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Invitrogen
Dynamin 3 Polyclonal Antibody
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Product Details
PA5-90253
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 410-555 of human Dynamin 3 (NP_0012651811)
Conjugate
Form
Liquid
Concentration
2.34 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805984
Product Specific Information
Immunogen sequence: EAIVKKQIVK LKGPSLKSVD LVIQELINTV KKCTKKLANF PRLCEETERI VANHIREREG KTKDQVLLLI DIQVSYINTN HEDFIGFANA QQRSSQVHKK TTVGNQVIRK GWLTISNIGI MKGGSKGYWF VLTAESLSWY KDDENI; Positive Samples: mouse brain, rat brain; Cellular Location: Cytoplasm, cytoskeleton
Target Information
The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dyna III; Dynamin III; Dynamin, testicular; Dynamin-3; T-dynamin; testicular dynamin
Gene Aliases: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; Dnm3; Dyn3; dynamin-2; Kiaa0820; mKIAA0820
UniProt ID: (Mouse) Q8BZ98, (Rat) Q08877
Entrez Gene ID: (Mouse) 103967, (Rat) 171574
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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