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Invitrogen
Dopamine Transporter Polyclonal Antibody
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Dopamine Transporter Antibody (PA5-78382) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Dopamine Transporter was performed in DIV9 rat E18 primary cortical neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Dopamine Transporter Polyclonal Antibody (Product # PA5 78382) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-78382
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Zebrafish
Published species
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of Mouse Dopamine Transporter. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.94 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735739
Product Specific Information
Positive Control: rat olfactory bulb, mouse olfactory bulb
Predicted Reactivity: Human (93%), Dog (86%), Rhesus Monkey (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DA transporter; DAT; dopamine transporter; dopamine transporter 1; Sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter), member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Solute carrier family 6 member 3; solute carrier family 6, member 3
Gene Aliases: DAT; DAT1; PKDYS; SLC6A3
UniProt ID: (Human) Q01959, (Rat) P23977, (Mouse) Q61327
Entrez Gene ID: (Human) 6531, (Rat) 24898, (Mouse) 13162, (Zebrafish) 80787
protease binding
receptor binding
dopamine transmembrane transporter activity
dopamine:sodium symporter activity
protein binding
drug binding
monoamine transmembrane transporter activity
protein complex binding
dopamine binding
metal ion binding
protein N-terminus binding
protein phosphatase 2A binding
neurotransmitter:sodium symporter activity
symporter activity
neurotransmitter transport
aging
lactation
sensory perception of smell
locomotory behavior
response to iron ion
response to organic cyclic compound
monoamine transport
dopamine transport
adenohypophysis development
response to nicotine
positive regulation of multicellular organism growth
regulation of dopamine metabolic process
response to cocaine
dopamine biosynthetic process
dopamine catabolic process
response to drug
response to ethanol
response to cAMP
prepulse inhibition
ammonium transmembrane transport
cation transmembrane transport
transport
organic cation transport
sodium ion transmembrane transport
neurotransmitter biosynthetic process
dopamine uptake involved in synaptic transmission
dopamine uptake
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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