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Invitrogen
DUSP5 Monoclonal Antibody (OTI5H9)
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Product Details
MA5-27383
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI5H9
Immunogen
Human recombinant protein fragment corresponding to amino acids 125-384 of DUSP5 produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2723104
Target Information
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: candidate plasticity-related gene 21; Dual specificity protein phosphatase 5; Dual specificity protein phosphatase hVH3; MAP-kinase phosphatase (cpg21); MAP-kinase phosphatase CPG21; serine/threonine specific protein phosphatase; VH1-like phosphatase 3
Gene Aliases: Cpg21; DUSP; DUSP5; HVH3; VH3
UniProt ID: (Human) Q16690, (Rat) O54838
Entrez Gene ID: (Human) 1847, (Rat) 171109
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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