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Invitrogen
Dynamin 3 Recombinant Rabbit Monoclonal Antibody (5X7T4)
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FIGURE: 1 / 1
Dynamin 3 Antibody (MA5-37890) in WB
Western blot analysis of Dynamin 3 in extracts of various cell lines. Samples were incubated with Dynamin 3 Monoclonal antibody (Product # MA5-37890) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
MA5-37890
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5X7T4
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human Dynamin 3 (Q9UQ16)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897810
Product Specific Information
Positive Samples: SH-SY5Y, Mouse testis, Mouse spinal cord, Mouse brain
Immunogen sequence: ELLAQLYSSE DQNTLMEESA EQAQRRDEML RMYQALKEAL GIIGDISTAT VSTPAPPPVD DSWIQHSRRS PPPSPTTQRR PTLSAPLARP TSGRGPAPAI P
Target Information
The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dyna III; dynamin family member; Dynamin III; Dynamin, testicular; Dynamin-3; T-dynamin; testicular dynamin
Gene Aliases: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; DNM3; Dyna III; KIAA0820; mKIAA0820
UniProt ID: (Human) Q9UQ16, (Mouse) Q8BZ98
Entrez Gene ID: (Human) 26052, (Mouse) 103967
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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