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Bioss
DTNBP1 Polyclonal Antibody
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Product Details
BS-1561R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human DTNBP1, amino acids 101-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Dtnbp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 8; Biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; distrobrevin binding protein 1; DKFZp564K192; DTBP1; Dysbindin; Dysbindin-1; Dystrobrevin-binding protein 1; FLJ30031; Hermansky-Pudlak syndrome 7 protein; Hermansky-Pudlak syndrome 7 protein homolog; HPS7 protein; HPS7 protein homolog; Hps7-like protein; MGC20210; OTTHUMP00000221462; OTTHUMP00000221485; RP1-147M19.1; sandy
Gene Aliases: 5430437B18Rik; AW048963; BLOC1S8; DBND; DTNBP1; dysbindin; HPS7; My031; SDY
UniProt ID: (Human) Q96EV8, (Mouse) Q91WZ8, (Rat) Q5M834
Entrez Gene ID: (Human) 84062, (Mouse) 94245, (Rat) 641528
positive regulation of neurotransmitter secretion
blood coagulation
anterograde axonal transport
positive regulation of gene expression
regulation of dopamine secretion
neuron projection development
actin cytoskeleton reorganization
melanosome organization
regulation of JUN kinase activity
anterograde synaptic vesicle transport
neuron projection morphogenesis
platelet dense granule organization
regulation of dopamine receptor signaling pathway
organelle organization
muscle organ development
response to stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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