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          • Primary Antibodies ›
          • EDC3 Antibodies

          Proteintech

          EDC3 Polyclonal Antibody

          1 Reference
          View all (13) EDC3 antibodies

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          Datasheet
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          Datasheet
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          Cite EDC3 Polyclonal Antibody

          • Antibody Testing Data (17)
          EDC3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          EDC3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 17

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          EDC3 Antibody (16486-1-AP) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using EDC3 antibody (Product # 16486-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          EDC3 Antibody in Immunocytochemistry (ICC/IF)
          EDC3 Antibody in Immunocytochemistry (ICC/IF)
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EDC3 Antibody in Western Blot (WB)
          EDC3 Antibody in Western Blot (WB)
          EDC3 Antibody in Immunoprecipitation (IP)

          Product Details

          16486-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:6,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          EDC3 Fusion Protein Ag9608 (158-508 aa encoded by BC021271)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.23 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: RHNSWSSSS RHPNQATPKK SGLKNGQMKN KDDECFGDDI EEIPDTDFDF EGNLALFDKA AVFEEIDTYE RRSGTRSRGI PNERPTRYRH DENILESEPI VYRRIIVPHN VSKEFCTDSG LVVPSISYEL HKKLLSVAEK HGLTLERRLE MTGVCASQMA LTLLGGPNRL NPKNVHQRPT VALLCGPHVK GAQGISCGRH LANHDVQVIL FLPNFVKMLE SITNELSLFS KTQGQQVSSL KDLPTSPVDL VINCLDCPEN VFLRDQPWYK AAVAWANQNR APVLSIDPPV HEVEQGIDAK WSLALGLPLP LGEHAGRIYL CDIGIPQQVF QEVGINYHSP FGCKFVIPLH SA (158-508 aa encoded by BC021271)

          Target Information

          This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: enhancer of mRNA decapping 3; enhancer of mRNA decapping 3 homolog; Enhancer of mRNA-decapping protein 3; hYjeF_N2; hYjeF_N2-15q23; LSM16 homolog; LSM16 homolog (EDC3, S. cerevisiae); yjeF domain containing; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; YjeF_N2

          View more View less

          Gene Aliases: AA517853; EDC3; LSM16; MRT50; PP844; RGD1306898; YJDC; YJEFN2

          View more View less

          UniProt ID: (Human) Q96F86, (Mouse) Q8K2D3

          View more View less

          Entrez Gene ID: (Human) 80153, (Rat) 315708, (Mouse) 353190

          View more View less

          Function(s)
          mRNA binding protein binding identical protein binding phosphodiesterase decapping endonuclease activity RNA binding
          Process(es)
          deadenylation-independent decapping of nuclear-transcribed mRNA cytoplasmic mRNA processing body assembly exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay RNA phosphodiester bond hydrolysis, endonucleolytic biological_process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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