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Invitrogen
DTNBP1 Polyclonal Antibody
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DTNBP1 Antibody (PA5-119711) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded mouse testis tissue using DTNBP1 Polyclonal Antibody (Product # PA5-119711). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the DTNBP1 antibody at a dilution ... View More
Product Details
PA5-119711
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within human Dysbindin aa 150-351
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.4, with 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913284
Product Specific Information
Positive Control: Daudi cell lysate, MCF-7 cell lysate, HL-60 cell lysate, human spleen tissue, mouse testis tissue, MCF-7.
Subcellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Membrane, Nucleus, Postsynaptic cell membrane, Synapse
Target Information
Dtnbp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 8; Biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; DKFZp564K192; DTBP1; Dysbindin; Dysbindin-1; Dystrobrevin-binding protein 1; FLJ30031; Hermansky-Pudlak syndrome 7 protein; Hermansky-Pudlak syndrome 7 protein homolog; HPS7 protein; HPS7 protein homolog; Hps7-like protein; MGC20210; OTTHUMP00000221462; OTTHUMP00000221485; RP1-147M19.1; sandy
Gene Aliases: 5430437B18Rik; AW048963; BLOC1S8; DBND; DTNBP1; dysbindin; HPS7; My031; SDY
UniProt ID: (Human) Q96EV8, (Mouse) Q91WZ8
Entrez Gene ID: (Human) 84062, (Mouse) 94245
positive regulation of neurotransmitter secretion
blood coagulation
anterograde axonal transport
positive regulation of gene expression
regulation of dopamine secretion
neuron projection development
actin cytoskeleton reorganization
melanosome organization
regulation of JUN kinase activity
anterograde synaptic vesicle transport
neuron projection morphogenesis
platelet dense granule organization
regulation of dopamine receptor signaling pathway
organelle organization
muscle organ development
response to stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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