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Invitrogen
EHMT2 Monoclonal Antibody (2D12A11)
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FIGURE: 1 / 7
EHMT2 Antibody (MA5-38514) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of EHMT2 in HeLa cells using EHMT2 Monoclonal Antibody (Product # MA5-38514) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Product # 35503)
Product Details
MA5-38514
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2D12A11
Immunogen
Purified recombinant fragment of human EHMT2 (aa: 317-471) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2898427
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ankyrin repeat-containing protein; DKFZp686H08213; Euchromatic histone-lysine N-methyltransferase 2; FLJ35547; G9A histone methyltransferase; H3 ly; H3-K9-Histone-Methyl-Transferase; H3-K9-HMTase 3; Histone H3-K9 methyltransferase 3; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; HLA-B associated transcript 8; HLA-B-associated transcript 8; Lysine N-methyltransferase 1C; NG36/G9a; Protein G9a
Gene Aliases: BAT8; C6orf30; EHMT2; G9A; GAT8; KMT1C; NG36
UniProt ID: (Human) Q96KQ7
Entrez Gene ID: (Human) 10919
p53 binding
protein binding
zinc ion binding
protein-lysine N-methyltransferase activity
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K9 specific)
histone methyltransferase activity (H3-K27 specific)
C2H2 zinc finger domain binding
promoter-specific chromatin binding
negative regulation of transcription from RNA polymerase II promoter
regulation of DNA replication
DNA methylation
cellular response to starvation
histone methylation
peptidyl-lysine dimethylation
histone lysine methylation
histone H3-K9 methylation
histone H3-K27 methylation
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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