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Invitrogen
DUSP10 Polyclonal Antibody
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FIGURE: 1 / 1
DUSP10 Antibody (PA5-109665) in WB
Western blot analysis of DUSP10 in extracts of BT-474 cells. Samples were incubated with DUSP10 Polyclonal antibody (Product # PA5-109665) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-109665
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DUSP10 (NP_009138.1).
Conjugate
Form
Liquid
Concentration
0.75 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855076
Product Specific Information
Immunogen sequence: MPPSPLDDRV VVALSRPVRP QDLNLCLDSS YLGSANPGSN SHPPVIATTV VSLKAANLTY MPSSSGSARS LNCGCSSASC CTVATYDKDN QAQTQAIAAG TTTTAIGTST TCPANQMVNN NENTGSLSPS SGVGSPVSGT PKQLASIKII YPNDLAKKMT KCSKSHLPSQ GPVIIDCRPF MEYNKSHIQG AVHINCADKI SRRRLQQGKI TVLDLISCRE GKDSFKRIFS KEIIVYDENT NEPSRVMPSQ PLHIVLESLK REGKEPLVLK GGLSSFKQNH ENLCDNSLQL QECREVGGGA
Target Information
Microsomal long and very long chain fatty acid elongation uses malonyl-CoA as the 2-carbon donor and consists of 4 sequential reactions. GPSN2 catalyzes the final step, reducing trans-2, 3-enoyl-CoA to saturated acyl-CoA. Microsomal long and very long chain fatty acid elongation uses malonyl-CoA as the 2-carbon donor and consists of 4 sequential reactions. TER catalyzes the final step, reducing trans-2, 3-enoyl-CoA to saturated acyl-CoA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dual specificity phosphatase MKP-5; Dual specificity protein phosphatase 10; MAP kinase phosphatase 5; Mitogen-activated protein kinase phosphatase 5; serine/threonine specific protein phosphatase
Gene Aliases: 2610306G15Rik; AI158871; DUSP10; MKP-5; MKP5
UniProt ID: (Human) Q9Y6W6, (Mouse) Q9ESS0
Entrez Gene ID: (Human) 11221, (Mouse) 63953, (Rat) 63995
inactivation of MAPK activity
regulation of adaptive immune response
protein dephosphorylation
dephosphorylation
response to lipopolysaccharide
negative regulation of stress-activated MAPK cascade
negative regulation of JUN kinase activity
negative regulation of protein kinase activity by regulation of protein phosphorylation
regulation of innate immune response
negative regulation of JNK cascade
oligodendrocyte differentiation
negative regulation of oligodendrocyte differentiation
negative regulation of respiratory burst involved in inflammatory response
regulation of brown fat cell differentiation
response to stress
JNK cascade
peptidyl-tyrosine dephosphorylation
response to organic substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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