Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
EDG2 Recombinant Rabbit Monoclonal Antibody (4C3)
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
EDG2 Antibody (MA5-38395) in WB
Western Blot analysis of EDG2 using EDG2 Monoclonal Antibody (Product # MA5-38395) at 1:1,000. Positive WB detected in: Hela whole cell lysate, A375 whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 42, 42 kDa. Observed band size: 42 kDa
Product Details
MA5-38395
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4C3
Immunogen
A synthesized peptide derived from human EDG2
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 150mM NaCl
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2898309
Product Specific Information
This antibody has been tested in direct-ELISA
Target Information
EDG2 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; LPA receptor 1; LPA-1; Lysophosphatidic acid receptor 1; Lysophosphatidic acid receptor Edg-2; ventricular zone gene 1
Gene Aliases: edg-2; EDG2; Gpcr26; GPR26; LPA1; LPAR1; Mrec1.3; rec.1.3; vzg-1; VZG1
UniProt ID: (Human) Q92633
Entrez Gene ID: (Human) 1902
activation of MAPK activity
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
activation of phospholipase C activity
positive regulation of cytosolic calcium ion concentration
regulation of cell shape
negative regulation of neuron projection development
oligodendrocyte development
cerebellum development
optic nerve development
corpus callosum development
negative regulation of cAMP biosynthetic process
bleb assembly
positive regulation of Rho protein signal transduction
myelination
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of MAPK cascade
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
positive regulation of stress fiber assembly
cell chemotaxis
positive regulation of dendritic spine development
cellular response to oxygen levels
positive regulation of smooth muscle cell chemotaxis
cellular response to 1-oleoyl-sn-glycerol 3-phosphate
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support