Proteintech

E2F7 Polyclonal Antibody

E2F7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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E2F7 Antibody (24489-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 24489-1-AP ( E2F7 Antibody) at dilution of 1:50 (under 40x lens).

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Product Details

24489-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 11 publications 11 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E2F7 Fusion Protein Ag21599 (369-713 aa encoded by BC136366)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.38 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VDFSSSDEE LVDVSASVLP ELKRETYGQI QVCAKQKLAR HGSFNTVQAS ERIQRKVNSE PSSPYREEQG SGGYSLEIGS LAAVYRQKIE DNSQGKAFAS KRVVPPSSSL DPVAPFPVLS VDPEYCVNPL AHPVFSVAQT DLQAFSMQNG LNGQVDVSLA SAASAVESLK PALLAGQPLV YVPSASLFML YGSLQEGPAS GSGSERDDRS SEAPATVELS SAPSAQKRLC EERKPQEEDE PATKRQSREY EDGPLSLVMP KKPSDSTDLA SPKTMGNRAS IPLKDIHVNG QLPAAEEISG KATANSLVSS EWGNPSRNTD VEKPSKENES TKEPSLLQYL CVQSPA (369-713 aa encoded by BC136366)

Target Information

E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Dexmedetomidine promotes ferroptotic cell death in gastric cancer via hsa_circ_0008035/miR-302a/E2F7 axis.

The Kaohsiung journal of medical sciences

Gao X,Wang XL

Sat Apr 01 00:00:00 UTC 2023

A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma.

Acta biomaterialia

Ma Y,Lin H,Wang P,Yang H,Yu J,Tian H,Li T,Ge S,Wang Y,Jia R,Leong KW,Ruan J

Sun Jan 01 00:00:00 UTC 2023

A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma.

Acta biomaterialia

Ma Y,Lin H,Wang P,Yang H,Yu J,Tian H,Li T,Ge S,Wang Y,Jia R,Leong KW,Ruan J

Sun Jan 01 00:00:00 UTC 2023

A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma.

Acta biomaterialia

Ma Y,Lin H,Wang P,Yang H,Yu J,Tian H,Li T,Ge S,Wang Y,Jia R,Leong KW,Ruan J

Sun Jan 01 00:00:00 UTC 2023

A miRNA-based gene therapy nanodrug synergistically enhances pro-inflammatory antitumor immunity against melanoma.

Acta biomaterialia

Ma Y,Lin H,Wang P,Yang H,Yu J,Tian H,Li T,Ge S,Wang Y,Jia R,Leong KW,Ruan J

Sun Jan 01 00:00:00 UTC 2023

Comprehensive analysis to identify the RP11-478C19.2/ E2F7 axis as a novel biomarker for treatment decisions in clear cell renal cell carcinoma.

Translational oncology

Zeng K,Song G,Chen B,Gao X,Liu C,Miao J,Ruan Y,Luan Y,Chen X,Liu J,Li Q,Liu B

Tue Nov 01 00:00:00 UTC 2022

APEX2-Mediated Proximity Labeling Resolves the DDIT4-Interacting Proteome.

International journal of molecular sciences

Naki M,Gourdomichali O,Zonke K,Kattan FG,Makridakis M,Kontostathi G,Vlahou A,Doxakis E

Fri May 06 00:00:00 UTC 2022

HOTAIRM1 Maintained the Malignant Phenotype of tMSCs Transformed by GSCs via E2F7 by Binding to FUS.

Journal of oncology

Liu L,Zhou Y,Dong X,Li S,Cheng S,Li H,Li Y,Yuan J,Wang L,Dong J

Sat Jul 16 00:00:00 UTC 2022

Comprehensive Analysis of the E2F Transcription Factor Family in Human Lung Adenocarcinoma.

International journal of general medicine

Wang Q,Liu J,Cheang I,Li J,Chen T,Li Y,Yu B

Sat Jul 16 00:00:00 UTC 2022

LINC00174 Facilitates Proliferation and Migration of Colorectal Cancer Cells via MiR-3127-5p/ E2F7 Axis.

Journal of microbiology and biotechnology

Ma Y,Li Y,Tang Y,Tang N,Wang D,Li X

Sat Aug 28 00:00:00 UTC 2021

Long noncoding RNA LINC00284 facilitates cell proliferation in papillary thyroid cancer via impairing miR-3127-5p targeted E2F7 suppression.

Cell death discovery

Zhou B,Ge Y,Shao Q,Yang L,Chen X,Jiang G

Sat Jun 26 00:00:00 UTC 2021

E2F1/2/7/8 as independent indicators of survival in patients with cervical squamous cell carcinoma.

Cancer cell international

Yang C,Zhang ZC,Liu TB,Xu Y,Xia BR,Lou G

Sun Apr 17 00:00:00 UTC 2022

E2F1/2/7/8 as independent indicators of survival in patients with cervical squamous cell carcinoma.

Cancer cell international

Yang C,Zhang ZC,Liu TB,Xu Y,Xia BR,Lou G

Sun Apr 17 00:00:00 UTC 2022

E2F1/2/7/8 as independent indicators of survival in patients with cervical squamous cell carcinoma.

Cancer cell international

Yang C,Zhang ZC,Liu TB,Xu Y,Xia BR,Lou G

Sun Apr 17 00:00:00 UTC 2022

Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas.

Endocrine pathology

Gucer H,Caliskan S,Kefeli M,Mete O

Sun Mar 01 00:00:00 UTC 2020

Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma.

BioMed research international

Pan Z,Li L,Fang Q,Qian Y,Zhang Y,Zhu J,Ge M,Huang P

Thu Dec 12 00:00:00 UTC 2019

HOXD-AS1/miR-130a sponge regulates glioma development by targeting E2F8.

International journal of cancer

Chen Y,Zhao F,Cui D,Jiang R,Chen J,Huang Q,Shi J

Fri Jun 01 00:00:00 UTC 2018

HOXD-AS1/miR-130a sponge regulates glioma development by targeting E2F8.

International journal of cancer

Chen Y,Zhao F,Cui D,Jiang R,Chen J,Huang Q,Shi J

Fri Jun 01 00:00:00 UTC 2018

Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis.

Cell death & disease

Coutts AS,Munro S,La Thangue NB

Tue May 01 00:00:00 UTC 2018

Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis.

Cell death & disease

Coutts AS,Munro S,La Thangue NB

Tue May 01 00:00:00 UTC 2018

The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.

Oncotarget

Fan L,Cao X,Yan H,Wang Q,Tian X,Zhang L,He X,Borjihan G

Tue Jul 18 00:00:00 UTC 2017

The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.

Oncotarget

Fan L,Cao X,Yan H,Wang Q,Tian X,Zhang L,He X,Borjihan G

Tue Jul 18 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: E2F-7; FLJ12981; no; Transcription factor E2F7

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Gene Aliases: E2F7

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UniProt ID: (Human) Q96AV8

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Entrez Gene ID: (Human) 144455

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Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding core promoter binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding identical protein binding

Process(es)

negative regulation of transcription from RNA polymerase II promoter placenta development sprouting angiogenesis transcription, DNA-templated DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest negative regulation of cell proliferation DNA damage response, signal transduction by p53 class mediator negative regulation of cytokinesis positive regulation of DNA endoreduplication positive regulation of transcription from RNA polymerase II promoter trophoblast giant cell differentiation chorionic trophoblast cell differentiation hepatocyte differentiation negative regulation of transcription involved in G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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E2F7 Polyclonal Antibody

E2F7 Antibody (24489-1-AP) in IHC (P)

Product Details

24489-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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