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Invitrogen
Dynamin 3 Polyclonal Antibody
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FIGURE: 1 / 5
Dynamin 3 Antibody (PA1-662) in ICC/IF
Immunofluorescence analysis of Dynamin III was performed using 70% confluent log phase SH-SY5Y cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Dynamin III Rabbit Polyclonal Antibody (Product # PA1-662) at 2 µg/mL in 0.1% BSA and incubated for 3 hours ... View More
Product Details
PA1-662
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic Peptide: C P(623) D K S F T E N D E N G Q A E N F(639)
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Purification
Ammonium sulfate precipitation
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2093694
Product Specific Information
PA1-662 detects dynamin III (Dyn3) from rat, mouse, and human tissues and cells.
PA1-662 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~100 kDa protein representing Dyn3 from HeLa cell lysate.
PA1-662 immunizing peptide corresponds to amino acid residues 623-639 from rat Dyn3. PA1-662 immunizing peptide (Cat. # PEP-057) is available for use in neutralization and control experiments.
Target Information
The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dyna III; dynamin family member; Dynamin III; Dynamin, testicular; Dynamin-3; T-dynamin; testicular dynamin
Gene Aliases: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; DNM3; Dyn3; Dyna III; dynamin-2; KIAA0820; mKIAA0820
UniProt ID: (Human) Q9UQ16, (Mouse) Q8BZ98, (Rat) Q08877
Entrez Gene ID: (Human) 26052, (Mouse) 103967, (Rat) 171574
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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