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Invitrogen
EDEM3 Polyclonal Antibody
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Product Details
PA5-55253
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EDEM3. Recombinant protein control fragment (Product #RP-94076).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2640891
Product Specific Information
Immunogen sequence: FRSGAKPPLR ARDFMATNPE HLEILKKMGV SLIHLKDGRV QLVQHAIQAA SSIDAEDGLR FMQEMIELSS QQQKEQQLPP RAVQIVSHPF FGRVVLTAGP
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-1,2-mannosidase EDEM3; ER degradation enhancer, mannosidase alpha-like 3; ER degradation-enhancing -mannosidase-like protein 3; ER degradation-enhancing alpha-mannosidase-like 3; ER degradation-enhancing alpha-mannosidase-like protein 3
Gene Aliases: C1orf22; EDEM3
UniProt ID: (Human) Q9BZQ6
Entrez Gene ID: (Human) 80267
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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