Product References
Topography of pleural epithelial structure enabled by en face isolation and machine learning.
Journal of cellular physiology
Liu BS,Valenzuela CD,Mentzer KL,Wagner WL,Khalil HA,Chen Z,Ackermann M,Mentzer SJ
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to conclude that the structured analysis of pleural epithelial cells complements studies of pulmonary microstructure and provides useful insights into the regional distribution of mechanical stresses in the lung.
Sun Jan 01 00:00:00 UTC 2023
Genetic recording of in vivo cell proliferation by ProTracer.
Nature protocols
Liu X,Weng W,He L,Zhou B
13-1900 was used in Immunohistochemistry-immunofluorescence to show that the protocol is applicable to study any in vivo cell proliferation, which takes ~9 months to finish from mouse generation to data analysis.
Sat Jul 01 00:00:00 UTC 2023
Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice.
EBioMedicine
Peres C,Sellitto C,Nardin C,Putti S,Orsini T,Di Pietro C,Marazziti D,Vitiello A,Calistri A,Rigamonti M,Scavizzi F,Raspa M,Zonta F,Yang G,White TW,Mammano F
13-1900 was used in Immunohistochemistry to show that AAVmAb treatment eliminated abnormal keratinocyte proliferation and enlarged cell size, decreased apoptosis, and restored the normal distribution of keratin expression.
Wed Mar 01 00:00:00 UTC 2023
Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer.
EMBO reports
Wu Z,Thierry K,Bachy S,Zhang X,Gamradt P,Hernandez-Vargas H,Mikaelian I,Tonon L,Pommier R,Zhao Y,Bertolino P,Hennino A
13-1900 was used in Immunohistochemistry (Paraffin) to reveal the existence of a cell population that instructs immunosuppressive myeloid cell responses to bypass PD-1 targeting and thus suggest potential new approaches for overcoming resistance to immunotherapy in clinical settings.
Wed Apr 05 00:00:00 UTC 2023
TRPA1 protects mice from pathogenic Citrobacter rodentium infection via maintaining the colonic epithelial barrier function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu L,Xu M,Zhang Z,Qiao Z,Tang Z,Wan F,Lan L
13-1900 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to identify an unrecognized protective role of TRPA1 in host defense against an enteric bacterial pathogen by maintaining colonic epithelium barrier function, at least in part, via preserving the distribution and expression of TJ proteins in CECs.
Wed Feb 01 00:00:00 UTC 2023
Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis.
The Journal of clinical investigation
Reyes EA,Castillo-Azofeifa D,Rispal J,Wald T,Zwick RK,Palikuqi B,Mujukian A,Rabizadeh S,Gupta AR,Gardner JM,Boffelli D,Gartner ZJ,Klein OD
13-1900 was used in Immunohistochemistry to report that the inflammatory cytokine tumor necrosis factor (TNF), generated by the epithelium, contributes to mucin homeostasis by regulating both cell differentiation and cystic fibrosis transmembrane conductance regulator (CFTR) activity.
Mon Oct 16 00:00:00 UTC 2023
Role of Delta/Notch-like EGF-related receptor in blood glucose homeostasis.
Frontiers in endocrinology
Ruiz-Otero N,Kuruvilla R
13-1900 was used in Immunohistochemistry (Frozen) to suggest that DNER plays a crucial role in mediating islet cell-cell interactions and glucose homeostasis.
Mon Jun 12 00:00:00 UTC 2023
Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme.
Nature communications
Alber AB,Marquez HA,Ma L,Kwong G,Thapa BR,Villacorta-Martin C,Lindstrom-Vautrin J,Bawa P,Wang F,Luo Y,Ikonomou L,Shi W,Kotton DN
13-1900 was used in Immunohistochemistry to identify the pathways (RA and Shh) necessary to specify lung mesenchyme and find that mouse iPSC-derived lung mesenchyme (iLM) expresses key molecular and functional features of primary developing lung mesenchyme.
Tue Jun 13 00:00:00 UTC 2023
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling.
The EMBO journal
Sun D,Llora Batlle O,van den Ameele J,Thomas JC,He P,Lim K,Tang W,Xu C,Meyer KB,Teichmann SA,Marioni JC,Jackson SP,Brand AH,Rawlins EL
13-1900 was used in Sample Preparation to establish a new workflow for using primary human organoids to elucidate detailed functional mechanisms underlying normal development and disease.
Wed Nov 02 00:00:00 UTC 2022
Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions.
PLoS biology
Zhang K,Yao E,Chuang E,Chen B,Chuang EY,Volk RF,Hofmann KL,Zaro B,Chuang PT
13-1900 was used in Immunohistochemistry to propose that mechanical force induced by noncanonical Wnt signaling mediates a coordinated alteration in the shape and orientation of a group of epithelial and mesenchymal cells.
Mon Aug 01 00:00:00 UTC 2022
Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.
Nature communications
Igarashi N,Miyata K,Loo TM,Chiba M,Hanyu A,Nishio M,Kawasaki H,Zheng H,Toyokuni S,Kon S,Moriyama K,Fujita Y,Takahashi A
13-1900 was used in Immunohistochemistry to provide evidence that cellular senescence inhibits cell competition-mediated elimination of oncogenic cells through HGF signaling, suggesting that it may lead to cancer incidence during aging.
Mon Jul 18 00:00:00 UTC 2022
Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting.
Cell reports
Lewis AE,Kuwahara A,Franzosi J,Bush JO
13-1900 was used in Immunohistochemistry to demonstrate that NKX2-1 coordinates tracheal specification with tissue separation through the regulation of EPHRIN-B2 and tracheoesophageal cell sorting.
Tue Mar 15 00:00:00 UTC 2022
Ultrastructural characteristics of finger-like membrane protrusions in cell competition.
Microscopy (Oxford, England)
Kamasaki T,Uehara R,Fujita Y
13-1900 was used in Immunocytochemistry to suggest that the dynamic reorganization of intercellular adhesions via finger-like protrusions may positively control cell competition between normal and RasV12-transformed cells.
Mon Aug 01 00:00:00 UTC 2022
Nanoarchitecture and molecular interactions of epithelial cell junction proteins revealed by super-resolution microscopy.
Annals of the New York Academy of Sciences
Naser AN,Guiler W,Lu Q,Chen YH
13-1900 was used in Immunocytochemistry to show that STORM reveals regional cellular junction nanoarchitecture previously uncharacterized, providing new insight into potential trans-compartmental modulation of protein functions.
Sat Oct 01 00:00:00 UTC 2022
Nanoarchitecture and molecular interactions of epithelial cell junction proteins revealed by super-resolution microscopy.
Annals of the New York Academy of Sciences
Naser AN,Guiler W,Lu Q,Chen YH
13-1900 was used in Immunocytochemistry to show that STORM reveals regional cellular junction nanoarchitecture previously uncharacterized, providing new insight into potential trans-compartmental modulation of protein functions.
Sat Oct 01 00:00:00 UTC 2022
A novel role for PRL in regulating epithelial cell density by inducing apoptosis at confluence.
Journal of cell science
Lohani S,Funato Y,Akieda Y,Mizutani K,Takai Y,Ishitani T,Miki H
13-1900 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to reveal a novel role for phosphatase of regenerating liver in regulating density-dependent apoptosis in vertebrate epithelia.
Sat Jan 15 00:00:00 UTC 2022
PIM1 promotes hepatic conversion by suppressing reprogramming-induced ferroptosis and cell cycle arrest.
Nature communications
Yuan Y,Wang C,Zhuang X,Lin S,Luo M,Deng W,Zhou J,Liu L,Mao L,Peng W,Chen J,Wang Q,Shu Y,Xue Y,Huang P
13-1900 was used in Immunocytochemistry to develop a trans-omics- based method, central kinase inference, to predict potentially key kinases by integrating quantitative transcriptomic and phosphoproteomic data.
Tue Sep 06 00:00:00 UTC 2022
Transplantation of a human induced pluripotent stem cell-derived airway epithelial cell sheet into the middle ear of rats.
Regenerative therapy
Tada T,Ohnishi H,Yamamoto N,Kuwata F,Hayashi Y,Okuyama H,Morino T,Kasai Y,Kojima H,Omori K
13-1900 was used in Immunocytochemistry to study a novel middle ear mucosal regeneration method by transplanting human induced pluripotent stem cell-derived airway epithelial cells into the middle ear of immunodeficient rats.
Tue Mar 01 00:00:00 UTC 2022
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation.
Nature biomedical engineering
Mead BE,Hattori K,Levy L,Imada S,Goto N,Vukovic M,Sze D,Kummerlowe C,Matute JD,Duan J,Langer R,Blumberg RS,Ordovas-Montanes J,Yilmaz ÖH,Karp JM,Shalek AK
13-1900 was used in Immunohistochemistry to show that druggable biological targets and small-molecule regulators of intestinal stem cell differentiation can be identified via multiplexed phenotypic screening using thousands of miniaturized organoid models of intestinal stem cell differentiation into Paneth cells, and validated via longitudinal single-cell RNA-sequencing.
Fri Apr 01 00:00:00 UTC 2022
Adult Mouse Kidney Stem Cells Orchestrate the De Novo Assembly of a Nephron via Sirt2-Modulated Canonical Wnt/β-Catenin Signaling.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Han X,Sun Z
13-1900 was used in Immunohistochemistry to isolate adult kidney Sca1+ Oct4+ stem/progenitor cells.
Sun May 01 00:00:00 UTC 2022
Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation.
The Journal of clinical investigation
Taguchi K,Elias BC,Sugahara S,Sant S,Freedman BS,Waikar SS,Pozzi A,Zent R,Harris RC,Parikh SM,Brooks CR
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to demonstrate that global deletion of CG1 inhibits G2/M arrest and fibrosis.
Thu Dec 01 00:00:00 UTC 2022
Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation.
The Journal of clinical investigation
Taguchi K,Elias BC,Sugahara S,Sant S,Freedman BS,Waikar SS,Pozzi A,Zent R,Harris RC,Parikh SM,Brooks CR
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to demonstrate that global deletion of CG1 inhibits G2/M arrest and fibrosis.
Thu Dec 01 00:00:00 UTC 2022
Patterning the embryonic pulmonary mesenchyme.
iScience
Goodwin K,Jaslove JM,Tao H,Zhu M,Hopyan S,Nelson CM
13-1900 was used in Immunohistochemistry-immunofluorescence to uncover the principles of pulmonary mesenchymal patterning and identifies a morphogenetically active mesenchymal layer that sculpts the airway epithelium.
Fri Mar 18 00:00:00 UTC 2022
Aerocyte specification and lung adaptation to breathing is dependent on alternative splicing changes.
Life science alliance
Fidalgo MF,Fonseca CG,Caldas P,Raposo AA,Balboni T,Henao-Mišíková L,Grosso AR,Vasconcelos FF,Franco CA
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to reveal that the cell type-specific regulation of lt;igt;Vegfalt;/igt; alternative splicing just before birth modulates the epithelial-endothelial crosstalk in the developing alveoli to promote lung adaptation to breathing.
Tue Oct 11 00:00:00 UTC 2022
Intermediary Role of Lung Alveolar Type 1 Cells in Epithelial Repair upon Sendai Virus Infection.
American journal of respiratory cell and molecular biology
Hernandez BJ,Cain MP,Lynch AM,Flores JR,Tuvim MJ,Dickey BF,Chen J
13-1900 was used in Immunohistochemistry to highlight the hitherto unappreciated role of AT1 cells in lung injury-repair.
Thu Sep 01 00:00:00 UTC 2022
A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates.
Cell
He P,Lim K,Sun D,Pett JP,Jeng Q,Polanski K,Dong Z,Bolt L,Richardson L,Mamanova L,Dabrowska M,Wilbrey-Clark A,Madissoon E,Tuong ZK,Dann E,Suo C,Goh I,Yoshida M,Nikolić MZ,Janes SM,He X,Barker RA,Teichmann SA,Marioni JC,Meyer KB,Rawlins EL
13-1900 was used in Immunohistochemistry (PFA fixed) to identify developmental-specific secretory progenitors and a subtype of neuroendocrine cell related to human small cell lung cancer.
Thu Dec 08 00:00:00 UTC 2022
Regionally distinct trophoblast regulate barrier function and invasion in the human placenta.
eLife
Marsh B,Zhou Y,Kapidzic M,Fisher S,Blelloch R
13-1900 was used in Immunohistochemistry (Frozen) to compare and distinguish cell types and molecular programs between villous chorion and smooth chorion in the second trimester human placenta.
Thu Jul 07 00:00:00 UTC 2022
Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel.
Science advances
Li J,Sudiwala S,Berthoin L,Mohabbat S,Gaylord EA,Sinada H,Cruz Pacheco N,Chang JC,Jeon O,Lombaert IMA,May AJ,Alsberg E,Bahney CS,Knox SM
13-1900 was used in Immunohistochemistry-immunofluorescence to reveal a previously unknown regenerative approach for restoring epithelial organ structure and function that has extensive implications for human patients.
Wed Dec 21 00:00:00 UTC 2022
Imaging Blood Vessels and Lymphatics in Mouse Trachea Wholemounts.
Methods in molecular biology (Clifton, N.J.)
Baluk P,McDonald DM
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to describe practical immunohistochemical methods for fluorescence and confocal microscopy of wholemounts of the mouse trachea to achieve this purpose in which the entire vasculature can be visualized from the organ level to the cellular and subcellular level.
Thu Mar 31 00:00:00 UTC 2022
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
Nature
Pastushenko I,Mauri F,Song Y,de Cock F,Meeusen B,Swedlund B,Impens F,Van Haver D,Opitz M,Thery M,Bareche Y,Lapouge G,Vermeersch M,Van Eycke YR,Balsat C,Decaestecker C,Sokolow Y,Hassid S,Perez-Bustillo A,Agreda-Moreno B,Rios-Buceta L,Jaen P,Redondo P,Sieira-Gil R,Millan-Cayetano JF,Sanmatrtin O,D'Haene N,Moers V,Rozzi M,Blondeau J,Lemaire S,Scozzaro S,Janssens V,De Troya M,Dubois C,Pérez-Morga D,Salmon I,Sotiriou C,Helmbacher F,Blanpain C
13-1900 was used in Immunohistochemistry, Immunocytochemistry to demonstrate that deletion of Fat1, which encodes a protocadherin, promotes malignant progression by controlling cell polarity and adhesion between tumour cells, and between tumour cells and the extracellular matrix.
Fri Jan 01 00:00:00 UTC 2021
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
Nature
Pastushenko I,Mauri F,Song Y,de Cock F,Meeusen B,Swedlund B,Impens F,Van Haver D,Opitz M,Thery M,Bareche Y,Lapouge G,Vermeersch M,Van Eycke YR,Balsat C,Decaestecker C,Sokolow Y,Hassid S,Perez-Bustillo A,Agreda-Moreno B,Rios-Buceta L,Jaen P,Redondo P,Sieira-Gil R,Millan-Cayetano JF,Sanmatrtin O,D'Haene N,Moers V,Rozzi M,Blondeau J,Lemaire S,Scozzaro S,Janssens V,De Troya M,Dubois C,Pérez-Morga D,Salmon I,Sotiriou C,Helmbacher F,Blanpain C
13-1900 was used in Immunohistochemistry, Immunocytochemistry to demonstrate that deletion of Fat1, which encodes a protocadherin, promotes malignant progression by controlling cell polarity and adhesion between tumour cells, and between tumour cells and the extracellular matrix.
Fri Jan 01 00:00:00 UTC 2021
Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion.
Cell
Wang S,Matsumoto K,Lish SR,Cartagena-Rivera AX,Yamada KM
13-1900 was used in Western Blot to reveal that budding morphogenesis is driven by expansion and folding of a distinct epithelial surface cell sheet characterized by strong cell-matrix adhesions and weak cell-cell adhesions.
Thu Jul 08 00:00:00 UTC 2021
Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration.
Nature cell biology
Pérez-González C,Ceada G,Greco F,Matejčić M,Gómez-González M,Castro N,Menendez A,Kale S,Krndija D,Clark AG,Gannavarapu VR,Álvarez-Varela A,Roca-Cusachs P,Batlle E,Vignjevic DM,Arroyo M,Trepat X
13-1900 was used in Immunohistochemistry to provide high-resolution dynamic maps of cell-ECM and cell-cell forces exerted by the intestinal epithelium.
Thu Jul 01 00:00:00 UTC 2021
A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast.
The EMBO journal
Pal B,Chen Y,Vaillant F,Capaldo BD,Joyce R,Song X,Bryant VL,Penington JS,Di Stefano L,Tubau Ribera N,Wilcox S,Mann GB,Papenfuss AT,Lindeman GJ,Smyth GK,Visvader JE
13-1900 was used in Immunohistochemistry to examine global changes in breast heterogeneity across different states.
Tue Jun 01 00:00:00 UTC 2021
The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia.
Current biology : CB
Kozawa K,Sekai M,Ohba K,Ito S,Sako H,Maruyama T,Kakeno M,Shirai T,Kuromiya K,Kamasaki T,Kohashi K,Tanaka S,Ishikawa S,Sato N,Asano S,Suzuki H,Tanimura N,Mukai Y,Gotoh N,Tanino M,Tanaka S,Natsuga K,Soga T,Nakamura T,Yabuta Y,Saitou M,Ito T,Matsuura K,Tsunoda M,Kikumori T,Iida T,Mizutani Y,Miyai Y,Kaibuchi K,Enomoto A,Fujita Y
13-1900 was used in Western Blotting to suggest that CD44 and COL17A1 are crucial regulators for the clonal expansion of transformed cells within multilayered epithelia, thus being potential targets for early diagnosis and preventive treatment for precancerous lesions.
Mon Jul 26 00:00:00 UTC 2021
Cellular dormancy in minimal residual disease following targeted therapy.
Breast cancer research : BCR
Ruth JR,Pant DK,Pan TC,Seidel HE,Baksh SC,Keister BA,Singh R,Sterner CJ,Bakewell SJ,Moody SE,Belka GK,Chodosh LA
13-1900 was used in Immunohistochemistry to identify residual tumour cell-specific features using transgenic mouse models.
Fri Jun 04 00:00:00 UTC 2021
Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength.
Development (Cambridge, England)
Kong JH,Young CB,Pusapati GV,Espinoza FH,Patel CB,Beckert F,Ho S,Patel BB,Gabriel GC,Aravind L,Bazan JF,Gunn TM,Lo CW,Rohatgi R
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to find that mutations and teratogens interact in predictable ways to cause birth defects by changing target cell sensitivity to Hedgehog (Hh) ligands.
Fri Oct 01 00:00:00 UTC 2021
Negative Transpulmonary Pressure Disrupts Airway Morphogenesis by Suppressing Fgf10.
Frontiers in cell and developmental biology
Stanton AE,Goodwin K,Sundarakrishnan A,Jaslove JM,Gleghorn JP,Pavlovich AL,Nelson CM
13-1900 was used in Immunohistochemistry to study the effect of transpulmonary pressure on Fgf10 in congenital lung defects.
Thu May 12 00:00:00 UTC 2022
Asynchrony of Apical Polarization, Luminogenesis, and Functional Differentiation in the Developing Thyroid Gland.
Frontiers in endocrinology
Johansson E,Liang S,Moccia C,Carlsson T,Andersson D,Fagman H,Nilsson M
13-1900 was used in Immunohistochemistry to elucidate whether cells committed to a thyroid fate might be triggered to differentiate asynchronously related to maturation and developmental stage.
Wed Feb 16 00:00:00 UTC 2022
Three-dimensional geometry controls division symmetry in stem cell colonies.
Journal of cell science
Chaigne A,Smith MB,Lopez Cavestany R,Hannezo E,Chalut KJ,Paluch EK
13-1900 was used in Immunocytochemistry to the investigate if in 3D contexts, the geometry of the cell and its contacts with neighbors control division orientation and symmetry.
Thu Jul 15 00:00:00 UTC 2021
The long non-coding RNA ET-20 mediates EMT by impairing desmosomes in breast cancer cells.
Journal of cell science
Saxena M,Hisano M,Neutzner M,Diepenbruck M,Ivanek R,Sharma K,Kalathur RKR,Bürglin TR,Risoli S,Christofori G
13-1900 was used in Immunocytochemistry-immunoflourescence to indicate that targeting ET-20 appears to be a therapeutically attractive lead to restrain EMT and breast cancer metastasis in addition to its potential utility as a biomarker for invasive breast cancer.
Mon Nov 01 00:00:00 UTC 2021
The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.
Journal of cell science
Yazlovitskaya EM,Plosa E,Bock F,Viquez OM,Mernaugh G,Gewin LS,De Arcangelis A,Georges-Labouesse E,Sonnenberg A,Blackwell TS,Pozzi A,Zent R
13-1900 was used in Immunohistochemistry to suggest that laminin-binding integrins play a key role in the maintenance of kidney tubule epithelial cell polarity and decrease pro-inflammatory cytokine secretion by regulating NF-κB-dependent signaling.
Wed Dec 15 00:00:00 UTC 2021
Hair Follicle Grafting Therapy Promotes Re-Emergence of Critical Skin Components in Chronic Nonhealing Wounds.
JID innovations : skin science from molecules to population health
Saha D,Thannimangalath S,Budamakuntla L,Loganathan E,Jamora C
13-1900 was used in Immunohistochemistry to show that the observation that punch wounds created on the postgrafted area likewise healed suggests that this is a self-sustaining long-term therapy for patients with chronic wounds.
Wed Sep 01 00:00:00 UTC 2021
FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells.
iScience
Kamasaki T,Miyazaki Y,Ishikawa S,Hoshiba K,Kuromiya K,Tanimura N,Mori Y,Tsutsumi M,Nemoto T,Uehara R,Suetsugu S,Itoh T,Fujita Y
13-1900 was used in Immunocytochemistry to show that the cdc42/FBP17 pathway induces characteristic protrusive structures at the interface between normal and RasV12 cells, which would play a positive role in the apical extrusion of RasV12 cells from epithelia.
Fri Sep 24 00:00:00 UTC 2021
Lin28 paralogs regulate lung branching morphogenesis.
Cell reports
Osborne JK,Kinney MA,Han A,Akinnola KE,Yermalovich AV,Vo LT,Pearson DS,Sousa PM,Ratanasirintrawoot S,Tsanov KM,Barragan J,North TE,Metzger RJ,Daley GQ
13-1900 was used in Western Blotting to study the role of the Lin28a and Lin28b paralogs during the developmental process of branching morphogenesis.
Tue Jul 20 00:00:00 UTC 2021
TRIP6 is required for tension at adherens junctions.
Journal of cell science
Venkatramanan S,Ibar C,Irvine KD
13-1900 was used in Immunocytochemistry to identify a role for TRIP6 in organizing F-actin and maintaining tension at adherens junctions that could account for its influence on LIMD1 and LATS.
Thu Mar 11 00:00:00 UTC 2021
Molecular neural crest cell markers enable discrimination of organophosphates in the murine cardiac embryonic stem cell test.
Toxicology reports
Mennen RH,Hallmark N,Pallardy M,Bars R,Tinwell H,Piersma AH
13-1900 was used in Immunocytochemistry to explore molecular markers of neural crest cells to improve discrimination between structurally related chemicals, using the three organophosphates (OP): chlorpyrifos (CPF), malathion (MLT), and triphenyl phosphate (TPP).
Wed Aug 18 00:00:00 UTC 2021
Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion.
Nature communications
Junqueira Alves C,Dariolli R,Haydak J,Kang S,Hannah T,Wiener RJ,DeFronzo S,Tejero R,Gusella GL,Ramakrishnan A,Alves Dias R,Wojcinski A,Kesari S,Shen L,Sobie EA,Rodrigues Furtado de Mendonça JP,Azeloglu EU,Zou H,Friedel RH
13-1900 was used in Immunocytochemistry to establish a significant function of Plexin-B2 in orchestrating cytoskeletal tension and cell-cell/cell-matrix adhesion, therefore solidifying the importance of collective cell mechanics in governing stem cell physiology and tissue morphogenesis.
Thu Oct 14 00:00:00 UTC 2021
Stalling interkinetic nuclear migration in curved pseudostratified epithelium of developing cochlea.
Royal Society open science
Ishii M,Tateya T,Matsuda M,Hirashima T
13-1900 was used in Immunohistochemistry-immunofluorescence to report that nuclear behaviour changes are associated with the curvature of the pseudostratified epithelium during murine cochlear development.
Wed Dec 01 00:00:00 UTC 2021
A functional genetic toolbox for human tissue-derived organoids.
eLife
Sun D,Evans L,Perrone F,Sokleva V,Lim K,Rezakhani S,Lutolf M,Zilbauer M,Rawlins EL
13-1900 was used in Immunohistochemistry to facilitate gene perturbation studies in tissue-derived organoids facilitating human disease modelling and providing a counterpart to many ongoing descriptive studies, such as the Human Cell Atlas Project.
Wed Oct 06 00:00:00 UTC 2021
Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition.
Cell reports
Molè MA,Weberling A,Fässler R,Campbell A,Fishel S,Zernicka-Goetz M
13-1900 was used in Immunohistochemistry to study integrin β1 signaling, as embryos deficient for this receptor degenerate at implantation.
Tue Mar 09 00:00:00 UTC 2021
Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH.
Nature protocols
Messal HA,Almagro J,Zaw Thin M,Tedeschi A,Ciccarelli A,Blackie L,Anderson KI,Miguel-Aliaga I,van Rheenen J,Behrens A
13-1900 was used in Western Blot to describe FLASH (fast light-microscopic analysis of antibody-stained whole organs), a simple, rapid, fully customizable technique for molecular phenotyping of intact tissue volumes.
Fri Jan 01 00:00:00 UTC 2021
Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis.
eLife
Ishii M,Tateya T,Matsuda M,Hirashima T
13-1900 was used in Immunohistochemistry to study the regulation of ERK in mammalian cochlear ducts with deep tissue live-cell imaging and FRET.
Fri Mar 05 00:00:00 UTC 2021
Septum submucosal glands exhibit aberrant morphology and reduced mucin production in chronic rhinosinusitis.
International forum of allergy & rhinology
Nnabue OE,Pletcher SD,Gurrola JG,Goldberg AN,Jordan KM,Knox SM,May AJ
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to describe a significant alteration in SMG structure and function in the adult CRS posterior septum suggesting reduced gland contribution to MCC.
Fri Oct 01 00:00:00 UTC 2021
Trophectoderm mechanics direct epiblast shape upon embryo implantation.
Cell reports
Weberling A,Zernicka-Goetz M
13-1900 was used in Immunohistochemistry to show that the first extraembryonic lineage, the polar trophectoderm, is the key regulator for remodeling the embryonic epiblast.
Tue Jan 19 00:00:00 UTC 2021
Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation.
Molecular cancer
Weiße J,Rosemann J,Müller L,Kappler M,Eckert AW,Glaß M,Misiak D,Hüttelmaier S,Ballhausen WG,Hatzfeld M,Haemmerle M,Gutschner T
13-1900 was used in Immunocytochemistry to show that reduction of LCK activity increased the formation of adherens junctions and induced cell differentiation.
Fri Jun 11 00:00:00 UTC 2021
Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation.
eLife
Katsuno-Kambe H,Teo JL,Ju RJ,Hudson J,Stehbens SJ,Yap AS
13-1900 was used in Immunocytochemistry to focus on understanding cellular mechanisms for elongation using an organotypic culture system as a model of mammary epithelial anlage.
Mon Oct 18 00:00:00 UTC 2021
Basement membrane remodelling regulates mouse embryogenesis.
Nature
Kyprianou C,Christodoulou N,Hamilton RS,Nahaboo W,Boomgaard DS,Amadei G,Migeotte I,Zernicka-Goetz M
13-1900 was used in Immunocytochemistry to show that Nodal signalling directs the generation and dynamic distribution of perforations in the basement membrane by regulating the expression of matrix metalloproteinases.
Mon Jun 01 00:00:00 UTC 2020
Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer Drivers.
Cell stem cell
Ying Z,Beronja S
13-1900 was used in Immunohistochemistry to demonstrate the lentiviral injection-mediated transduction of progenitors to adult mammary gland cells for the study of breast cancer drivers.
Thu Mar 05 00:00:00 UTC 2020
Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis.
Cell stem cell
Chang W,Wang H,Kim W,Liu Y,Deng H,Liu H,Jiang Z,Niu Z,Sheng W,Nápoles OC,Sun Y,Xu J,Sepulveda A,Hayakawa Y,Bass AJ,Wang TC
13-1900 was used in Immunohistochemistry to show that gastric tumorigenesis is associated with increased symmetric cell division that facilitates mutation and is suppressed by GPCR signaling.
Thu May 07 00:00:00 UTC 2020
Oncogenic Signaling Alters Cell Shape and Mechanics to Facilitate Cell Division under Confinement.
Developmental cell
Matthews HK,Ganguli S,Plak K,Taubenberger AV,Win Z,Williamson M,Piel M,Guck J,Baum B
13-1900 was used in Western Blot to investigate the effect of oncogene activation on the process of normal epithelial cell diving into tissue.
Mon Mar 09 00:00:00 UTC 2020
DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation.
Developmental cell
Seldin L,Macara IG
13-1900 was used in Immunohistochemistry to conclude that genotoxic agents that are used chemotherapeutically to promote cancer cell death can have the opposite effect on wild-type epithelia by inducing, via a non-autonomous IL-1β-driven mechanism, both hyperplasia and stem cell lineage defects.
Mon Dec 07 00:00:00 UTC 2020
A Pygopus 2-Histone Interaction Is Critical for Cancer Cell Dedifferentiation and Progression in Malignant Breast Cancer.
Cancer research
Saxena M,Kalathur RKR,Rubinstein N,Vettiger A,Sugiyama N,Neutzner M,Coto-Llerena M,Kancherla V,Ercan C,Piscuoglio S,Fischer J,Fagiani E,Cantù C,Basler K,Christofori G
13-1900 was used in Immunocytochemistry to show that Pygo2 represents a potential therapeutic target in metastatic breast cancer, as its histone-binding capability promotes β-catenin-mediated Wnt signaling and transcriptional control in breast cancer cell dedifferentiation, EMT, and metastasis.
Tue Sep 01 00:00:00 UTC 2020
Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.
Proceedings of the National Academy of Sciences of the United States of America
Gerner-Mauro KN,Akiyama H,Chen J
13-1900 was used in Flow cytometry/Cell sorting to generate two quadruple conditional knockouts, four triple mutants, and various combinations of double mutants, showing that the four Lef/Tcf genes function redundantly in the presence of at least two Lef/Tcf paralogs, but additively upon losing additional paralogs to specify and maintain lung epithelial progenitors., using the developing mouse lung as a model system.
Tue Jun 02 00:00:00 UTC 2020
Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice.
British journal of pharmacology
Goldblatt DL,Flores JR,Valverde Ha G,Jaramillo AM,Tkachman S,Kirkpatrick CT,Wali S,Hernandez B,Ost DE,Scott BL,Chen J,Evans SE,Tuvim MJ,Dickey BF
13-1900 was used in Immunohistochemistry-immunofluorescence to suggest that treatment of susceptible human hosts with aerosolized ODN and Pam2 at the time of a respiratory viral infection might attenuate the severity of the acute infection and reduce initiation, exacerbation and progression of asthma.
Fri May 01 00:00:00 UTC 2020
GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.
The Journal of cell biology
Lucken-Ardjomande Häsler S,Vallis Y,Pasche M,McMahon HT
13-1900 was used in Immunocytochemistry-immunoflourescence to find extensive colocalization of GRAF1b/2 with Rab8a/b and partial with Rab10.
Mon May 04 00:00:00 UTC 2020
RAB6 GTPase regulates mammary secretory function by controlling the activation of STAT5.
Development (Cambridge, England)
Cayre S,Faraldo MM,Bardin S,Miserey-Lenkei S,Deugnier MA,Goud B
13-1900 was used in Immunohistochemistry-immunofluorescence to reveal a crucial role for RAB6A/A' in the lactogenic function of the mammary gland and suggest that the trafficking pathways controlled by RAB6A/A' depend on cell-type specialization and tissue context.
Thu Oct 08 00:00:00 UTC 2020
Disruption of the nectin-afadin complex recapitulates features of the human cleft lip/palate syndrome CLPED1.
Development (Cambridge, England)
Lough KJ,Spitzer DC,Bergman AJ,Wu JJ,Byrd KM,Williams SE
13-1900 was used in Immunohistochemistry to provide the first direct evidence that the nectin-afadin axis is essential for proper palate shelf elevation and fusion.
Mon Jul 13 00:00:00 UTC 2020
Molecular and genetic regulation of pig pancreatic islet cell development.
Development (Cambridge, England)
Kim S,Whitener RL,Peiris H,Gu X,Chang CA,Lam JY,Camunas-Soler J,Park I,Bevacqua RJ,Tellez K,Quake SR,Lakey JRT,Bottino R,Ross PJ,Kim SK
13-1900 was used in Immunohistochemistry (Frozen) to investigate fetal and neonatal pig pancreas at multiple, crucial developmental stages using modern experimental approaches.
Mon Mar 30 00:00:00 UTC 2020
Proteomic analysis of desmosomes reveals novel components required for epidermal integrity.
Molecular biology of the cell
Badu-Nkansah KA,Lechler T
13-1900 was used in Immunocytochemistry-Immunofluorescence to target proximity labeling approaches to further elaborate the desmosome proteome in epidermal keratinocytes.
Fri May 15 00:00:00 UTC 2020
Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion.
Molecular biology of the cell
Teo JL,Tomatis VM,Coburn L,Lagendijk AK,Schouwenaar IM,Budnar S,Hall TE,Verma S,McLachlan RW,Hogan BM,Parton RG,Yap AS,Gomez GA
13-1900 was used in Immunocytochemistry to report a complementary process of cytoskeletal relaxation that occurs when cortical contractility is down-regulated at the junctions between those neighbor cells themselves.
Sun Nov 01 00:00:00 UTC 2020
Going Back and Forth: Episomal Vector Reprogramming of Peripheral Blood Mononuclear Cells to Induced Pluripotent Stem Cells and Subsequent Differentiation into Cardiomyocytes and Neuron-Astrocyte Co-cultures.
Cellular reprogramming
de Leeuw VC,van Oostrom CTM,Imholz S,Piersma AH,Hessel EVS,Dollé MET
13-1900 was used in Immunocytochemistry to reprogramme PBMCs into iPSCs and studied their pluripotent nature.
Tue Dec 01 00:00:00 UTC 2020
YAP/TAZ Regulate Elevation and Bone Formation of the Mouse Secondary Palate.
Journal of dental research
Goodwin AF,Chen CP,Vo NT,Bush JO,Klein OD
13-1900 was used in Immunomicroscopy to suggest that YAP/TAZ may regulate collagen crosslinking in the palatal shelf mesenchyme, thus controlling palatal shelf elevation, as well as mineralization of the bones of the secondary palate.
Sun Nov 01 00:00:00 UTC 2020
Single nuclei RNA-seq of mouse placental labyrinth development.
eLife
Marsh B,Blelloch R
13-1900 was used in Immunocytochemistry to study the ontogeny, specification, and function of the cell types of a representative hemochorial placenta.
Tue Nov 03 00:00:00 UTC 2020
Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins.
PloS one
Oparija-Rogenmozere L,Rajendran A,Poncet N,Camargo SMR,Verrey F
13-1900 was used in Western Blotting to show that phosphorylation, expression and localization of intestinal mouse LAT4 responds to diurnal and dietary stimuli in location-specific manner.
Mon Aug 17 00:00:00 UTC 2020
Multi-lineage Lung Regeneration by Stem Cell Transplantation across Major Genetic Barriers.
Cell reports
Hillel-Karniel C,Rosen C,Milman-Krentsis I,Orgad R,Bachar-Lustig E,Shezen E,Reisner Y
13-1900 was used in Immunohistochemistry to lay the foundation for repair of lung injury through a procedure akin to bone marrow transplantation.
Tue Jan 21 00:00:00 UTC 2020
Alterations in corneal biomechanics underlie early stages of autoimmune-mediated dry eye disease.
Journal of autoimmunity
Efraim Y,Chen FYT,Stashko C,Cheong KN,Gaylord E,McNamara N,Knox SM
13-1900 was used in Immunohistochemistry to reveal novel perturbations in corneal biomechanics, matrix organization and cell behavior during the early phase of dry eye that may underlie disease development and progression, presenting new potential targets for therapeutic intervention.
Sun Nov 01 00:00:00 UTC 2020
Distal lung epithelial progenitor cell function declines with age.
Scientific reports
Watson JK,Sanders P,Dunmore R,Rosignoli G,Julé Y,Rawlins EL,Mustelin T,May R,Clarke D,Finch DK
13-1900 was used in Immunohistochemistry to elucidate how they contribute to age-related loss of pulmonary function, and pathogenesis of common age-related pulmonary diseases.
Fri Jun 26 00:00:00 UTC 2020
mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division.
Nature communications
Bonucci M,Kuperwasser N,Barbe S,Koka V,de Villeneuve D,Zhang C,Srivastava N,Jia X,Stokes MP,Bienaimé F,Verkarre V,Lopez JB,Jaulin F,Pontoglio M,Terzi F,Delaval B,Piel M,Pende M
13-1900 was used in Immunohistochemistry to reveal that S6K1 hyperactivity alters centrosome positioning in mitotic cells, affecting oriented cell division and promoting kidney cysts in conditions of mTOR hyperactivity.
Wed Jun 24 00:00:00 UTC 2020
Incoherent Feedforward Regulation via Sox9 and ERK Underpins Mouse Tracheal Cartilage Development.
Frontiers in cell and developmental biology
Yoshida T,Matsuda M,Hirashima T
13-1900 was used in Immunohistochemistry to show a core regulatory network underlying murine tracheal chondrogenesis from embryonic day (E) 12.5 to E15.5, by combining volumetric imaging of fluorescence reporters, inhibitor assays, and mathematical modeling.
Tue Nov 17 00:00:00 UTC 2020
Reciprocal Signaling between Myeloid Derived Suppressor and Tumor Cells Enhances Cellular Motility and is Mediated by Structural Cues in the Microenvironment.
Advanced biosystems
Shukla VC,Duarte-Sanmiguel S,Panic A,Senthilvelan A,Moore J,Bobba C,Benner B,Carson WE,Ghadiali SN,Gallego-Perez D
13-1900 was used in Immunocytochemistry to investigate the biochemical and biostructural conditions under which myeloid derived suppressor cells can support cancer cell migration.
Mon Jun 01 00:00:00 UTC 2020
E-cadherin is required for metastasis in multiple models of breast cancer.
Nature
Padmanaban V,Krol I,Suhail Y,Szczerba BM,Aceto N,Bader JS,Ewald AJ
13-1900 was used in Western Blot to test the genetic requirement for E-cadherin in metastasis using mouse and human models of both luminal and basal invasive ductal carcinomas.
Sun Sep 01 00:00:00 UTC 2019
Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch.
Cell
Ouadah Y,Rojas ER,Riordan DP,Capostagno S,Kuo CS,Krasnow MA
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to propose that neuroendocrine stem cells give rise to small cell lung cancer, and transformation results from constitutive activation of stem cell renewal and inhibition of deprogramming.
Thu Oct 03 00:00:00 UTC 2019
Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.
Cancer cell
Rios AC,Capaldo BD,Vaillant F,Pal B,van Ineveld R,Dawson CA,Chen Y,Nolan E,Fu NY,Jackling FC,Devi S,Clouston D,Whitehead L,Smyth GK,Mueller SN,Lindeman GJ,Visvader JE
13-1900 was used in Western Blotting to develop a 3D imaging protocol based on a rapid clearing agent termed FUnGI that enables large-scale imaging of intact solid tumors.
Mon Apr 15 00:00:00 UTC 2019
Smooth muscle differentiation shapes domain branches during mouse lung development.
Development (Cambridge, England)
Goodwin K,Mao S,Guyomar T,Miller E,Radisky DC,Košmrlj A,Nelson CM
13-1900 was used in Immunohistochemistry-immunofluorescence to shed light on the physical mechanisms of branching morphogenesis in the mouse lung.
Mon Nov 25 00:00:00 UTC 2019
GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73.
Journal of cell science
Lalioti ME,Arbi M,Loukas I,Kaplani K,Kalogeropoulou A,Lokka G,Kyrousi C,Mizi A,Georgomanolis T,Josipovic N,Gkikas D,Benes V,Politis PK,Papantonis A,Lygerou Z,Taraviras S
13-1900 was used in Immunohistochemistry to highlight novel signaling cues involved in the commitment program of MCCs across species and tissues.
Mon Jun 03 00:00:00 UTC 2019
Cutaneous Epithelial to Mesenchymal Transition Activator ZEB1 Regulates Wound Angiogenesis and Closure in a Glycemic Status-Dependent Manner.
Diabetes
Singh K,Sinha M,Pal D,Tabasum S,Gnyawali SC,Khona D,Sarkar S,Mohanty SK,Soto-Gonzalez F,Khanna S,Roy S,Sen CK
13-1900 was used in Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry to propose ZEB1 as a key regulator of cutaneous wound healing that is of particular relevance to diabetic wound complication.
Fri Nov 01 00:00:00 UTC 2019
Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation.
Nature communications
Christodoulou N,Weberling A,Strathdee D,Anderson KI,Timpson P,Zernicka-Goetz M
13-1900 was used in Immunohistochemistry-immunofluorescence to determine the cellular and molecular mechanism underlying mammalian embryo shape change upon implantation.
Wed Aug 07 00:00:00 UTC 2019
Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.
Nature communications
Schipper K,Seinstra D,Paulien Drenth A,van der Burg E,Ramovs V,Sonnenberg A,van Rheenen J,Nethe M,Jonkers J
13-1900 was used in Western Blotting to unmask the direct consequences of E-cadherin inactivation in the mammary gland and identify aberrant actomyosin contractility as a critical barrier to ILC formation.
Fri Aug 23 00:00:00 UTC 2019
Telophase correction refines division orientation in stratified epithelia.
eLife
Lough KJ,Byrd KM,Descovich CP,Spitzer DC,Bergman AJ,Beaudoin GM,Reichardt LF,Williams SE
13-1900 was used in Immunohistochemistry to identify orientation mechanisms of spindle orientations during early mitosis.
Fri Dec 13 00:00:00 UTC 2019
TANK-binding kinase 1 is a mediator of platelet-induced EMT in mammary carcinoma cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Y,Unnithan RVM,Hamidi A,Caja L,Saupe F,Moustakas A,Cedervall J,Olsson AK
13-1900 was used in Immunocytochemistry to suggest that TBK1 contributes to tumor invasiveness and may be a driver of metastatic spread in breast cancer.
Mon Jul 01 00:00:00 UTC 2019
Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility.
eLife
Saatcioglu HD,Kano M,Horn H,Zhang L,Samore W,Nagykery N,Meinsohn MC,Hyun M,Suliman R,Poulo J,Hsu J,Sacha C,Wang D,Gao G,Lage K,Oliva E,Morris Sabatini ME,Donahoe PK,Pépin D
13-1900 was used in Immunohistochemistry to determine the role of Misr2+ cells in the uterus.
Mon Jun 24 00:00:00 UTC 2019
Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells.
Science (New York, N.Y.)
Nabhan AN,Brownfield DG,Harbury PB,Krasnow MA,Desai TJ
13-1900 was used in Immunohistochemistry to show that AT2 lung stem cells display active Wnt signaling and many are near single, Wnt-expressing fibroblasts and blocking Wnt secretion depletes these stem cells.
Fri Mar 09 00:00:00 UTC 2018
Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.
EMBO molecular medicine
Emmerson E,May AJ,Berthoin L,Cruz-Pacheco N,Nathan S,Mattingly AJ,Chang JL,Ryan WR,Tward AD,Knox SM
13-1900 was used in Immunohistochemistry-immunofluorescence to establish a new paradigm that salivary glands can regenerate after genotoxic shock and do so through a SOX2 nerve-dependent mechanism.
Thu Mar 01 00:00:00 UTC 2018
Mechanical Forces Program the Orientation of Cell Division during Airway Tube Morphogenesis.
Developmental cell
Tang Z,Hu Y,Wang Z,Jiang K,Zhan C,Marshall WF,Tang N
13-1900 was used in Immunohistochemistry to demonstrate that mechanical forces, cell geometry, and oriented cell division function together in a highly coordinated manner to ensure normal airway tube morphogenesis.
Mon Feb 05 00:00:00 UTC 2018
R-spondin3 Is Associated with Basal-Progenitor Behavior in Normal and Tumor Mammary Cells.
Cancer research
Tocci JM,Felcher CM,García Solá ME,Goddio MV,Zimberlin MN,Rubinstein N,Srebrow A,Coso OA,Abba MC,Meiss RP,Kordon EC
13-1900 was used in Western Blotting to investigate if R-spondin3 could be a potential therapetuic target in basal-like breast cancers.
Wed Aug 15 00:00:00 UTC 2018
β-Catenin is a pH sensor with decreased stability at higher intracellular pH.
The Journal of cell biology
White KA,Grillo-Hill BK,Esquivel M,Peralta J,Bui VN,Chire I,Barber DL
13-1900 was used in Immunohistochemistry to show that Β-catenin stability is regulated by intracellular pH dynamics, functioning in coincidence with phosphorylation.
Mon Nov 05 00:00:00 UTC 2018
Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.
Development (Cambridge, England)
Bresson L,Faraldo MM,Di-Cicco A,Quintanilla M,Glukhova MA,Deugnier MA
13-1900 was used in Western Blotting to reveal a role of transmembrane protein podoplanin as marker of the basal compartment.
Wed Feb 21 00:00:00 UTC 2018
A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.
Development (Cambridge, England)
Ghimire SR,Ratzan EM,Deans MR
13-1900 was used in Immunohistochemistry-immunofluorescence to reveal a non-autonomous function for PCP signaling during axon guidance occurring in the tissue that is innervated, rather than the navigating growth cone.
Thu Jun 14 00:00:00 UTC 2018
Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens.
Differentiation; research in biological diversity
Azimi M,Le TT,Brown NL
13-1900 was used in Immunohistochemistry to study the role of presenilins and downstream Notch signalling in eye tissue development.
Wed Nov 21 00:00:00 UTC 2018
PyMT-1099, a versatile murine cell model for EMT in breast cancer.
Scientific reports
Saxena M,Kalathur RKR,Neutzner M,Christofori G
13-1900 was used in Immunocytochemistry to study and characterise epithelial PyMT-1099 cancer cells from the MMTV-PyMT mouse model of breast cancer and report on processes of epithelial-mesenchymal transition.
Tue Aug 14 00:00:00 UTC 2018
Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence.
Developmental cell
Fu NY,Pal B,Chen Y,Jackling FC,Milevskiy M,Vaillant F,Capaldo BD,Guo F,Liu KH,Rios AC,Lim N,Kueh AJ,Virshup DM,Herold MJ,Tucker HO,Smyth GK,Lindeman GJ,Visvader JE
13-1900 was used in Immunohistochemistry to show that ablation of the transcription factor Foxp1 in the mammary gland profoundly impairs ductal morphogenesis, resulting in a rudimentary tree throughout life.
Mon Dec 03 00:00:00 UTC 2018
Obesity Suppresses Cell-Competition-Mediated Apical Elimination of RasV12-Transformed Cells from Epithelial Tissues.
Cell reports
Sasaki A,Nagatake T,Egami R,Gu G,Takigawa I,Ikeda W,Nakatani T,Kunisawa J,Fujita Y
13-1900 was used in Immunohistochemistry-immunofluorescence to study if high-fat diet (HFD) feeding substantially attenuates the frequency of apical elimination of RasV12-transformed cells from intestinal and pancreatic epithelia in a cell competition mouse model.
Tue Apr 24 00:00:00 UTC 2018
miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer.
Cell death & disease
Yu X,Zhang Y,Cavazos D,Ma X,Zhao Z,Du L,Pertsemlidis A
13-1900 was used in Western Blotting to demonstrate that overexpression or induced expression of miR-195 in lung tumors slows tumor growth and that repression of miR-195 accelerates tumor growth.
Wed Feb 07 00:00:00 UTC 2018
Anxa4 mediated airway progenitor cell migration promotes distal epithelial cell fate specification.
Scientific reports
Jiang K,Tang Z,Li J,Wang F,Tang N
13-1900 was used in Western Blotting to demonstrate ERK1/2/Anxa4 signaling promotes the migration of airway epithelial progenitor cells to distal airway tips and ensures their distal cell fate.
Tue Sep 25 00:00:00 UTC 2018
Automated cell-type classification in intact tissues by single-cell molecular profiling.
eLife
Nagendran M,Riordan DP,Harbury PB,Desai TJ
13-1900 was used in Immunohistochemistry to develop a proximity ligation in situ hybridisation technology with exceptional signal strength, specificity and sensitivity in tissue.
Wed Jan 10 00:00:00 UTC 2018
Type I interferons instigate fetal demise after Zika virus infection.
Science immunology
Yockey LJ,Jurado KA,Arora N,Millet A,Rakib T,Milano KM,Hastings AK,Fikrig E,Kong Y,Horvath TL,Weatherbee S,Kliman HJ,Coyne CB,Iwasaki A
13-1900 was used in Immunohistochemistry to show that type I interferons are a possible mediator of pregnancy complications in context of congenital viral infections.
Fri Jan 05 00:00:00 UTC 2018
Complex bile duct network formation within liver decellularized extracellular matrix hydrogels.
Scientific reports
Lewis PL,Su J,Yan M,Meng F,Glaser SS,Alpini GD,Green RM,Sosa-Pineda B,Shah RN
13-1900 was used in Immunohistochemistry to show phenotypic stability via immunostaining for specific cholangiocyte markers.
Wed Aug 15 00:00:00 UTC 2018
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea.
Nature
Nonomura K,Woo SH,Chang RB,Gillich A,Qiu Z,Francisco AG,Ranade SS,Liberles SD,Patapoutian A
131900 was used in immunohistochemistry - frozen section to report that global and sensory neuron-specific ablation of the mechanically activated ion channel Piezo2 causes respiratory distress and death in newborn mice
Thu Jan 12 00:00:00 UTC 2017
Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells.
Proceedings of the National Academy of Sciences of the United States of America
Saitoh S,Maruyama T,Yako Y,Kajita M,Fujioka Y,Ohba Y,Kasai N,Sugama N,Kon S,Ishikawa S,Hayashi T,Yamazaki T,Tada M,Fujita Y
13-1900 was used in Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry to demonstrate that Rab5-mediated endocytosis is a crucial regulator for the competitive interaction between normal and transformed epithelial cells in mammals.
Tue Mar 21 00:00:00 UTC 2017
Disruption of Core Planar Cell Polarity Signaling Regulates Renal Tubule Morphogenesis but Is Not Cystogenic.
Current biology : CB
Kunimoto K,Bayly RD,Vladar EK,Vonderfecht T,Gallagher AR,Axelrod JD
13-1900 was used in Immunohistochemistry to show that a key function of planar cell polarity involves the regulation of tubule diameter but a loss of control does not induce cysts.
Mon Oct 23 00:00:00 UTC 2017
The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton.
Cancer letters
Platet N,Hinkel I,Richert L,Murdamoothoo D,Moufok-Sadoun A,Vanier M,Lavalle P,Gaiddon C,Vautier D,Freund JN,Gross I
131900 was used in immunocytochemistry to study the mechanism by which CDX2 antagonizes tumor cell dissemination
Wed Feb 01 00:00:00 UTC 2017
Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.
Development (Cambridge, England)
Farmer DT,Nathan S,Finley JK,Shengyang Yu K,Emmerson E,Byrnes LE,Sneddon JB,McManus MT,Tward AD,Knox SM
13-1900 was used in Immunohistochemistry-immunofluorescence to reveal crucial features of lacrimal gland development that have broad implications for understanding epithelial organogenesis.
Sat Jul 01 00:00:00 UTC 2017
Genome-wide identification of regulatory elements in Sertoli cells.
Development (Cambridge, England)
Maatouk DM,Natarajan A,Shibata Y,Song L,Crawford GE,Ohler U,Capel B
13-1900 was used in immunohistochemistry to identify genetic regulatory sites involved in sex determination
Wed Feb 15 00:00:00 UTC 2017
Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.
Development (Cambridge, England)
Mathew S,Palamuttam RJ,Mernaugh G,Ramalingam H,Lu Z,Zhang MZ,Ishibe S,Critchley DR,Fässler R,Pozzi A,Sanders CR,Carroll TJ,Zent R
13-1900 was used in Immunohistochemistry-immunofluorescence to determine the role of talin binding to the B1 proximal NPxY motif in the developing kidney.
Wed Nov 15 00:00:00 UTC 2017
Differentiation of Islet Progenitors Regulated by Nicotinamide into Transcriptome-Verified β Cells That Ameliorate Diabetes.
Stem cells (Dayton, Ohio)
Jiang FX,Li K,Archer M,Mehta M,Jamieson E,Charles A,Dickinson JE,Matsumoto M,Morahan G
131900 was used in flow cytometry to find that the multi-functional molecule nicotinamide is a specific differentiation regulator of mouse islet progenitor cells
Mon May 01 00:00:00 UTC 2017
Circadian Clock Is Involved in Regulation of Hepatobiliary Transport Mediated by Multidrug Resistance-Associated Protein 2.
Journal of pharmaceutical sciences
Oh JH,Lee JH,Han DH,Cho S,Lee YJ
13-1900 was used in Western Blotting to investigate circadian rhythm in the expression and function of multidrug resistance-associated protein 2 in mouse liver and the involvement of the circadian clock genes.
Fri Sep 01 00:00:00 UTC 2017
ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens.
Molecular biology of the cell
Priya R,Liang X,Teo JL,Duszyc K,Yap AS,Gomez GA
131900 was used in immunocytochemistry and western blot to analyze differential functional effects for rho kinases 1 and 2 at the epithelial zonula adherens
Sun Jan 01 00:00:00 UTC 2017
Long Noncoding RNA Moderates MicroRNA Activity to Maintain Self-Renewal in Embryonic Stem Cells.
Stem cell reports
Smith KN,Starmer J,Miller SC,Sethupathy P,Magnuson T
13-1900 was used in Immunocytochemistry to demonstrate that Cryano contributes to embryonic stem cell maintenance, as its depletion results in the loss of hallmarks of self-renewal.
Tue Jul 11 00:00:00 UTC 2017
Gcg CreERT2 knockin mice as a tool for genetic manipulation in pancreatic alpha cells.
Diabetologia
Shiota C,Prasadan K,Guo P,Fusco J,Xiao X,Gittes GK
13-1900 was used in Immunohistochemistry to evaluate the tissue specificity, efficiency and tamoxifen dependency of Gcg CreERT2 -mediated recombination.
Fri Dec 01 00:00:00 UTC 2017
Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids.
eLife
Nikolić MZ,Caritg O,Jeng Q,Johnson JA,Sun D,Howell KJ,Brady JL,Laresgoiti U,Allen G,Butler R,Zilbauer M,Giangreco A,Rawlins EL
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to investigate human pluripotent stem cell differentiation to lung epithelium.
Fri Jun 30 00:00:00 UTC 2017
YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.
eLife
Lin C,Yao E,Zhang K,Jiang X,Croll S,Thompson-Peer K,Chuang PT
131900 was used in immunohistochemistry to test the role of YAP in branching morphogenesis for tissue patterning
Tue Mar 21 00:00:00 UTC 2017
Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice.
Nature medicine
Choi VM,Herrou J,Hecht AL,Teoh WP,Turner JR,Crosson S,Bubeck Wardenburg J
13-1900 was used in western blot to study the contribution to anaerobic sepsis in mice by activation of bacteroides fragilis toxin by a novel bacterial protease
Sun May 01 00:00:00 UTC 2016
An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.
Developmental cell
Balasooriya GI,Johnson JA,Basson MA,Rawlins EL
13-1900 was used in immunocytochemistry to determine how basal cell proliferation can be limited through an FGFR1-SPRY2 signaling axis in the steady-state airway epithelium
Mon Apr 04 00:00:00 UTC 2016
TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma.
Cell death and differentiation
Thakur AK,Nigri J,Lac S,Leca J,Bressy C,Berthezene P,Bartholin L,Chan P,Calvo E,Iovanna JL,Vasseur S,Guillaumond F,Tomasini R
13-1900 was used in immunohistochemistry - paraffin section and western blot to elucidate the favor of Smad-independent TGF-beta signaling that drives EMT in pancreatic ductal adenocarcinoma due to TAp73 loss
Mon Aug 01 00:00:00 UTC 2016
Tissue-specific roles for sonic hedgehog signaling in establishing thymus and parathyroid organ fate.
Development (Cambridge, England)
Bain VE,Gordon J,O'Neil JD,Ramos I,Richie ER,Manley NR
131900 was used in immunohistochemistry - paraffin section to alter sonic hedgehog signaling and assess the effects on patterning and organogenesis of the thymus and parathyroids
Tue Nov 01 00:00:00 UTC 2016
Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization.
The American journal of pathology
Ren S,Luo Y,Chen H,Warburton D,Lam HC,Wang LL,Chen P,Henske EP,Shi W
13-1900 was used in immunohistochemistry - paraffin section to study the role of Tsc2 in normal and pathological kidney and lung functions
Thu Dec 01 00:00:00 UTC 2016
All-trans retinoic acid promotes wound healing of primary amniocytes through the induction of LOXL4, a member of the lysyl oxidase family.
The international journal of biochemistry & cell biology
Rouzaire M,Comptour A,Belville C,Bouvier D,Clairefond G,Ponelle F,Sapin V,Gallot D,Blanchon L
131900 was used in immunocytochemistry to elucidate the molecular mechanisms by which all-trans retinoic acid promotes healing in fetal membranes
Thu Dec 01 00:00:00 UTC 2016
Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II.
Cell cycle (Georgetown, Tex.)
Priya R,Wee K,Budnar S,Gomez GA,Yap AS,Michael M
131900 was used in immunocytochemistry to investigate the role of Coronin 1B in regulating the non-muscle myosin II pool
Wed Nov 16 00:00:00 UTC 2016
Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts.
Developmental dynamics : an official publication of the American Association of Anatomists
Li N,Yousefi M,Nakauka-Ddamba A,Tobias JW,Jensen ST,Morrisey EE,Lengner CJ
13-1900 was used in flow cytometry and immunohistochemistry - paraffin section to investigate the heterogeneity in readouts in intestinal crypts in reference to canonical Wnt pathway activity
Mon Aug 01 00:00:00 UTC 2016
Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos.
Scientific reports
Lin J,Khan M,Zapiec B,Mombaerts P
131900 was used in immunocytochemistry to describe the derivation of 77 extraembryonic endoderm stem cell lines from 85 postimplantation embryos at embryonic day E5.5 or E6.5 and 41 extraembryonic endoderm stem cell lines from 69 preimplantation embryos at the blastocyst stage
Mon Dec 19 00:00:00 UTC 2016
Disparate Regulatory Mechanisms Control Fat3 and P75NTR Protein Transport through a Conserved Kif5-Interaction Domain.
PloS one
Cheng H,Burroughs-Garcia J,Birkness JE,Trinidad JC,Deans MR
131900 was used in immunocytochemistry to elucidate the regulation of Fat3 localization
Tue Jun 06 00:00:00 UTC 2017
Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.
PLoS genetics
Perdigoto CN,Dauber KL,Bar C,Tsai PC,Valdes VJ,Cohen I,Santoriello FJ,Zhao D,Zheng D,Hsu YC,Ezhkova E
13-1900 was used in immunohistochemistry - frozen section study the contribution of sonic hedgehog signaling to Merkel cell formation
Fri Jul 01 00:00:00 UTC 2016
Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling.
The Journal of cell biology
Cantú AV,Altshuler-Keylin S,Laird DJ
13-1900 was used in Flow Cytometry to suggest that the balance between expansion and movement of migratory PGCs is fine-tuned in different niches by the opposing β-catenin-dependent and Ror2-mediated pathways through Wnt5a.
Mon Jul 18 00:00:00 UTC 2016
Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions.
Nature cell biology
Priya R,Gomez GA,Budnar S,Verma S,Cox HL,Hamilton NA,Yap AS
13-1900 was used in immunocytochemistry and western blot to identify factors that regulate the stability of the RhoA zone
Thu Oct 01 00:00:00 UTC 2015
Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma.
Proceedings of the National Academy of Sciences of the United States of America
Guillaumond F,Bidaut G,Ouaissi M,Servais S,Gouirand V,Olivares O,Lac S,Borge L,Roques J,Gayet O,Pinault M,Guimaraes C,Nigri J,Loncle C,Lavaut MN,Garcia S,Tailleux A,Staels B,Calvo E,Tomasini R,Iovanna JL,Vasseur S
13-1900 was used in immunohistochemistry - frozen section to investigate metabolic pathways using pancreatic ductal adenocarcinoma cells
Tue Feb 24 00:00:00 UTC 2015
GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells.
The Journal of cell biology
Gao X,Bali AS,Randell SH,Hogan BL
13-1900 was used in immunohistochemistry to elucidate regeneration of a polarized mucociliary epithelium from basal stem cells by GRHL2
Mon Nov 09 00:00:00 UTC 2015
Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs.
The American journal of pathology
Eisses JF,Criscimanna A,Dionise ZR,Orabi AI,Javed TA,Sarwar S,Jin S,Zhou L,Singh S,Poddar M,Davis AW,Tosun AB,Ozolek JA,Lowe ME,Monga SP,Rohde GK,Esni F,Husain SZ
13-1900 was used in immunohistochemistry to report that valproic acid shifts the balance toward pancreatic injury and pancreatitis through histone deacetylase inhibition
Tue Dec 01 00:00:00 UTC 2015
Analysis of Wnt signalling dynamics during colon crypt development in 3D culture.
Scientific reports
Tan CW,Hirokawa Y,Burgess AW
13-1900 was used in immunohistochemistry to develop a method to grow physiologically-shaped, functional colon crypts in vitro.
Thu Jun 18 00:00:00 UTC 2015
VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation.
Cancer research
Fantozzi A,Gruber DC,Pisarsky L,Heck C,Kunita A,Yilmaz M,Meyer-Schaller N,Cornille K,Hopfer U,Bentires-Alj M,Christofori G
13-1900 was used in immunohistochemistry - paraffin section to evaluate the role of VEGF-mediated angiogenesis in EMT-induced cancer stemness and tumorigenesis
Sat Mar 01 00:00:00 UTC 2014
Colonic myofibroblast cell line stimulates colonoid formation.
American journal of physiology. Gastrointestinal and liver physiology
Hirokawa Y,Yip KH,Tan CW,Burgess AW
13-1900 was used in western blot to evaluate a coculture system for in vitro colonoid formation
Tue Apr 01 00:00:00 UTC 2014
Senescence-associated β-galactosidase activity marks the visceral endoderm of mouse embryos but is not indicative of senescence.
Genesis (New York, N.Y. : 2000)
Huang T,Rivera-Pérez JA
13-1900 was used in immunocytochemistry to study the beta-galactosidase activity in the visceral endoderm of mouse embryos
Tue Apr 01 00:00:00 UTC 2014
Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.
Genes to cells : devoted to molecular & cellular mechanisms
Yoshida T,Iwata T,Takai Y,Birchmeier W,Yamato M,Okano T
13-1900 was used in immunohistochemistry - paraffin section to investigate the role of afadin in epithelial tissue development using epithelium-specific afadin-deficient mice
Sat Nov 01 00:00:00 UTC 2014
Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens.
Cytoskeleton (Hoboken, N.J.)
Caldwell BJ,Lucas C,Kee AJ,Gaus K,Gunning PW,Hardeman EC,Yap AS,Gomez GA
13-1900 was used in immunocytochemistry to examine the role of tropomyosin isoforms in actomyosin biogenesis.
Mon Dec 01 00:00:00 UTC 2014
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.
Nature cell biology
Das A,Tanigawa S,Karner CM,Xin M,Lum L,Chen C,Olson EN,Perantoni AO,Carroll TJ
13-1900 was used in immunohistochemistry - paraffin section to investigate the role of Wnt9b in kidney progenitor cell renewal and differentiation.
Sun Sep 01 00:00:00 UTC 2013
MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells.
Nature structural & molecular biology
Judson RL,Greve TS,Parchem RJ,Blelloch R
13-1900 was used in immunocytochemistry to test if microRNAs target cooperating networks of genes.
Tue Oct 01 00:00:00 UTC 2013
The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β.
Genes & development
Correia AL,Mori H,Chen EI,Schmitt FC,Bissell MJ
13-1900 was used in immunocytochemistry and western blot to show that the hemopexin domain of MMP-3 simulates epithelial invasion and branching.
Mon Apr 01 00:00:00 UTC 2013
HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment.
Angiogenesis
Cedervall J,Zhang Y,Ringvall M,Thulin A,Moustakas A,Jahnen-Dechent W,Siegbahn A,Olsson AK
13-1900 was used in immunohistochemistry to investigate the effect of histidine-rich glycoprotein on tumor progression and its mechanism
Tue Oct 01 00:00:00 UTC 2013
CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions.
The Journal of cell biology
Shahbazi MN,Megias D,Epifano C,Akhmanova A,Gundersen GG,Fuchs E,Perez-Moreno M
13-1900 was used in immunocytochemistry and western blot to study the interaction between p120-catenin and CLASP2 that governs microtubule dynamics at adherens junctions
Mon Dec 23 00:00:00 UTC 2013
Murinization of internalin extends its receptor repertoire, altering Listeria monocytogenes cell tropism and host responses.
PLoS pathogens
Tsai YH,Disson O,Bierne H,Lecuit M
13-1900 was used in western blot to study listeriosis in wild-type mice using InlA that has been "murinized" to interact with mouse Ecad.
Mon Dec 09 00:00:00 UTC 2013
LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activation.
Molecular and cellular biology
Xu X,Jin D,Durgan J,Hall A
13-1900 was used in immunocytochemistry to report that LKB and p4RhoGEF control RhoA activity to promote apical junction assembly.
Mon Jul 01 00:00:00 UTC 2013
E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens.
Differentiation; research in biological diversity
Priya R,Yap AS,Gomez GA
13-1900 was used in immunocytochemistry to study how E-cadherin contributes to Rho signaling.
Tue Oct 01 00:00:00 UTC 2013
Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms.
Tissue engineering. Part C, Methods
Chavez MG,Yu W,Biehs B,Harada H,Snead ML,Lee JS,Desai TA,Klein OD
13-1900 was used in western blot to isolate and characterize dental epithelial stem cells.
Tue Jan 01 00:00:00 UTC 2013
Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation.
Nature cell biology
Stubbs JL,Vladar EK,Axelrod JD,Kintner C
13-1900 was used in immunohistochemistry to study initiation of multiciliate cell differentiation.
Sun Jan 08 00:00:00 UTC 2012
Mechanical compression drives cancer cells toward invasive phenotype.
Proceedings of the National Academy of Sciences of the United States of America
Tse JM,Cheng G,Tyrrell JA,Wilcox-Adelman SA,Boucher Y,Jain RK,Munn LL
Tue Jan 17 00:00:00 UTC 2012
Mind bomb 1 is required for pancreatic β-cell formation.
Proceedings of the National Academy of Sciences of the United States of America
Horn S,Kobberup S,Jørgensen MC,Kalisz M,Klein T,Kageyama R,Gegg M,Lickert H,Lindner J,Magnuson MA,Kong YY,Serup P,Ahnfelt-Rønne J,Jensen JN
Tue May 08 00:00:00 UTC 2012
Heparin-binding EGF-like growth factor promotes epithelial-mesenchymal transition in human keratinocytes.
The Journal of investigative dermatology
Stoll SW,Rittié L,Johnson JL,Elder JT
13-1900 was used in immunocytochemistry to investigate the role of HB-EGF in wound healing.
Sat Sep 01 00:00:00 UTC 2012
Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice.
Development (Cambridge, England)
Heaney JD,Anderson EL,Michelson MV,Zechel JL,Conrad PA,Page DC,Nadeau JH
13-1900 was used in immunohistochemistry (paraffin) to examine mouse strains with low versus high teratoma incidence.
Tue May 01 00:00:00 UTC 2012
Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice.
Biology of reproduction
Chawengsaksophak K,Svingen T,Ng ET,Epp T,Spiller CM,Clark C,Cooper H,Koopman P
13-1900 was used in immunohistochemistry to investigate the involvement of Wnt5a in sexual development.
Sun Jan 01 00:00:00 UTC 2012
TMED2/p24β1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines.
Placenta
Zakariyah A,Hou W,Slim R,Jerome-Majewska L
13-1900 was used in immunocytochemistry to study transmembrane emp24 domain in the human placenta.
Thu Mar 01 00:00:00 UTC 2012
Conditional ablation of the Notch2 receptor in the ocular lens.
Developmental biology
Saravanamuthu SS,Le TT,Gao CY,Cojocaru RI,Pandiyan P,Liu C,Zhang J,Zelenka PS,Brown NL
13-1900 was used in immunocytochemistry to study the Notch receptors needed for proper lens development.
Wed Feb 15 00:00:00 UTC 2012
Testis development requires the repression of Wnt4 by Fgf signaling.
Developmental biology
Jameson SA,Lin YT,Capel B
13-1900 was used in immunocytochemistry to study the role of Wnt repression in testicular development and the role played by Fgf signaling pathways.
Mon Oct 01 00:00:00 UTC 2012
BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm.
Developmental biology
Paca A,Séguin CA,Clements M,Ryczko M,Rossant J,Rodriguez TA,Kunath T
13-1900 was used in flow cytometry and immunohistochemistry - paraffin section to try to generate visceral endoderm.
Sun Jan 01 00:00:00 UTC 2012
Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development.
Developmental dynamics : an official publication of the American Association of Anatomists
Le TT,Conley KW,Mead TJ,Rowan S,Yutzey KE,Brown NL
13-1900 was used in immunohistochemistry - paraffin section to study Jag-Rbpj-mediated Notch signaling during early mouse lens development.
Thu Mar 01 00:00:00 UTC 2012
The effect of adriamycin exposure on the notochord of mouse embryos.
Birth defects research. Part B, Developmental and reproductive toxicology
Hajduk P,May A,Puri P,Murphy P
13-1900 was used in immunohistochemistry (frozen) to investigate the role of the notochord in foregut development.
Sun Apr 01 00:00:00 UTC 2012
The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells.
PloS one
Wei C,Bhattaram VK,Igwe JC,Fleming E,Tirnauer JS
13-1900 was used in immunocytochemistry to report that a germline LKB mutation in mice impairs spindle orientation in cells of the upper gastrointestinal tract and causes dramatic mislocalization of AMPK in mitotic cells.
Wed Jan 16 00:00:00 UTC 2013
Transcytosis of Listeria monocytogenes across the intestinal barrier upon specific targeting of goblet cell accessible E-cadherin.
The Journal of experimental medicine
Nikitas G,Deschamps C,Disson O,Niault T,Cossart P,Lecuit M
13-1900 was used in immunohistochemistry to investigate how Listeria monocytogenes crosses the epithelium.
Mon Oct 24 00:00:00 UTC 2011
T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.
The EMBO journal
Staal J,Driege Y,Bekaert T,Demeyer A,Muyllaert D,Van Damme P,Gevaert K,Beyaert R
13-1900 was used in western blot to investigate mucosa-associated lymphoid tissue 1 regulated signaling pathways.
Wed May 04 00:00:00 UTC 2011
Role of E-cadherin in the pathogenesis of gastroesophageal reflux disease.
The American journal of gastroenterology
Jovov B,Que J,Tobey NA,Djukic Z,Hogan BL,Orlando RC
13-1900 was used in immunohistochemistry to examine barrier function in the esophageal epithelium of patients with gastroesophageal reflux disease.
Wed Jun 01 00:00:00 UTC 2011
Salivary gland gene expression atlas identifies a new regulator of branching morphogenesis.
Journal of dental research
Musselmann K,Green JA,Sone K,Hsu JC,Bothwell IR,Johnson SA,Harunaga JS,Wei Z,Yamada KM
13-1900 was used in immunohistochemistry to search for novel regulators of branching morphogenesis.
Thu Sep 01 00:00:00 UTC 2011
E-cadherin expression in plasmacytoid, signet ring cell and micropapillary variants of urothelial carcinoma: comparison with usual-type high-grade urothelial carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Lim MG,Adsay NV,Grignon DJ,Osunkoya AO
13-1900 was used in immunohistochemistry to determine the expression of E-cadherin in variants of urothelial carcinoma
Tue Feb 01 00:00:00 UTC 2011
CD44 regulates tight-junction assembly and barrier function.
The Journal of investigative dermatology
Kirschner N,Haftek M,Niessen CM,Behne MJ,Furuse M,Moll I,Brandner JM
Fri Apr 01 00:00:00 UTC 2011
CD44 regulates tight-junction assembly and barrier function.
The Journal of investigative dermatology
Kirschner N,Haftek M,Niessen CM,Behne MJ,Furuse M,Moll I,Brandner JM
Fri Apr 01 00:00:00 UTC 2011
Rhou maintains the epithelial architecture and facilitates differentiation of the foregut endoderm.
Development (Cambridge, England)
Loebel DA,Studdert JB,Power M,Radziewic T,Jones V,Coultas L,Jackson Y,Rao RS,Steiner K,Fossat N,Robb L,Tam PP
13-1900 was used in immunohistochemistry - frozen section to study the role of Rhou in development.
Sat Oct 01 00:00:00 UTC 2011
Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis.
Development (Cambridge, England)
Grosse AS,Pressprich MF,Curley LB,Hamilton KL,Margolis B,Hildebrand JD,Gumucio DL
13-1900 was used in immunohistochemistry to investigate the cellular mechanisms for the growth and remodeling of early intestinal epithelium.
Sat Oct 01 00:00:00 UTC 2011
The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Collado MS,Thiede BR,Baker W,Askew C,Igbani LM,Corwin JT
13-1900 was used in immunocytochemistry to examine junctional cadherins in human and murine ears.
Wed Aug 17 00:00:00 UTC 2011
The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells.
Molecular and cellular biology
Wallace SW,Magalhaes A,Hall A
13-1900 was used in western blot to explore how Rho regulates epithelial apical junction formation
Sat Jan 01 00:00:00 UTC 2011
Decreased IGF type 1 receptor signaling in mammary epithelium during pregnancy leads to reduced proliferation, alveolar differentiation, and expression of insulin receptor substrate (IRS)-1 and IRS-2.
Endocrinology
Sun Z,Shushanov S,LeRoith D,Wood TL
13-1900 was used in immunohistochemistry (paraffin) to study the functions of IGF-1R during pregnancy and lactation.
Mon Aug 01 00:00:00 UTC 2011
Growth-limiting role of endothelial cells in endoderm development.
Developmental biology
Sand FW,Hörnblad A,Johansson JK,Lorén C,Edsbagge J,Ståhlberg A,Magenheim J,Ilovich O,Mishani E,Dor Y,Ahlgren U,Semb H
13-1900 was used in immunohistochemistry to elucidate the contribution of S1P(1)-signaling in endoderm development.
Fri Apr 15 00:00:00 UTC 2011
Diverse roles of Eph/ephrin signaling in the mouse lens.
PloS one
Cheng C,Gong X
Mon Apr 09 00:00:00 UTC 2012
Hakai reduces cell-substratum adhesion and increases epithelial cell invasion.
BMC cancer
Rodríguez-Rigueiro T,Valladares-Ayerbes M,Haz-Conde M,Aparicio LA,Figueroa A
13-1900 was used in immunocytochemistry to determine the role of Hakai in cell-substratum adhesions and invasion in epithelial cells.
Thu Nov 03 00:00:00 UTC 2011
Ror2 enhances polarity and directional migration of primordial germ cells.
PLoS genetics
Laird DJ,Altshuler-Keylin S,Kissner MD,Zhou X,Anderson KV
13-1900 was used in western blot to study primordial germ cell migration.
Thu Dec 01 00:00:00 UTC 2011
α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1.
Science signaling
Silvis MR,Kreger BT,Lien WH,Klezovitch O,Rudakova GM,Camargo FD,Lantz DM,Seykora JT,Vasioukhin V
13-1900 was used in immunohistochemistry to report that alphaE-catenin inhibits Yap1 to suppress squamous cell carcinoma.
Tue May 24 00:00:00 UTC 2011
Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis.
The Journal of biological chemistry
Durgan J,Kaji N,Jin D,Hall A
13-1900 was used in immunocytochemistry to investigate the role of Cdc42 in polarization of epithelial cells.
Fri Apr 08 00:00:00 UTC 2011
Differential expression of claudin tight junction proteins in the human cortical nephron.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Kirk A,Campbell S,Bass P,Mason J,Collins J
Thu Jul 01 00:00:00 UTC 2010
The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.
Investigative ophthalmology & visual science
Wiley LA,Dattilo LK,Kang KB,Giovannini M,Beebe DC
13-1900 was used in immunohistochemistry - paraffin section to determine the role of NF2 in fiber cell differentiation
Thu Jul 01 00:00:00 UTC 2010
Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B.
Molecular biology of the cell
Wallace SW,Durgan J,Jin D,Hall A
13-1900 was used in immunocytochemistry to investigate Cdc42 signaling that regulates apical junction formation
Wed Sep 01 00:00:00 UTC 2010
Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth.
Developmental dynamics : an official publication of the American Association of Anatomists
Yoshida T,Miyoshi J,Takai Y,Thesleff I
13-1900 was used in immunohistochemistry - paraffin section to characterize the teeth of nectin-1;nectin-3 compound mouse mutants.
Fri Oct 01 00:00:00 UTC 2010
Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling.
Blood
Banh C,Fugère C,Brossay L
13-1900 was used in flow cytometry to study the effect of KLRG1 and E-cadherin interactions in different immune cells
Thu Dec 17 00:00:00 UTC 2009
Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing.
The Journal of investigative dermatology
Singh P,Chen C,Pal-Ghosh S,Stepp MA,Sheppard D,Van De Water L
13-1900 was used in immunohistochemistry to characterize conditional integrin alpha9 knockout mice
Thu Jan 01 00:00:00 UTC 2009
E-Cadherin regulates neural stem cell self-renewal.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Karpowicz P,Willaime-Morawek S,Balenci L,DeVeale B,Inoue T,van der Kooy D
13-1900 was used in flow cytometry to study E-cadherin in neural stem cells
Wed Mar 25 00:00:00 UTC 2009
Enforced expression of Mixl1 during mouse ES cell differentiation suppresses hematopoietic mesoderm and promotes endoderm formation.
Stem cells (Dayton, Ohio)
Lim SM,Pereira L,Wong MS,Hirst CE,Van Vranken BE,Pick M,Trounson A,Elefanty AG,Stanley EG
13-1900 was used in flow cytometry and immunocytochemistry to ascertain the consequences of enforced Mixl1 expression during mouse embryonic stem cell differentiation
Sun Feb 01 00:00:00 UTC 2009
Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin).
The American journal of pathology
Manicone AM,Huizar I,McGuire JK
13-1900 was used in western blot to elucidate the function of CD103 in the lung
Tue Dec 01 00:00:00 UTC 2009
Functional suppression of E-cadherin by protein kinase Cdelta.
Journal of cell science
Chen CL,Chen HC
13-1900 was used in Immunocytochemistry to study the effect of green fluorescent protein-protein kinase C delta and GFP-PKCalpha on cell-cell junctions of Madin Darby canine kidney cells.
Sun Feb 15 00:00:00 UTC 2009
Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.
Molecular and cellular biology
Cattin AL,Le Beyec J,Barreau F,Saint-Just S,Houllier A,Gonzalez FJ,Robine S,Pinçon-Raymond M,Cardot P,Lacasa M,Ribeiro A
13-1900 was used in immunohistochemistry - paraffin section to examine the consequences of HNF-4alpha loss in the adult intestinal epithelium
Tue Dec 01 00:00:00 UTC 2009
Urine proteome analysis in murine nephrotoxic serum nephritis.
American journal of nephrology
Wenderfer SE,Dubinsky WP,Hernandez-Sanabria M,Braun MC
13-1900 was used in western blot to discuss proteomic analysis of urine for biomarker development
Fri Feb 05 00:00:00 UTC 2010
Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia.
Molecular biology of the cell
den Elzen N,Buttery CV,Maddugoda MP,Ren G,Yap AS
Sat Aug 01 00:00:00 UTC 2009
Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia.
Molecular biology of the cell
den Elzen N,Buttery CV,Maddugoda MP,Ren G,Yap AS
Sat Aug 01 00:00:00 UTC 2009
Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice.
Infection and immunity
Rhee KJ,Wu S,Wu X,Huso DL,Karim B,Franco AA,Rabizadeh S,Golub JE,Mathews LE,Shin J,Sartor RB,Golenbock D,Hamad AR,Gan CM,Housseau F,Sears CL
13-1900 was used in western blot to develop and characterize a murine model to study enterotoxigenic Bacteroides fragilis infection
Wed Apr 01 00:00:00 UTC 2009
BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.
Developmental biology
Cook MS,Coveney D,Batchvarov I,Nadeau JH,Capel B
13-1900 was used in immunohistochemistry to ascertain the mechanism underlying early loss of primordial germ cells
Wed Apr 15 00:00:00 UTC 2009
Jagged 1 is necessary for normal mouse lens formation.
Developmental biology
Le TT,Conley KW,Brown NL
13-1900 was used in immunohistochemistry - paraffin section to study the role of Jagged 1 in normal mouse lens formation
Wed Apr 01 00:00:00 UTC 2009
Abnormal placental development and early embryonic lethality in EpCAM-null mice.
PloS one
Nagao K,Zhu J,Heneghan MB,Hanson JC,Morasso MI,Tessarollo L,Mackem S,Udey MC
13-1900 was used in immunohistochemistry - frozen section to review data regarding EpCAM
Thu Dec 31 00:00:00 UTC 2009
T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model.
Cancer research
Hebbard LW,Garlatti M,Young LJ,Cardiff RD,Oshima RG,Ranscht B
13-1900 was used in immunohistochemistry - paraffin section to explore the function of T-cadherin in breast cancer
Sat Mar 01 00:00:00 UTC 2008
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis.
The Journal of cell biology
Jaffe AB,Kaji N,Durgan J,Hall A
13-1900 was used in immunocytochemistry to report that Cdc42 regulates epithelial tissue morphogenesis by controlling spindle orientation during cell division
Mon Nov 17 00:00:00 UTC 2008
Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.
Developmental biology
Marose TD,Merkel CE,McMahon AP,Carroll TJ
13-1900 was used in immunohistochemistry - frozen section to describe a role for beta-catenin in kidney development
Fri Feb 01 00:00:00 UTC 2008
Notch signaling regulates growth and differentiation in the mammalian lens.
Developmental biology
Rowan S,Conley KW,Le TT,Donner AL,Maas RL,Brown NL
13-1900 was used in immunohistochemistry - frozen section to investigate the role of Notch signaling in lens development
Mon Sep 01 00:00:00 UTC 2008
The cellular prion protein PrP(c) is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins.
PloS one
Morel E,Fouquet S,Strup-Perrot C,Pichol Thievend C,Petit C,Loew D,Faussat AM,Yvernault L,Pinçon-Raymond M,Chambaz J,Rousset M,Thenet S,Clair C
13-1900 was used in immunocytochemistry and western blot to discuss the expression of cellular prion protein by epithelial cells
Wed Aug 20 00:00:00 UTC 2008
Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.
Arthritis and rheumatism
Agarwal SK,Lee DM,Kiener HP,Brenner MB
13-1900 was used in western blot to examine cadherin expression in mouse fibroblast-like synoviocytes
Tue Apr 01 00:00:00 UTC 2008
The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny.
Development (Cambridge, England)
Kashiwagi M,Morgan BA,Georgopoulos K
13-1900 was used in immunohistochemistry to determine the role of Mi-2beta in skin development
Sun Apr 01 00:00:00 UTC 2007
P120 catenin is required for thickening of Schwann cell myelin.
Molecular and cellular neurosciences
Perrin-Tricaud C,Rutishauser U,Tricaud N
13-1900 was used in immunohistochemistry to study the role of P120 catenin in thickening of Schwann cell myelin
Tue May 01 00:00:00 UTC 2007
E-cadherin expression and bromodeoxyuridine incorporation during development of ovarian inclusion cysts in age-matched breeder and incessantly ovulated CD-1 mice.
Reproductive biology and endocrinology : RB&E
Fleming JS,McQuillan HJ,Millier MJ,Beaugié CR,Livingstone V
Wed Apr 11 00:00:00 UTC 2007
Self-organization and branching morphogenesis of primary salivary epithelial cells.
Tissue engineering
Wei C,Larsen M,Hoffman MP,Yamada KM
13-1900 was used in immunocytochemistry and immunohistochemistry to investigate the regeneration of submandibular gland epithelium
Sun Apr 01 00:00:00 UTC 2007
Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro.
The Journal of biological chemistry
Kaimori A,Potter J,Kaimori JY,Wang C,Mezey E,Koteish A
13-1900 was used in immunocytochemistry to demonstrate that TGF-beta1 induces an epithelial-to-mesenchymal transition in mature hepatocytes in vitro
Fri Jul 27 00:00:00 UTC 2007
Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin.
Oncogene
Janda E,Nevolo M,Lehmann K,Downward J,Beug H,Grieco M
13-1900 was used in immunocytochemistry and immunoprecipitation to elucidate the mechanisms by which Ras and TGFbeta pathways cooperate in epithelial-mesenchymal transition induction
Thu Nov 16 00:00:00 UTC 2006
Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production.
Development (Cambridge, England)
Ormestad M,Astorga J,Landgren H,Wang T,Johansson BR,Miura N,Carlsson P
13-1900 was used in immunohistochemistry to elucidate the roles of Foxf1 and Foxf2 in vertebrate gut development
Wed Mar 01 00:00:00 UTC 2006
Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1.
Journal of immunology (Baltimore, Md. : 1950)
Gründemann C,Bauer M,Schweier O,von Oppen N,Lässing U,Saudan P,Becker KF,Karp K,Hanke T,Bachmann MF,Pircher H
13-1900 was used in flow cytometry to identify E-cadherin as a ligand of killer cell lectin-like receptor G1
Wed Feb 01 00:00:00 UTC 2006
Cell and fibronectin dynamics during branching morphogenesis.
Journal of cell science
Larsen M,Wei C,Yamada KM
13-1900 was used in immunocytochemistry to identify a new mechanism for branching morphogenesis involving fibronectin
Tue Aug 15 00:00:00 UTC 2006
CD8+ T regulatory cells use a novel genetic program that includes CD103 to suppress Th1 immunity in eye-derived tolerance.
Investigative ophthalmology & visual science
Keino H,Masli S,Sasaki S,Streilein JW,Stein-Streilein J
13-1900 was used in flow cytometry to identify the genes and molecules critical for CD8+ T regulatory cell functions in anterior chamber-associated immune deviation
Sat Apr 01 00:00:00 UTC 2006
The expression profiles of nuclear receptors in the developing and adult kidney.
Molecular endocrinology (Baltimore, Md.)
Suh JM,Yu CT,Tang K,Tanaka T,Kodama T,Tsai MJ,Tsai SY
13-1900 was used in immunohistochemistry to investigate the roles of nuclear receptors in kidney development
Fri Dec 01 00:00:00 UTC 2006
E-cadherin-dependent transcriptional control of apolipoprotein A-IV gene expression in intestinal epithelial cells: a role for the hepatic nuclear factor 4.
The Journal of biological chemistry
Peignon G,Thenet S,Schreider C,Fouquet S,Ribeiro A,Dussaulx E,Chambaz J,Cardot P,Pinçon-Raymond M,Le Beyec J
Fri Feb 10 00:00:00 UTC 2006
In vitro derivation and expansion of endothelial cells from embryonic stem cells.
Methods in molecular biology (Clifton, N.J.)
McCloskey KE,Stice SL,Nerem RM
13-1900 was used in immunocytochemistry to describe methods to generate highly purified populations of actively proliferating endothelial cells from mouse embryonic stem cells
Tue Aug 22 00:00:00 UTC 2006
Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney.
Kidney international
Naim E,Bernstein A,Bertram JF,Caruana G
13-1900 was used in immunohistochemistry - paraffin section to study the role of discs large 1 during development of the mouse kidney
Thu Sep 01 00:00:00 UTC 2005
Intercellular junctions in Ewing sarcoma/primitive neuroectodermal tumor: additional evidence of epithelial differentiation.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Schuetz AN,Rubin BP,Goldblum JR,Shehata B,Weiss SW,Liu W,Wick MR,Folpe AL
13-1900 was used in immunohistochemistry - paraffin section to assess intercellular junction protein expression in Ewing sarcoma/primitive neuroectodermal tumors
Tue Nov 01 00:00:00 UTC 2005
The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells.
Development (Cambridge, England)
Ng ES,Azzola L,Sourris K,Robb L,Stanley EG,Elefanty AG
13-1900 was used in flow cytometry and western blot to study the role of Mixl1 in development of hematopoietic mesoderm
Tue Mar 01 00:00:00 UTC 2005
Adherens junctions in myelinating Schwann cells stabilize Schmidt-Lanterman incisures via recruitment of p120 catenin to E-cadherin.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tricaud N,Perrin-Tricaud C,Brusés JL,Rutishauser U
Wed Mar 30 00:00:00 UTC 2005
Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3.
Developmental biology
Rivera-Pérez JA,Magnuson T
13-1900 was used in immunohistochemistry - frozen section to examine the proposed correlation between the expression of Brachyury and Wnt3 in the epiblast
Thu Dec 15 00:00:00 UTC 2005
Beta-catenin is essential for pancreatic acinar but not islet development.
Development (Cambridge, England)
Murtaugh LC,Law AC,Dor Y,Melton DA
13-1900 was used in Immunohistochemistry to show here that the early pancreatic epithelium exhibits a specific enrichment in unphosphorylated beta-catenin protein, a hallmark of activation of the canonical Wnt signaling pathway.
Tue Nov 01 00:00:00 UTC 2005
Autocrine IL-10 partially prevents differentiation of neonatal dendritic epidermal leukocytes into Langerhans cells.
Journal of leukocyte biology
Chang-Rodriguez S,Ecker R,Stingl G,Elbe-Bürger A
13-1900 was used in immunohistochemistry to test if reduced immune responsiveness in early life contributes to the immaturity of neonatal antigen-presenting cells
Wed Sep 01 00:00:00 UTC 2004
Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor.
The American journal of pathology
Shen X,Kramer RH
13-1900 was used in flow cytometry and immunocytochemistry to investigate factors that protect malignant cells from detachment-induced death
Fri Oct 01 00:00:00 UTC 2004
Early loss of E-cadherin from cell-cell contacts is involved in the onset of Anoikis in enterocytes.
The Journal of biological chemistry
Fouquet S,Lugo-Martínez VH,Faussat AM,Renaud F,Cardot P,Chambaz J,Pinçon-Raymond M,Thenet S
13-1900 was used in immunohistochemistry and western blot to determine the role of E-cadherin in the control of anoikis of normal intestinal epithelial cells
Fri Oct 08 00:00:00 UTC 2004
Regional distribution of alpha9beta1 integrin within the limbus of the mouse ocular surface.
Developmental dynamics : an official publication of the American Association of Anatomists
Pajoohesh-Ganji A,Ghosh SP,Stepp MA
13-1900 was used in Immunohistochemistry to show that alpha9 integrin is present on the adult mouse cornea in the limbal basal cells and is more abundant in the apical-most cytoplasm of the limbal basal cells, where it can be found colocalized within the plasma membrane with E-cadherin.
Thu Jul 01 00:00:00 UTC 2004
Angiogenic acceleration of Neu induced mammary tumor progression and metastasis.
Cancer research
Oshima RG,Lesperance J,Munoz V,Hebbard L,Ranscht B,Sharan N,Muller WJ,Hauser CA,Cardiff RD
13-1900 was used in Immunohistochemistry (Frozen), Western Blot to demonstrate the angiogenic restriction of early hyperplastic mammary lesions.
Thu Jan 01 00:00:00 UTC 2004
NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.
Genes & development
Lallemand D,Curto M,Saotome I,Giovannini M,McClatchey AI
13-1900 was used in immunocytochemistry and immunoprecipitation to demonstrate that Nf2 deficiency in primary cells results in the inability to undergo contact-dependent growth arrest and form stable cadherin-containing cell:cell junctions.
Thu May 01 00:00:00 UTC 2003
Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice.
The Journal of physiology
Gouyon F,Caillaud L,Carriere V,Klein C,Dalet V,Citadelle D,Kellett GL,Thorens B,Leturque A,Brot-Laroche E
Sat Nov 01 00:00:00 UTC 2003
Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice.
The Journal of physiology
Gouyon F,Caillaud L,Carriere V,Klein C,Dalet V,Citadelle D,Kellett GL,Thorens B,Leturque A,Brot-Laroche E
Sat Nov 01 00:00:00 UTC 2003
Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium.
The American journal of pathology
McGuire JK,Li Q,Parks WC
13-1900 was used in immunohistochemistry and western blot to elucidate the mechanism of matrilysin in repair.
Sun Jun 01 00:00:00 UTC 2003
Requirement for Pax6 in corneal morphogenesis: a role in adhesion.
Journal of cell science
Davis J,Duncan MK,Robison WG,Piatigorsky J
13-1900 was used in western blot to demonstrate that Pax6 is necessary for normal corneal morphogenesis.
Sun Jun 01 00:00:00 UTC 2003
Purified and proliferating endothelial cells derived and expanded in vitro from embryonic stem cells.
Endothelium : journal of endothelial cell research
McCloskey KE,Lyons I,Rao RR,Stice SL,Nerem RM
13-1900 was used in flow cytometry to describe methods to obtain proliferating populations of homogeneous endothelial cells from mouse embryonic stem cells
Mon Jul 12 00:00:00 UTC 2004
Dynamic morphogenetic events characterize the mouse visceral endoderm.
Developmental biology
Rivera-Pérez JA,Mager J,Magnuson T
13-1900 was used in Immunohistochemistry-immunofluorescence to show that Hex-expressing cells have a tall, columnar epithelial morphology, which distinguishes them from other visceral endoderm cells.
Mon Sep 15 00:00:00 UTC 2003
Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis.
Cancer cell
Lopez T,Hanahan D
13-1900 was used in immunohistochemistry (frozen) to investigate the role of IGF-1R on islet tumorigenesis.
Wed May 01 00:00:00 UTC 2002
Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation.
Cancer research
Tong WM,Cortes U,Hande MP,Ohgaki H,Cavalli LR,Lansdorp PM,Haddad BR,Wang ZQ
13-1900 was used in immunohistochemistry (paraffin) to suggest that defects in DNA end-processing molecules contribute to formation of hepatocellular carcinoma.
Sun Dec 01 00:00:00 UTC 2002
E-Cadherin and tight junctions between epithelial cells of different animal species.
Pflugers Archiv : European journal of physiology
Contreras RG,Shoshani L,Flores-Maldonado C,Lázaro A,Monroy AO,Roldán ML,Fiorentino R,Cereijido M
13-1900 was used in immunocytochemistry and western blot to investigate tight junctions and E-cadherin in heterotypic borders.
Mon Jul 01 00:00:00 UTC 2002
Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Wali RK,Khare S,Tretiakova M,Cohen G,Nguyen L,Hart J,Wang J,Wen M,Ramaswamy A,Joseph L,Sitrin M,Brasitus T,Bissonnette M
Sun Dec 01 00:00:00 UTC 2002
Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Wali RK,Khare S,Tretiakova M,Cohen G,Nguyen L,Hart J,Wang J,Wen M,Ramaswamy A,Joseph L,Sitrin M,Brasitus T,Bissonnette M
Sun Dec 01 00:00:00 UTC 2002
Progressive changes in adherens junction structure during intestinal adenoma formation in Apc mutant mice.
The Journal of biological chemistry
Carothers AM,Melstrom KA,Mueller JD,Weyant MJ,Bertagnolli MM
13-1900 was used in immunohistochemistry (paraffin) and western blot to examine the effect of the Apc(Min) mutation upon cell-cell adhesion.
Fri Oct 19 00:00:00 UTC 2001
An ovarian adenocarcinoma line derived from SV40/E-cadherin-transfected normal human ovarian surface epithelium.
International journal of cancer
Ong A,Maines-Bandiera SL,Roskelley CD,Auersperg N
13-1900 was used in immunocytochemistry to report that ovarian adenocarcinomas can be derived by genetic manipulation of normal human ovarian surface epithelium.
Tue Feb 01 00:00:00 UTC 2000
Up-regulation of VCAM-1 and differential expansion of beta integrin-expressing T lymphocytes are associated with immunity to pulmonary Mycobacterium tuberculosis infection.
Journal of immunology (Baltimore, Md. : 1950)
Feng CG,Britton WJ,Palendira U,Groat NL,Briscoe H,Bean AG
13-1900 was used in immunohistochemistry (frozen) to determine the expression of endothelial addressins and integrins on T cells during infection with Mycobacterium tuberculosis.
Mon May 01 00:00:00 UTC 2000
Mouse primordial germ cells lacking beta1 integrins enter the germline but fail to migrate normally to the gonads.
Development (Cambridge, England)
Anderson R,Fässler R,Georges-Labouesse E,Hynes RO,Bader BL,Kreidberg JA,Schaible K,Heasman J,Wylie C
13-1900 was used in flow cytometry to test if integrins mediate primordial germ cell migration.
Thu Apr 01 00:00:00 UTC 1999
Loss of function of the homeobox gene Hoxa-9 perturbs early T-cell development and induces apoptosis in primitive thymocytes.
Blood
Izon DJ,Rozenfeld S,Fong ST,Kömüves L,Largman C,Lawrence HJ
13-1900 was used in flow cytometry to explore the role for Hox genes in T-cell development.
Wed Jul 15 00:00:00 UTC 1998
Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement.
Journal of cell science
Danjo Y,Gipson IK
13-1900 was used in immunohistochemistry to elucidate the role of the actin filament cable in wound healing.
Sun Nov 01 00:00:00 UTC 1998
The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts.
The Journal of cell biology
Braga VM,Machesky LM,Hall A,Hotchin NA
Mon Jun 16 00:00:00 UTC 1997
E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model.
Cancer research
Mbalaviele G,Dunstan CR,Sasaki A,Williams PJ,Mundy GR,Yoneda T
13-1900 was used in western blot to examine the involvement of E-cadherin in breast cancer metastasis to bone.
Sun Sep 01 00:00:00 UTC 1996
A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.
Molecular biology of the cell
Wesseling J,van der Valk SW,Hilkens J
13-1900 was used in immunocytochemistry to report that the length of episialin determines the inhibition of E-cadherin-mediated cell-cell interactions.
Mon Apr 01 00:00:00 UTC 1996
Novel E-cadherin-mediated adhesion in peripheral nerve: Schwann cell architecture is stabilized by autotypic adherens junctions.
The Journal of cell biology
Fannon AM,Sherman DL,Ilyina-Gragerova G,Brophy PJ,Friedrich VL,Colman DR
13-1900 was used in immunoprecipitation and western blot to report that E-cadherin is a major adhesive glycoprotein in peripheral nervous system Schwann cells.
Sat Apr 01 00:00:00 UTC 1995
Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes.
The Journal of cell biology
Shibamoto S,Hayakawa M,Takeuchi K,Hori T,Miyazawa K,Kitamura N,Johnson KR,Wheelock MJ,Matsuyoshi N,Takeichi M
Wed Mar 01 00:00:00 UTC 1995
Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line.
The Journal of cell biology
Watabe M,Nagafuchi A,Tsukita S,Takeichi M
Sat Oct 01 00:00:00 UTC 1994
Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization.
Cell
Hirano S,Kimoto N,Shimoyama Y,Hirohashi S,Takeichi M
Fri Jul 24 00:00:00 UTC 1992
Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization.
Cell
Hirano S,Kimoto N,Shimoyama Y,Hirohashi S,Takeichi M
Fri Jul 24 00:00:00 UTC 1992
Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization.
Cell
Hirano S,Kimoto N,Shimoyama Y,Hirohashi S,Takeichi M
Fri Jul 24 00:00:00 UTC 1992
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis.
Development (Cambridge, England)
Takeichi M
Fri Apr 01 00:00:00 UTC 1988
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis.
Development (Cambridge, England)
Takeichi M
Fri Apr 01 00:00:00 UTC 1988
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis.
Development (Cambridge, England)
Takeichi M
Fri Apr 01 00:00:00 UTC 1988
