Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
EGR4 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
EGR4 Antibody (PA5-116975) in WB
Western blot analysis of EGR4 in mouse brain. Samples were incubated with EGR4 Polyclonal antibody (Product # PA5-116975) followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product Details
PA5-116975
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 440-589 of human EGR4 (NP_0019563)
Conjugate
Form
Liquid
Concentration
1.42 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901605
Product Specific Information
Positive Samples: Mouse brain
Immunogen sequence: GVAAPPVPPP PPTPFPQAKA RRKGRRGGKC STRCFCPRPH AKAFACPVES CVRSFARSDE LNRHLRIHTG HKPFQCRICL RNFSRSDHLT THVRTHTGEK PFACDVCGRR FARSDEKKRH SKVHLKQKAR AEERLKGLGF YSLGLSFASL
Target Information
Early growth response protein 4 (EGR-4), also known as AT133, is a protein that in humans is encoded by the EGR4 gene. EGR-4 is a member of the early growth response (EGF) family of zinc finger transcription factors. Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: AT133; Early growth response protein 4; Early response protein NGFI-C; EGR-4; Nerve growth factor-induced protein C; NGFI-C; zinc-finger transcription factor NGFI-C (early response gene)
Gene Aliases: Egr-4; EGR4; Egr4l1; NGF1-C; NGFI-C; NGFIC; PAT133
UniProt ID: (Human) Q05215, (Rat) Q00911, (Mouse) Q9WUF2
Entrez Gene ID: (Human) 1961, (Rat) 25129, (Mouse) 13656
transcription, DNA-templated
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
cellular response to cAMP
cellular response to growth factor stimulus
cellular response to gonadotropin stimulus
regulation of transcription, DNA-templated
positive regulation of cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support