Proteintech

E-cadherin Monoclonal Antibody (6B11F11)

E-cadherin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 13

E-cadherin Antibody (60335-1-IG) in IHC (P)

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 60335-1-IG ( E-cadherin antibody) at dilution of 1:2000 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

E-cadherin Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

E-cadherin Antibody in Western Blot (WB)

E-cadherin Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

60335-1-IG

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:16,000

View 118 publications 118 publications

Immunohistochemistry (IHC)

View 12 publications 12 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:4,000

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 22 publications 22 publications

Flow Cytometry (Flow)

Assay-dependent

View 1 publication 1 publication

Not applicable (N/A)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Pig, Rat

Published species

Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

6B11F11

Immunogen

E-cadherin Fusion Protein Ag15085 (373-622 aa encoded by BC141838)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: PIFNPTTYK GQVPENEANV VITTLKVTDA DAPNTPAWEA VYTILNDDGG QFVVTTNPVN NDGILKTAKG LDFEAKQQYI LHVAVTNVVP FEVSLTTSTA TVTVDVLDVN EAPIFVPPEK RVEVSEDFGV GQEITSYTAQ EPDTFMEQKI TYRIWRDTAN WLEINPDTGA ISTRAELDRE DFEHVKNSTY TALIIATDNG SPVATGTGTL LLILSDVNDN APIPEPRTIF FCERNPKPQV INIIDADLPP I (373-622 aa encoded by BC141838)

Target Information

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Ginsenoside CK Inhibits TGF-β-Induced Epithelial-Mesenchymal Transition in A549 Cell via SIRT1.

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Molecular therapy. Nucleic acids

Lin J,Zeng C,Zhang J,Song Z,Qi N,Liu X,Zhang Z,Li A,Chen F

Fri Sep 03 00:00:00 UTC 2021

YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.

Molecular carcinogenesis

Li Y,Zhu X,Yang M,Wang Y,Li J,Fang J,Guo W,Ma S,Guan F

Thu Jul 01 00:00:00 UTC 2021

Reduced expression of miR-30c-5p promotes hepatocellular carcinoma progression by targeting RAB32.

Molecular therapy. Nucleic acids

He Z,Tian M,Fu X

Fri Dec 03 00:00:00 UTC 2021

MyD88 in myofibroblasts enhances colitis-associated tumorigenesis via promoting macrophage M2 polarization.

Cell reports

Yuan Q,Gu J,Zhang J,Liu S,Wang Q,Tian T,Chen Z,Zhang J

Tue Feb 02 00:00:00 UTC 2021

Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer.

Medical oncology (Northwood, London, England)

Zheng W,Hu J,Lv Y,Bai B,Shan L,Chen K,Dai S,Zhu H

Mon Feb 08 00:00:00 UTC 2021

Expression of Talin-1 in endometriosis and its possible role in pathogenesis.

Reproductive biology and endocrinology : RB&E

Tang X,Li Q,Li L,Jiang J

Tue Mar 09 00:00:00 UTC 2021

EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma.

Pathology, research and practice

Bao S,Ji Z,Shi M,Liu X

Wed Dec 01 00:00:00 UTC 2021

EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma.

Pathology, research and practice

Bao S,Ji Z,Shi M,Liu X

Wed Dec 01 00:00:00 UTC 2021

EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma.

Pathology, research and practice

Bao S,Ji Z,Shi M,Liu X

Wed Dec 01 00:00:00 UTC 2021

EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma.

Pathology, research and practice

Bao S,Ji Z,Shi M,Liu X

Wed Dec 01 00:00:00 UTC 2021

Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis.

Journal of experimental & clinical cancer research : CR

Huang D,Zhang K,Zheng W,Zhang R,Chen J,Du N,Xia Y,Long Y,Gu Y,Xu J,Deng M

Thu Oct 28 00:00:00 UTC 2021

miR-199b-5p-DDR1-ERK signalling axis suppresses prostate cancer metastasis via inhibiting epithelial-mesenchymal transition.

British journal of cancer

Zhao Z,Zhao S,Luo L,Xiang Q,Zhu Z,Wang J,Liu Y,Luo J

Mon Mar 01 00:00:00 UTC 2021

Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.

Journal of Cancer

Wang L,Huang Y,Liu C,Guo M,Ma Z,He J,Wang A,Sun X,Liu Z

Mon Jan 11 00:00:00 UTC 2021

Exosome-Induced Vaginal Tissue Regeneration in a Porcine Mesh Exposure Model.

Female pelvic medicine & reconstructive surgery

Kisby CK,Shadrin IY,Rolland TJ,Stalboerger PG,Zhou B,Trabuco EC,Behfar A,Occhino JA

Fri Oct 01 00:00:00 UTC 2021

An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer Angiogenesis.

Frontiers in oncology

Jin H,Zheng W,Hou J,Peng H,Zhuo H

Tue Jun 22 00:00:00 UTC 2021

Biomimetic Human Disease Model of SARS-CoV-2-Induced Lung Injury and Immune Responses on Organ Chip System.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang M,Wang P,Luo R,Wang Y,Li Z,Guo Y,Yao Y,Li M,Tao T,Chen W,Han J,Liu H,Cui K,Zhang X,Zheng Y,Qin J

Mon Feb 01 00:00:00 UTC 2021

MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.

Bioengineered

Xu W,Ye L,Wu H

Wed Dec 01 00:00:00 UTC 2021

BOP1 Used as a Novel Prognostic Marker and Correlated with Tumor Microenvironment in Pan-Cancer.

Journal of oncology

Li W,Song P,Zhao M,Gao L,Xie J,You C

Tue Oct 05 00:00:00 UTC 2021

Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.

Journal of Cancer

Zou N,Zhang X,Li S,Li Y,Zhao Y,Yang X,Zhu S

Fri Jul 09 00:00:00 UTC 2021

SCARA5 inhibits gastric cancer progression via epithelial-mesenchymal transition suppression.

Journal of Cancer

Zhang H,Liu C,Wang X,Wang Y,Zheng J

Thu Mar 25 00:00:00 UTC 2021

Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.

Cancer management and research

Wu Y,Liu L,Shen X,Liu W,Ma R

Wed Apr 20 00:00:00 UTC 2022

Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.

Cancer management and research

Wu Y,Liu L,Shen X,Liu W,Ma R

Wed Apr 20 00:00:00 UTC 2022

Comparative analysis identifies significant peptides related to asthma mechanism.

American journal of translational research

Zhu D,Wang C,Meng C,Liu Y,Zeng Z,Zhao R,Dong X,Wang X

Tue Jan 18 00:00:00 UTC 2022

miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1.

The Kaohsiung journal of medical sciences

Shen D,Zhao HY,Gu AD,Wu YW,Weng YH,Li SJ,Song JY,Gu XF,Qiu J,Zhao W

Wed Sep 01 00:00:00 UTC 2021

LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.

Annals of translational medicine

Guan Y,Li Y,Yang QB,Yu J,Qiao H

Thu Apr 01 00:00:00 UTC 2021

TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.

Frontiers in cell and developmental biology

Xie C,Zhu J,Yang X,Huang C,Zhou L,Meng Z,Li X,Zhong C

Sun Mar 31 00:00:00 UTC 2024

Tuftelin 1 (TUFT1) Promotes the Proliferation and Migration of Renal Cell Carcinoma via PI3K/AKT Signaling Pathway.

Pathology oncology research : POR

Lin H,Zeng W,Lei Y,Chen D,Nie Z

Mon Jan 03 00:00:00 UTC 2022

Parthenolide inhibits the tumor characteristics of renal cell carcinoma.

International journal of oncology

Liu D,Han Y,Liu L,Ren X,Zhang H,Fan S,Qin T,Li L

Fri Jan 01 00:00:00 UTC 2021

Parthenolide inhibits the tumor characteristics of renal cell carcinoma.

International journal of oncology

Liu D,Han Y,Liu L,Ren X,Zhang H,Fan S,Qin T,Li L

Fri Jan 01 00:00:00 UTC 2021

Knockdown hsa_circ_0063526 inhibits endometriosis progression via regulating the miR-141-5p / EMT axis and downregulating estrogen receptors.

Aging

Wei Z,Hu Y,He X,Zhang M,Zhang X,Wang Y,Fang X,Li L

Thu Dec 30 00:00:00 UTC 2021

EMT changes actin cortex rheology in a cell-cycle-dependent manner.

Biophysical journal

Hosseini K,Frenzel A,Fischer-Friedrich E

Tue Aug 17 00:00:00 UTC 2021

EMT changes actin cortex rheology in a cell-cycle-dependent manner.

Biophysical journal

Hosseini K,Frenzel A,Fischer-Friedrich E

Tue Aug 17 00:00:00 UTC 2021

Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.

Biomaterials

Pan S,Zhang Y,Huang M,Deng Z,Zhang A,Pei L,Wang L,Zhao W,Ma L,Zhang Q,Cui D

Sun Aug 01 00:00:00 UTC 2021

F-Box protein 4 inhibits progression of papillary thyroid cancer.

Steroids

Xu M,Wang Y,Chen M,Hu H,Xia T,Deng D

Mon Feb 01 00:00:00 UTC 2021

Circular RNA circZFPM2 promotes epithelial-mesenchymal transition in endometriosis by regulating miR-205-5p/ZEB1 signalling pathway.

Cellular signalling

Wang D,Cui L,Yang Q,Wang J

Mon Nov 01 00:00:00 UTC 2021

NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.

Frontiers in cell and developmental biology

Dang NN,Li XB,Zhang M,Han C,Fan XY,Huang SH

Tue Sep 07 00:00:00 UTC 2021

Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.

Journal of physiology and biochemistry

Li Y,Zhao Y,Li Y,Zhang X,Li C,Long N,Chen X,Bao L,Zhou J,Xie Y

Mon Feb 01 00:00:00 UTC 2021

Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.

Journal of ethnopharmacology

Wang Y,Chu F,Lin J,Li Y,Johnson N,Zhang J,Gai C,Su Z,Cheng H,Wang L,Ding X

Thu Oct 28 00:00:00 UTC 2021

α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.

Bioengineered

Zhang S,Wang J,Chen T,Wang J,Wang Y,Yu Z,Zhao K,Zheng K,Chen Y,Wang Z,Li B,Wang C,Huang W,Fu Z,Chen J

Wed Dec 01 00:00:00 UTC 2021

α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway.

Bioengineered

Zhang S,Wang J,Chen T,Wang J,Wang Y,Yu Z,Zhao K,Zheng K,Chen Y,Wang Z,Li B,Wang C,Huang W,Fu Z,Chen J

Wed Dec 01 00:00:00 UTC 2021

EIF3H interacts with PDCD4 enhancing lung adenocarcinoma cell metastasis.

American journal of cancer research

Hu Y,Wei X,Lv Y,Xie X,Yang L,He J,Tao X,Ma Y,Su Y,Wu L,Fang W,Liu Z

Thu Mar 28 00:00:00 UTC 2024

GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.

International journal of oncology

Cheng L,Gou L,Wei T,Zhang J

Tue Sep 01 00:00:00 UTC 2020

GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.

International journal of oncology

Cheng L,Gou L,Wei T,Zhang J

Tue Sep 01 00:00:00 UTC 2020

LacdiNAcylation of N-glycans in MDA-MB-231 human breast cancer cells results in changes in morphological appearance and adhesive properties of the cells.

Histochemistry and cell biology

Hirano K,Takada Y,Furukawa K

Wed Jan 01 00:00:00 UTC 2020

LacdiNAcylation of N-glycans in MDA-MB-231 human breast cancer cells results in changes in morphological appearance and adhesive properties of the cells.

Histochemistry and cell biology

Hirano K,Takada Y,Furukawa K

Wed Jan 01 00:00:00 UTC 2020

AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.

Cancer management and research

Xu F,Xu Y,Xiong JH,Zhang JH,Wu J,Luo J,Xiong JP

Wed Apr 13 00:00:00 UTC 2022

miR-145-5p suppresses proliferation, metastasis and EMT of colorectal cancer by targeting CDCA3.

Pathology, research and practice

Chen Q,Zhou L,Ye X,Tao M,Wu J

Wed Apr 01 00:00:00 UTC 2020

A cross-talk between epithelium and endothelium mediates human alveolar-capillary injury during SARS-CoV-2 infection.

Cell death & disease

Wang P,Luo R,Zhang M,Wang Y,Song T,Tao T,Li Z,Jin L,Zheng H,Chen W,Zhao M,Zheng Y,Qin J

Tue Dec 08 00:00:00 UTC 2020

Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.

Cell death & disease

Li X,Ma N,Zhang Y,Wei H,Zhang H,Pang X,Li X,Wu D,Wang D,Yang Z,Zhang S

Tue May 26 00:00:00 UTC 2020

The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.

Oncology research

Wei W,Ma XD,Jiang GM,Shi B,Zhong W,Sun CL,Zhao L,Hou YJ,Wang H

Tue Sep 01 00:00:00 UTC 2020

The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.

Oncology research

Wei W,Ma XD,Jiang GM,Shi B,Zhong W,Sun CL,Zhao L,Hou YJ,Wang H

Tue Sep 01 00:00:00 UTC 2020

Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.

Frontiers in oncology

Guo W,Zhang Z,Li G,Lai X,Gu R,Xu W,Chen H,Xing Z,Chen L,Qian J,Xu S,Zeng F,Deng F

Tue Feb 27 00:00:00 UTC 2024

Oxymatrine reverses 5-fluorouracil resistance by inhibition of colon cancer cell epithelial-mesenchymal transition and NF-κB signaling in vitro.

Oncology letters

Liang L,Wu J,Luo J,Wang L,Chen ZX,Han CL,Gan TQ,Huang JA,Cai ZW

Wed Jan 01 00:00:00 UTC 2020

3D printed in vitro tumor tissue model of colorectal cancer.

Theranostics

Chen H,Cheng Y,Wang X,Wang J,Shi X,Li X,Tan W,Tan Z

Mon May 31 00:00:00 UTC 2021

The contrary functions of lncRNA HOTAIR/miR-17-5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells.

Journal of cellular and molecular medicine

Jia J,Zhan D,Li J,Li Z,Li H,Qian J

Tue Jan 01 00:00:00 UTC 2019

The contrary functions of lncRNA HOTAIR/miR-17-5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells.

Journal of cellular and molecular medicine

Jia J,Zhan D,Li J,Li Z,Li H,Qian J

Tue Jan 01 00:00:00 UTC 2019

Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.

Stem cells international

Rao N,Wang X,Xie J,Li J,Zhai Y,Li X,Fang T,Wang Y,Zhao Y,Ge L

Thu Oct 01 00:00:00 UTC 2020

Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.

The FEBS journal

Wang X,Yin L,Yang L,Zheng Y,Liu S,Yang J,Cui H,Wang H

Sun Dec 01 00:00:00 UTC 2019

Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT.

Oncology reports

Guo Y,Jia Y,Wang S,Liu N,Gao D,Zhang L,Lin Z,Wang S,Kong F,Peng C,Liu Y

Sun Dec 01 00:00:00 UTC 2019

VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.

American journal of translational research

Bhandari A,Guan Y,Xia E,Huang Q,Chen Y

Thu Oct 01 00:00:00 UTC 2020

RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.

Journal of experimental & clinical cancer research : CR

Li Q,Lai Q,He C,Fang Y,Yan Q,Zhang Y,Wang X,Gu C,Wang Y,Ye L,Han L,Lin X,Chen J,Cai J,Li A,Liu S

Thu Aug 01 00:00:00 UTC 2019

RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.

Journal of experimental & clinical cancer research : CR

Li Q,Lai Q,He C,Fang Y,Yan Q,Zhang Y,Wang X,Gu C,Wang Y,Ye L,Han L,Lin X,Chen J,Cai J,Li A,Liu S

Thu Aug 01 00:00:00 UTC 2019

miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.

BMC cancer

Xin H,Wang C,Liu Z

Tue Jan 08 00:00:00 UTC 2019

miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.

BMC cancer

Xin H,Wang C,Liu Z

Tue Jan 08 00:00:00 UTC 2019

miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.

BMC cancer

Xin H,Wang C,Liu Z

Tue Jan 08 00:00:00 UTC 2019

miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.

BMC cancer

Xin H,Wang C,Liu Z

Tue Jan 08 00:00:00 UTC 2019

Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.

Human reproduction (Oxford, England)

Gou Y,Li X,Li P,Zhang H,Xu T,Wang H,Wang B,Ma X,Jiang X,Zhang Z

Mon Apr 01 00:00:00 UTC 2019

SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.

Cancer cell international

Yang Z,Yu W,Huang R,Ye M,Min Z

Wed Aug 23 00:00:00 UTC 2023

SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.

Cancer cell international

Yang Z,Yu W,Huang R,Ye M,Min Z

Wed Aug 23 00:00:00 UTC 2023

Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.

EBioMedicine

Liu Y,Jiang Q,Liu X,Lin X,Tang Z,Liu C,Zhou J,Zhao M,Li X,Cheng Z,Li L,Xie Y,Liu Z,Fang W

Tue Oct 01 00:00:00 UTC 2019

EBioMedicine

Liu Y,Jiang Q,Liu X,Lin X,Tang Z,Liu C,Zhou J,Zhao M,Li X,Cheng Z,Li L,Xie Y,Liu Z,Fang W

Tue Oct 01 00:00:00 UTC 2019

Knockdown of FAM64A suppresses proliferation and migration of breast cancer cells.

Breast cancer (Tokyo, Japan)

Yao Z,Zheng X,Lu S,He Z,Miao Y,Huang H,Chu X,Cai C,Zou F

Fri Nov 01 00:00:00 UTC 2019

Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.

Cancer letters

Wu D,Zhao B,Qi X,Peng F,Fu H,Chi X,Miao QR,Shao S

Sun Apr 01 00:00:00 UTC 2018

Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.

Cancer letters

Wu D,Zhao B,Qi X,Peng F,Fu H,Chi X,Miao QR,Shao S

Sun Apr 01 00:00:00 UTC 2018

The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.

Oncogene

He T,Jin M,Xu C,Ma Z,Wu F,Zhang X

Mon Oct 01 00:00:00 UTC 2018

The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.

Oncogene

He T,Jin M,Xu C,Ma Z,Wu F,Zhang X

Mon Oct 01 00:00:00 UTC 2018

The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.

Carcinogenesis

Wang X,Fang H,Cheng Y,Li L,Sun X,Fu T,Huang P,Zhang A,Feng Z,Li C,Huang X,Li G,Du P,Yang H,Fang X,Li F,Gao Q,Liu B

Thu May 03 00:00:00 UTC 2018

The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.

Carcinogenesis

Wang X,Fang H,Cheng Y,Li L,Sun X,Fu T,Huang P,Zhang A,Feng Z,Li C,Huang X,Li G,Du P,Yang H,Fang X,Li F,Gao Q,Liu B

Thu May 03 00:00:00 UTC 2018

Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys.

Pharmaceutical research

Shen Y,Yu Y,Lai W,Li S,Xu Z,Jin J,Yan X,Xing H,Chen X,Xiong A,Xia C,He J,Hong K

Tue Nov 06 00:00:00 UTC 2018

Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys.

Pharmaceutical research

Shen Y,Yu Y,Lai W,Li S,Xu Z,Jin J,Yan X,Xing H,Chen X,Xiong A,Xia C,He J,Hong K

Tue Nov 06 00:00:00 UTC 2018

Association of doublecortin-like kinase 1 with tumor aggressiveness and poor biochemical recurrence-free survival in prostate cancer.

OncoTargets and therapy

Jiang D,Xiao C,Xian T,Wang L,Mao Y,Zhang J,Pang J

Wed Mar 16 00:00:00 UTC 2022

Association of doublecortin-like kinase 1 with tumor aggressiveness and poor biochemical recurrence-free survival in prostate cancer.

OncoTargets and therapy

Jiang D,Xiao C,Xian T,Wang L,Mao Y,Zhang J,Pang J

Wed Mar 16 00:00:00 UTC 2022

The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).

European journal of pharmacology

Wang Y,Wu Z,Hu L

Wed Sep 05 00:00:00 UTC 2018

E-cadherin and ZEB2 modulate trophoblast cell differentiation during placental development in pigs.

Reproduction (Cambridge, England)

Hong L,Han K,Wu K,Liu R,Huang J,Lunney JK,Zhao S,Yu M

Fri Dec 01 00:00:00 UTC 2017

E-cadherin and ZEB2 modulate trophoblast cell differentiation during placental development in pigs.

Reproduction (Cambridge, England)

Hong L,Han K,Wu K,Liu R,Huang J,Lunney JK,Zhao S,Yu M

Fri Dec 01 00:00:00 UTC 2017

E-cadherin and ZEB2 modulate trophoblast cell differentiation during placental development in pigs.

Reproduction (Cambridge, England)

Hong L,Han K,Wu K,Liu R,Huang J,Lunney JK,Zhao S,Yu M

Fri Dec 01 00:00:00 UTC 2017

E-cadherin and ZEB2 modulate trophoblast cell differentiation during placental development in pigs.

Reproduction (Cambridge, England)

Hong L,Han K,Wu K,Liu R,Huang J,Lunney JK,Zhao S,Yu M

Fri Dec 01 00:00:00 UTC 2017

Crocetin inhibits the proliferation, migration and TGF-β₂-induced epithelial-mesenchymal transition of retinal pigment epithelial cells.

European journal of pharmacology

Wang HF,Ma JX,Shang QL,An JB,Chen HT

Wed Nov 15 00:00:00 UTC 2017

Crocetin inhibits the proliferation, migration and TGF-β₂-induced epithelial-mesenchymal transition of retinal pigment epithelial cells.

European journal of pharmacology

Wang HF,Ma JX,Shang QL,An JB,Chen HT

Wed Nov 15 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: cadherin 1, E-cadherin (epithelial); cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; Cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; cell-CAM 120/80; E-Cadherin; E-cadherin 1; Ecadherin; Epithelial cadherin; Uvomorulin

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Gene Aliases: Arc-1; CD324; CDH1; CDHE; E-cadherin; ECAD; LCAM; UVO

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UniProt ID: (Human) P12830, (Rat) Q9R0T4

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Entrez Gene ID: (Human) 999, (Pig) 100048953, (Rat) 83502

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Function(s)

glycoprotein binding calcium ion binding protein binding beta-catenin binding ankyrin binding GTPase activating protein binding gamma-catenin binding cell adhesion molecule binding cadherin binding involved in cell-cell adhesion protein phosphatase binding protein domain specific binding

Process(es)

in utero embryonic development trophectodermal cell differentiation epithelial cell morphogenesis homophilic cell adhesion via plasma membrane adhesion molecules synapse assembly sensory perception of sound response to toxic substance response to organic substance single organismal cell-cell adhesion calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules protein metabolic process pituitary gland development negative regulation of cell-cell adhesion neuron projection development regulation of protein localization regulation of water loss via skin adherens junction organization response to drug positive regulation of transcription factor import into nucleus regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of transcription, DNA-templated negative regulation of epithelial cell proliferation protein homooligomerization intestinal epithelial cell development salivary gland cavitation regulation of branching involved in salivary gland morphogenesis bicellular tight junction assembly cellular response to amino acid stimulus cellular response to lithium ion cellular response to indole-3-methanol protein localization to plasma membrane establishment of protein localization to plasma membrane negative regulation of canonical Wnt signaling pathway cochlea development regulation of protein localization to cell surface regulation of neuron migration extracellular matrix disassembly extracellular matrix organization

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E-cadherin Monoclonal Antibody (6B11F11)

E-cadherin Antibody (60335-1-IG) in IHC (P)

Product Details

60335-1-IG

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Not applicable (N/A)

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Published species

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Type

Clone

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