Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Alomone Labs, LTD
EAAT1 (GLAST) (extracellular) Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 4
EAAT1 (GLAST) (extracellular) Antibody (AGC-021-200UL) in ICC/IF
Expression of EAAT1 in human U-87 MG cells - Cell surface detection of EAAT1 in live intact human U-87 MG glioblastoma cells. A. Extracellular staining of cells using Anti-EAAT1 (GLAST) (extracellular) Antibody (#AGC-021), (1:100) followed by goat Anti-rabbit-Alexa-Fluor-594 secondary Antibody (red). B. Live image of the cells. C. Merge of A and B.
Product Details
AGC-021-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KQFKTSYEKRSFK, corresponding to amino acids 188-200 of rat EAAT1, 2nd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: EAAT-1; Excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST-1; Glial glutamate transporter; Glial high affinity glutamate transporter; GluT-1; glutamate transporter; glutamate/aspartate transporter; High-affinity neuronal glutamate transporter; Sodium-dependent glutamate/aspartate transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3; Solute carrier family 1 member 3; solute carrier family 1, member 3
Gene Aliases: AI504299; B430115D02Rik; EA6; EAAT1; GLAST; GLAST-1; GLAST1; GLU-T; GluT-1; Gmt1; MGluT1; SLC1A3
UniProt ID: (Human) P43003, (Rat) P24942, (Mouse) P56564
Entrez Gene ID: (Human) 6507, (Rat) 29483, (Mouse) 20512
neurotransmitter uptake
positive regulation of defense response to virus by host
amino acid transmembrane transport
glutamate biosynthetic process
ion transport
chemical synaptic transmission
sensory perception of sound
response to light stimulus
gamma-aminobutyric acid biosynthetic process
response to wounding
glutamate secretion
cranial nerve development
auditory behavior
response to drug
malate-aspartate shuttle
response to antibiotic
cell morphogenesis involved in neuron differentiation
positive regulation of synaptic transmission
neuromuscular process controlling balance
L-glutamate import
D-aspartate import
L-glutamate transmembrane transport
mitophagy in response to mitochondrial depolarization
xenophagy
glutamate metabolic process
neurotransmitter transport
response to inorganic substance
L-glutamate transport
sodium ion transmembrane transport
transport
dicarboxylic acid transport
response to amino acid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support