DST.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719755
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; BPA; Bullous pemphigoid antigen 1; bullous pemphigoid antigen 1, isoform 5; bullous pemphigoid antigen 1, isoforms 1/2/3/4; bullous pemphigoid antigen 1, isoforms 6/7; Dystonia musculorum protein; Dystonin; Hemidesmosomal plaque protein; Microtubule actin cross-linking factor 2; trabeculin-beta
Gene Aliases: 2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; BP240; BPA; Bpag; BPAG1; BPAG1-n; CATX-15; CATX15; D6S1101; DMH; DST; DT; EBSB2; HSAN6; KIAA0728; MACF2; mKIAA0728; nmf203; nmf339
UniProt ID: (Human) Q03001, (Mouse) Q91ZU6
Entrez Gene ID: (Human) 667, (Mouse) 13518, (Rat) 316313
cytoskeleton organization
cell cycle arrest
cell adhesion
axonogenesis
retrograde axonal transport
regulation of microtubule polymerization or depolymerization
cytoplasmic microtubule organization
intracellular transport
integrin-mediated signaling pathway
response to wounding
maintenance of cell polarity
intermediate filament cytoskeleton organization
cell motility
microtubule cytoskeleton organization
hemidesmosome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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