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          • Primary Antibodies ›
          • DRD1 Antibodies

          Fabgennix

          Dopamine Receptor D1 Polyclonal Antibody, Biotin

          View all (30) DRD1 antibodies

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          Datasheet
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          Datasheet
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          Cite Dopamine Receptor D1 Polyclonal Antibody, Biotin

          Product Details

          D1R-M-BIOTIN

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (IHC)

          1:50-1:250
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:250
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -

          Immunomicroscopy (IM)

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 250-300 on mouse D(1A) dopamine receptor.
          View immunogen

          Conjugate

          Biotin Biotin Biotin

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: D(1A) dopamine receptor; D1 receptor; D1A dopamine receptor; D1a receptor; Dopamine 1 receptor; Dopamine D1 receptor; dopamine receptor D1A; Dopamine-1A receptor; G protein-coupled receptor DRD1

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          Gene Aliases: C030036C15Rik; D1a; Drd-1; Drd1; Drd1a; Gpcr15

          View more View less

          UniProt ID: (Mouse) Q61616

          View more View less

          Entrez Gene ID: (Mouse) 13488, (Rat) 24316

          View more View less

          Function(s)
          dopamine neurotransmitter receptor activity, coupled via Gs G-protein alpha-subunit binding signal transducer activity G-protein coupled receptor activity dopamine neurotransmitter receptor activity receptor binding protein binding drug binding G-protein coupled amine receptor activity protein phosphatase binding angiotensin receptor binding D3 dopamine receptor binding protein complex binding dopamine binding protein heterodimerization activity ATPase binding
          Process(es)
          temperature homeostasis conditioned taste aversion behavioral fear response synaptic transmission, dopaminergic startle response response to amphetamine negative regulation of protein kinase activity protein import into nucleus intracellular protein transport muscle contraction signal transduction G-protein coupled receptor signaling pathway G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-activating dopamine receptor signaling pathway dopamine receptor signaling pathway chemical synaptic transmission sensory perception of chemical stimulus learning memory mating behavior grooming behavior locomotory behavior adult walking behavior feeding behavior associative learning visual learning positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway astrocyte development dopamine transport transmission of nerve impulse neuronal action potential regulation of vasoconstriction calcium-mediated signaling dentate gyrus development striatum development hippocampus development cerebral cortex GABAergic interneuron migration positive regulation of cell migration negative regulation of cell migration peristalsis positive regulation of cAMP biosynthetic process phosphatidylinositol catabolic process operant conditioning social behavior regulation of dopamine metabolic process response to cocaine vasodilation negative regulation of circadian sleep/wake cycle, sleep response to drug maternal behavior regulation of ion transport positive regulation of adenylate cyclase activity positive regulation of membrane potential glucose import phosphatidylinositol metabolic process habituation sensitization behavioral response to cocaine regulation of long-term neuronal synaptic plasticity positive regulation of release of sequestered calcium ion into cytosol positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway positive regulation of synaptic transmission, glutamatergic prepulse inhibition phospholipase C-activating dopamine receptor signaling pathway long-term synaptic potentiation long term synaptic depression cellular response to catecholamine stimulus positive regulation of long-term synaptic potentiation positive regulation of feeding behavior synapse assembly response to organonitrogen compound response to organic cyclic compound response to activity orbitofrontal cortex development response to food response to estradiol response to retinoic acid cellular response to insulin stimulus response to nicotine response to antidepressant response to amino acid response to morphine response to ethanol response to steroid hormone cellular response to hypoxia
          It has to be done as per old AB suggested Products section.
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