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Invitrogen
DUOX2 Polyclonal Antibody
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DUOX2 Antibody (PA5-143875) in IHC (P)
Immunohistochemistry analysis of DUOX2 in paraffin-embedded section of mouse colon tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with DUOX2 Polyclonal antibody (Product # PA5-143875) using a dilution of 2 μg/mL overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as... View More
Product Details
PA5-143875
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived mouse Duox2 recombinant protein (Position: A63-D403).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3075089
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: rat liver tissue, mouse liver tissue. IHC: mouse colon tissue. Flow: HEPA1-6 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dual oxidase 2; Large NOX 2; Long NOX 2; NADH/NADPH thyroid oxidase THOX2; Thyroid oxidase 2
Gene Aliases: A430065P05Rik; Duox2; LNOX2; NOXEF2; P138-TOX; THOX2
UniProt ID: (Rat) Q9ES45
Entrez Gene ID: (Mouse) 214593, (Rat) 79107
fertilization
response to virus
cytokine-mediated signaling pathway
bone mineralization
thyroid gland development
multicellular organism growth
thyroid hormone metabolic process
hormone metabolic process
inner ear development
adenohypophysis morphogenesis
response to cAMP
oxidation-reduction process
thyroid hormone generation
response to oxidative stress
cuticle development
hormone biosynthetic process
hydrogen peroxide catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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