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DVL3 Polyclonal Antibody

DVL3 Antibody in Immunocytochemistry (ICC/IF)

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DVL3 Antibody (13444-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using 13444-1-AP (DVL3 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

DVL3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

DVL3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

13444-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:6,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000

Immunocytochemistry (ICC/IF)

1:20-1:200

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DVL3 Fusion Protein Ag4272 (1-319 aa encoded by BC032459)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.31 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGETKIIYH LDGQETPYLV KLPLPAERVT LADFKGVLQR PSYKFFFKSM DDDFGVVKEE ISDDNAKLPC FNGRVVSWLV SAEGSHPDPA PFCADNPSEL PPPMERTGGI GDSRPPSFHP HAGGGSQENL DNDTETDSLV SAQRERPRRR DGPEHATRLN GTAKGERRRE PGGYDSSSTL MSSELETTSF FDSDEDDSTS RFSSSTEQSS ASRLMRRHKR RRRKQKVSRI ERSSSFSSIT DSTMSLNIIT VTLNMEKYNF LGISIVGQSN ERGDGGIYIG SIMKGGAVAA DGRIEPGDML LQVNEINFEN MSNDDAVRVL (1-319 aa encoded by BC032459)

Target Information

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila disheveled gene, dsh. The Drosophila disheveled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3.

Biological procedures online

Zhu M,Zhang J,Bian S,Zhang X,Shen Y,Ni Z,Xu S,Cheng C,Zheng W

Fri Dec 02 00:00:00 UTC 2022

Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3.

Biological procedures online

Zhu M,Zhang J,Bian S,Zhang X,Shen Y,Ni Z,Xu S,Cheng C,Zheng W

Fri Dec 02 00:00:00 UTC 2022

Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3.

Biological procedures online

Zhu M,Zhang J,Bian S,Zhang X,Shen Y,Ni Z,Xu S,Cheng C,Zheng W

Fri Dec 02 00:00:00 UTC 2022

Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling.

The Journal of cell biology

Landin Malt A,Hogan AK,Smith CD,Madani MS,Lu X

Mon Oct 05 00:00:00 UTC 2020

The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer.

Oncogene

Li K,Zhang J,Tian Y,He Y,Xu X,Pan W,Gao Y,Chen F,Wei L

Sun Mar 01 00:00:00 UTC 2020

Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled.

The Journal of cell biology

Lee M,Hwang YS,Yoon J,Sun J,Harned A,Nagashima K,Daar IO

Mon Aug 05 00:00:00 UTC 2019

Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled.

The Journal of cell biology

Lee M,Hwang YS,Yoon J,Sun J,Harned A,Nagashima K,Daar IO

Mon Aug 05 00:00:00 UTC 2019

Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cells.

Oncotarget

Zhu X,Wu X,Cheng J,Liao H,Di X,Li L,Li R,Zhou Y,Zhang X

Tue Jul 18 00:00:00 UTC 2017

SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network.

Cancer letters

Li X,Xu Y,Chen Y,Chen S,Jia X,Sun T,Liu Y,Li X,Xiang R,Li N

Mon Aug 19 00:00:00 UTC 2013

SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network.

Cancer letters

Li X,Xu Y,Chen Y,Chen S,Jia X,Sun T,Liu Y,Li X,Xiang R,Li N

Mon Aug 19 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: dishevelled 3 (homologous to Drosophila dsh); dishevelled, dsh homolog 3; Dishevelled-3; DSH homolog 3; dvl-3; OTTHUMP00000210778; Segment polarity protein dishevelled homolog DVL-3

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Gene Aliases: DRS3; DVL3; KIAA0208

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UniProt ID: (Human) Q92997

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Entrez Gene ID: (Human) 1857

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Function(s)

protease binding receptor binding frizzled binding protein binding beta-catenin binding protein binding, bridging protein heterodimerization activity Rac GTPase binding

Process(es)

positive regulation of protein phosphorylation outflow tract septum morphogenesis Wnt signaling pathway intracellular signal transduction non-canonical Wnt signaling pathway non-canonical Wnt signaling pathway via JNK cascade response to drug positive regulation of JUN kinase activity positive regulation of GTPase activity positive regulation of transcription, DNA-templated protein stabilization canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway negative regulation of canonical Wnt signaling pathway cochlea morphogenesis planar cell polarity pathway involved in neural tube closure regulation of cellular protein localization beta-catenin destruction complex disassembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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DVL3 Polyclonal Antibody

DVL3 Antibody (13444-1-AP) in ICC/IF

Product Details

13444-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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