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Proteintech
E2F8 Polyclonal Antibody
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Product Details
13425-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E2F8 Fusion Protein Ag4216 (78-508 aa encoded by BC028244)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAQLAAICK MQLEEQSSES RQKVKVQLAR SGPCKPVAPL DPPVNAEMEL TAPSLIQPLG MVPLIPSPLS SAVPLILPQA PSGPSYAIYL QPTQAHQSVT PPQGLSPTVC TTHSSKATGS KDSTDATTEK AANDTSKASA STRPGSLLPA PERQGAKSRT REPAGERGSK RASMLEDSGS KKKFKEDLKG LENVSATLFP SGYLIPLTQC SSLGAESILS GKENSSALSP NHRIYSSPIA GVIPVTSSEL TAVNFPSFHV TPLKLMVSPT SVAAVPVGNS PALASSHPVP IQNPSSAIVN FTLQHLGLIS PNVQLSASPG SGIVPVSPRI ESVNVAPENA GTQQGRATNY DSPVPGQSQP NGQSVAVTGA QQPVPVTPKG SQLVAESFFR TPGGPTKPTS SSCMDFEGAN KTSLGTLFVP QRKLEVSTED VH (78-508 aa encoded by BC028244)
Target Information
E2F transcription factors, such as E2F8, are essential for orchestrating expression of genes required for cell cycle progression and proliferation (Christensen et al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E2F 8; E2F family member 8; E2F-8; FLJ23311; Transcription factor E2F8
Gene Aliases: E2F-8; E2F8
UniProt ID: (Human) A0AVK6
Entrez Gene ID: (Human) 79733
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
protein homodimerization activity
negative regulation of transcription from RNA polymerase II promoter
placenta development
sprouting angiogenesis
transcription, DNA-templated
cell proliferation
negative regulation of cytokinesis
positive regulation of DNA endoreduplication
cell cycle comprising mitosis without cytokinesis
positive regulation of transcription from RNA polymerase II promoter
trophoblast giant cell differentiation
chorionic trophoblast cell differentiation
hepatocyte differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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