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          • Primary Antibodies ›
          • Dynamin 3 Antibodies

          Invitrogen

          Dynamin 3 Polyclonal Antibody

          View all (9) Dynamin 3 antibodies

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          Cite Dynamin 3 Polyclonal Antibody

          • Antibody Testing Data (3)
          Dynamin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Dynamin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 3

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          Dynamin 3 Antibody (PA5-141094) in IHC (P)

          Immunohistochemistry analysis of Dynamin 3 in paraffin-embedded mouse brain tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with Dynamin 3 Polyclonal antibody (Product # PA5-141094) using a dilution of 1:200 for 30 minu... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Dynamin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Dynamin 3 Antibody in Western Blot (WB)
          Dynamin 3 Antibody in Western Blot (WB)

          Product Details

          PA5-141094

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide within human Dynamin 3 aa 820-869.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          TBS, pH 7.4, with 50% glycerol, 0.2% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Wet ice

          RRID

          AB_2932546

          Target Information

          The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Dyna III; dynamin family member; Dynamin III; Dynamin, testicular; Dynamin-3; T-dynamin; testicular dynamin

          View more View less

          Gene Aliases: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; DNM3; Dyn3; Dyna III; dynamin-2; KIAA0820; mKIAA0820

          View more View less

          UniProt ID: (Human) Q9UQ16, (Mouse) Q8BZ98, (Rat) Q08877

          View more View less

          Entrez Gene ID: (Human) 26052, (Mouse) 103967, (Rat) 171574

          View more View less

          Function(s)
          GTPase activity protein binding GTP binding type 1 metabotropic glutamate receptor binding type 5 metabotropic glutamate receptor binding nitric-oxide synthase binding nucleotide binding hydrolase activity
          Process(es)
          endocytosis synapse assembly metabolic process filopodium assembly positive regulation of filopodium assembly regulation of dendritic spine morphogenesis negative regulation of dendritic spine morphogenesis sperm ejaculation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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