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Invitrogen
EDDM3B Polyclonal Antibody
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Product Details
PA5-51559
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EDDM3B. Recombinant protein control fragment (Product #RP-88881).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640887
Product Specific Information
Immunogen sequence: EVSWREFMKQ HYLSPSREFR EYKCDVLMRE NEALKDKSSH MFIYISWYKI EHICTSDNWM DRFRNAYVWV QNPLKVLKCH QENSKNSYTE SRSFNYIEFH CSMDGYVDSI EDLKMVEPIG N
Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 58%.
Target Information
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymal secretory protein E3 beta; Epididymal secretory protein E3-beta; family with sequence similarity 12, member B (epididymal); HE3-beta; human epididymis-specific 3 beta; Human epididymis-specific protein 3-beta; ribonuclease A M2
Gene Aliases: EDDM3B; EP3B; FAM12B; HE3-BETA; HE3B; RAM2; UNQ6412/PRO21187
UniProt ID: (Human) P56851
Entrez Gene ID: (Human) 64184
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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