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Invitrogen
Dysferlin Recombinant Rabbit Monoclonal Antibody (JF05-54)
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FIGURE: 1 / 6
Dysferlin Antibody (MA5-32524) in ICC/IF
Immunocytochemical analysis of Dysferlin in SW480 cells using a Dysferlin Monoclonal antibody (Product # MA5-32524) as seen in red. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32524
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JF05-54
Immunogen
Synthetic peptide within Human Dysferlin aa 113-162
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809801
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Dysferlin is the protein product of the 2p13 gene that is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM). Dysferlin is normally localized to the muscle plasma membrane. In patients with LGMD2B and MM, immunoreactivity to dysferlin is severely reduced or lost, depending on the type of mutation. This antibody is used for the characterization of LGMD2B and MM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dysferlin; dysferlin variant a; dysferlin_a; dystrophy-associated fer-1-like 1; Dystrophy-associated fer-1-like protein; fer-1-like family member 1; Fer-1-like protein 1; FLJ00175; FLJ90168; limb girdle muscular dystrophy 2B (autosomal recessive)
Gene Aliases: 2310004N10Rik; AI604795; D6Pas3; DYSF; FER1L1; LGMD2B; MMD1
UniProt ID: (Human) O75923, (Mouse) Q9ESD7
Entrez Gene ID: (Human) 8291, (Mouse) 26903
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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