Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
DYNLL1 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-65251
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human DYNLL1. Recombinant protein control fragment (Product #RP-104710).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2663062
Product Specific Information
Immunogen sequence: MCDRKAVIKNA DMSEEMQQDS VECATQALEK YNIEKDIAAH IKKEFDKKYN PTWHCIV
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
Target Information
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1, 200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 8 kDa dynein light chain; cytoplasmic dynein light polypeptide; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1MGC126138; Dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; H LC8; LC8-type 1; MGC126137; MGC126138; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase
Gene Aliases: DLC1; DLC8; DNCL1; DNCLC1; DYNLL1; HDLC1; LC8; LC8a; PIN
UniProt ID: (Human) P63167
Entrez Gene ID: (Human) 8655
G2/M transition of mitotic cell cycle
transcription, DNA-templated
regulation of transcription, DNA-templated
ER to Golgi vesicle-mediated transport
apoptotic process
female gamete generation
anatomical structure morphogenesis
viral process
macroautophagy
antigen processing and presentation of exogenous peptide antigen via MHC class II
substantia nigra development
actin cytoskeleton organization
intraciliary retrograde transport
negative regulation of phosphorylation
cilium morphogenesis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support