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Product Details
CL488-68148
Product Specifications
Species Reactivity
Human,
Pig,
Rabbit
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1G7C6
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: GLLDAYLKTR TFLVGERVTL ADITVVCTLL WLYKQVLEPS FRQAFPNTNR WFLTCINQPQ FRAVLGEVKL CEKMAQFDAK KFAETQPKKD TPRKEKGSRE EKQKPQAERK EEKKAAAPAP EEEMDECEQA LAAEPKAKDP FAHLPKSTFV LDEFKRKYSN EDTLSVALPY FWEHFDKDGW SLWYSEYRFP EELTQTFMSC NLITGMFQRL DKLRKNAFAS VILFGTNNSS SISGVWVFRG QELAFPLSPD WQVDYESYTW R
Target Information
EF-1 (elongation factor-1) is a multi-protein complex that is responsible for the delivery of aminoacyl-tRNAs to the ribosome. EF-1 gamma (elongation factor- 1 gamma), also known as EEF1G or GIG35, is a 437 amino acid subunit of the EF-1 complex. Expressed in stomach, pancreas, brain, lung, kidney, intestine, liver and spleen, EF-1 gamma contains an N-terminal Glutathione transferase domain which is thought to be involved in anchoring the complex to various cellular components. Additionally, EF-1 gamma may play a key role in the assembly of multiprotein complexes containing aminoacyl-tRNA synthetases. Increased expression of EF-1 gamma is associated with pancreatic cancer, suggesting a possible role for EF-1 gamma in the oncogenic transformation process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eEF-1B gamma; EF-1-gamma; elongation factor 1 gamma; Elongation factor 1-gamma; pancreatic tumor-related protein; PRO1608; translation elongation factor eEF-1 gamma chain
Gene Aliases: eEF-1 gamma; EEF1G; EF1G; GIG35; PRO1608
UniProt ID: (Human) P26641, (Rabbit) P29694
Entrez Gene ID: (Human) 1937, (Rabbit) 100009282, (Pig) 397022
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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