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Invitrogen
DYNLRB1 Polyclonal Antibody
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DYNLRB1 Antibody (PA5-103808) in IHC (P)
Immunohistochemistry analysis of DYNLRB1 in mouse spleen tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with DYNLRB1 polyclonal antibody (Product # PA5-103808) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103808
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DYNLRB1(Accession Q9NP97), corresponding to amino acid residues I50-E96.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2853141
Product Specific Information
Antibody detects endogenous levels of total DYNLRB1.
Target Information
The DYNLRB1 gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bithoraxoid-like protein; BLP; Dynein light chain 2A, cytoplasmic; Dynein light chain roadblock-type 1; dynein, cytoplasmic, light chain 2A; dynein, cytoplasmic, light polypeptide 2A; dynein, light chain, roadblock-type 1; Dynein-associated protein Km23; dynein-associated protein RKM23; Roadblock domain-containing protein 1; ROBL/LC7-like 1; robl/LC7-like protein
Gene Aliases: 2010012N15Rik; 2010320M17Rik; 9430076K19Rik; AV124457; BITH; BLP; DNCL2A; DNLC2A; DYNLRB1; HSPC162; km23; km23-1; ROBLD1
UniProt ID: (Human) Q9NP97, (Rat) P62628, (Mouse) P62627
Entrez Gene ID: (Human) 83658, (Rat) 170714, (Mouse) 67068
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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