Proteintech

EFTUD2 Polyclonal Antibody

EFTUD2 Antibody in Immunocytochemistry (ICC/IF)

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EFTUD2 Antibody (10208-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using EFTUD2 antibody 10208-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

EFTUD2 Antibody in Immunoprecipitation (IP)

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Product Details

10208-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 10 publications 10 publications

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

in situ PLA (PLA)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

EFTUD2 Fusion Protein Ag0279 (13-217 aa encoded by BC002360)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

10208-1-AP is a rabbit polyclonal antibody raised against the N-terminal of human EFTUD2.

Immunogen sequence: IGPELDSDE DDDELGRETK DLDEMDDDDD DDDVGDHDDD HPGMEVVLHE DKKYYPTAEE VYGPEVETIV QEEDTQPLTE PIIKPVKTKK FTLMEQTLPV TVYEMDFLAD LMDNSELIRN VTLCGHLHHG KTCFVDCLIE QTHPEIRKRY DQDLCYTDIL FTEQERGVGI KSTPVTVVLP DTKGKSYLFN IMDTPGHVNF SDEVTA (13-217 aa encoded by BC002360)

Target Information

EFTUD2 is component of the U5 snRNP complex required for pre-mRNA splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells.

iScience

Yu NK,McClatchy DB,Diedrich JK,Romero S,Choi JH,Martínez-Bartolomé S,Delahunty CM,Muotri AR,Yates JR

Fri Nov 19 00:00:00 UTC 2021

Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells.

iScience

Yu NK,McClatchy DB,Diedrich JK,Romero S,Choi JH,Martínez-Bartolomé S,Delahunty CM,Muotri AR,Yates JR

Fri Nov 19 00:00:00 UTC 2021

Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40.

Nature immunology

Zhang D,Yue T,Choi JH,Nair-Gill E,Zhong X,Wang KW,Zhan X,Li X,Choi M,Tang M,Quan J,Hildebrand S,Moresco EMY,Beutler B

Tue Oct 01 00:00:00 UTC 2019

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.

RNA (New York, N.Y.)

Jiao AL,Perales R,Umbreit NT,Haswell JR,Piper ME,Adams BD,Pellman D,Kennedy S,Slack FJ

Fri Mar 01 00:00:00 UTC 2019

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor.

RNA (New York, N.Y.)

Jiao AL,Perales R,Umbreit NT,Haswell JR,Piper ME,Adams BD,Pellman D,Kennedy S,Slack FJ

Fri Mar 01 00:00:00 UTC 2019

XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence.

Nucleic acids research

Hou S,Qu D,Li Y,Zhu B,Liang D,Wei X,Tang W,Zhang Q,Hao J,Guo W,Wang W,Zhao S,Wang Q,Azam S,Khan M,Zhao H,Zhang L,Lei H

Thu Sep 05 00:00:00 UTC 2019

Reduced prostaglandin I₂ signaling in Arid5b^-/- primary skeletal muscle cells attenuates myogenesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Murray J,Whitson RH,Itakura K

Sun Apr 01 00:00:00 UTC 2018

Reduced prostaglandin I₂ signaling in Arid5b^-/- primary skeletal muscle cells attenuates myogenesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Murray J,Whitson RH,Itakura K

Sun Apr 01 00:00:00 UTC 2018

Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.

The Journal of biological chemistry

Chen Z,Gui B,Zhang Y,Xie G,Li W,Liu S,Xu B,Wu C,He L,Yang J,Yi X,Yang X,Sun L,Liang J,Shang Y

Fri Nov 03 00:00:00 UTC 2017

Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.

The Journal of biological chemistry

Chen Z,Gui B,Zhang Y,Xie G,Li W,Liu S,Xu B,Wu C,He L,Yang J,Yi X,Yang X,Sun L,Liang J,Shang Y

Fri Nov 03 00:00:00 UTC 2017

Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.

The Journal of biological chemistry

Chen Z,Gui B,Zhang Y,Xie G,Li W,Liu S,Xu B,Wu C,He L,Yang J,Yi X,Yang X,Sun L,Liang J,Shang Y

Fri Nov 03 00:00:00 UTC 2017

Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.

The Journal of biological chemistry

Chen Z,Gui B,Zhang Y,Xie G,Li W,Liu S,Xu B,Wu C,He L,Yang J,Yi X,Yang X,Sun L,Liang J,Shang Y

Fri Nov 03 00:00:00 UTC 2017

Proteomic characterization of the nucleolar linker histone H1 interaction network.

Journal of molecular biology

Szerlong HJ,Herman JA,Krause CM,DeLuca JG,Skoultchi A,Winger QA,Prenni JE,Hansen JC

Fri Jun 05 00:00:00 UTC 2015

Proteomic characterization of the nucleolar linker histone H1 interaction network.

Journal of molecular biology

Szerlong HJ,Herman JA,Krause CM,DeLuca JG,Skoultchi A,Winger QA,Prenni JE,Hansen JC

Fri Jun 05 00:00:00 UTC 2015

A proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groups.

Proteomics

Jang MK,Anderson DE,van Doorslaer K,McBride AA

Mon Jun 01 00:00:00 UTC 2015

A proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groups.

Proteomics

Jang MK,Anderson DE,van Doorslaer K,McBride AA

Mon Jun 01 00:00:00 UTC 2015

Knockdown of AT-rich interaction domain (ARID) 5B gene expression induced AMPKα2 activation in cardiac myocytes.

Bioscience trends

Hirose-Yotsuya L,Okamoto F,Yamakawa T,Whitson RH,Fujita-Yamaguchi Y,Itakura K

Tue Dec 01 00:00:00 UTC 2015

A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.

Molecular and cellular biology

Berg MG,Wan L,Younis I,Diem MD,Soo M,Wang C,Dreyfuss G

Sun Apr 01 00:00:00 UTC 2012

A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.

Molecular and cellular biology

Berg MG,Wan L,Younis I,Diem MD,Soo M,Wang C,Dreyfuss G

Sun Apr 01 00:00:00 UTC 2012

New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.

Proteomics. Clinical applications

Huang R,Yu M,Li CY,Zhan YQ,Xu WX,Xu F,Ge CH,Li W,Yang XM

Mon Oct 01 00:00:00 UTC 2012

New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells.

Proteomics. Clinical applications

Huang R,Yu M,Li CY,Zhan YQ,Xu WX,Xu F,Ge CH,Li W,Yang XM

Mon Oct 01 00:00:00 UTC 2012

American journal of physiology. Cell physiology

Murray J,Huss JM

Thu Sep 01 00:00:00 UTC 2011

American journal of physiology. Cell physiology

Murray J,Huss JM

Thu Sep 01 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: 116 kDa U5 small nuclear ribonucleoprotein component; Elongation factor Tu GTP-binding domain-containing protein 2; hSNU114; SNU114 homolog; U5 small nuclear ribonucleoprotein 116 kDa; U5 snRNP-specific protein, 116 kDa; U5-116 kDa

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Gene Aliases: 116kDa; EFTUD2; KIAA0031; MFDGA; MFDM; SNRNP116; SNRP116; Snu114; U5-116KD

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UniProt ID: (Human) Q15029, (Mouse) O08810

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Entrez Gene ID: (Human) 9343, (Rat) 287739, (Mouse) 20624

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Function(s)

GTPase activity protein binding GTP binding poly(A) RNA binding nucleotide binding

Process(es)

metabolic process mRNA splicing, via spliceosome mRNA processing translation RNA splicing cellular response to drug response to cocaine

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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EFTUD2 Polyclonal Antibody

EFTUD2 Antibody (10208-1-AP) in ICC/IF

Product Details

10208-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

in situ PLA (PLA)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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