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Proteintech
DTX1 Polyclonal Antibody
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Product Details
18350-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DTX1 Fusion Protein Ag13172 (1-374 aa encoded by BC048216)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes DTX1 protein (72 kDa) and it's isoforms (about 60 kDa).
Immunogen sequence: MSRPGHGGL MPVNGLGFPP QNVARVVVWE WLNEHSRWRP YTATVCHHIE NVLKEDARGS VVLGQVDAQL VPYIIDLQSM HQFRQDTGTM RPVRRNFYDP SSAPGKGIVW EWENDGGAWT AYDMDICITI QNAYEKQHPW LDLSSLGFCY LIYFNSMSQM NRQTRRRRRL RRRLDLAYPL TVGSIPKSQS WPVGASSGQP CSCQQCLLVN STRAASNAIL ASQRRKAPPA PPLPPPPPPG GPPGALAVRP SATFTGAALW AAPAAGPAEP APPPGAPPRS PGAPGGARTP GQNNLNRPGP QRTTSVSARA SIPPGVPALP VKNLNGTGPV HPALAGMTGI LLCAAGLPVC LTRAPKPILH PPPVSKSDVK PVPGV (1-374 aa encoded by BC048216)
Target Information
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deltex 1; deltex 1, E3 ubiquitin ligase; deltex homolog 1; Deltex1; E3 ubiquitin-protein ligase DTX1; fractionated x-irradiation induced transcript 1; FXI-T1; hDTX1; mDTX1; Protein deltex-1; RING-type E3 ubiquitin transferase DTX1
Gene Aliases: DTX1; Fxit1; hDx-1; mKIAA4160
UniProt ID: (Human) Q86Y01, (Mouse) Q61010
Entrez Gene ID: (Human) 1840, (Rat) 687424, (Mouse) 14357
transcription coactivator activity
Notch binding
protein binding
zinc ion binding
ligase activity
SH3 domain binding
ubiquitin protein ligase binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Notch signaling pathway
regulation of Notch signaling pathway
glial cell differentiation
negative regulation of T cell differentiation
negative regulation of neuron differentiation
transcription, DNA-templated
transcription from RNA polymerase II promoter
cell surface receptor signaling pathway
protein ubiquitination
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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