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          • Primary Antibodies ›
          • eIF2b gamma Antibodies

          OriGene

          EIF2B3 Monoclonal Antibody (OTI1D6), TrueMAB™

          View all (21) eIF2b gamma antibodies

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          Cite EIF2B3 Monoclonal Antibody (OTI1D6), TrueMAB™

          • Antibody Testing Data (5)
          EIF2B3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          EIF2B3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 5

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          EIF2B3 Antibody (TA503630) in IHC (P)

          Immunohistochemical staining of paraffin-embedded human endometrium tissue within the normal limits using anti-EIF2B3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503630) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          EIF2B3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EIF2B3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EIF2B3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EIF2B3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          EIF2B3 Antibody in Western Blot (WB)

          Product Details

          TA503630

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:150
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG2b

          Class

          Monoclonal

          Type

          Antibody

          Clone

          OTI1D6

          Immunogen

          Full length human recombinant protein of human EIF2B3 produced in HEK293T cell.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.2 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS with 1% BSA, 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: eIF-2B GDP-GTP exchange factor subunit gamma; eIF2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; Translation initiation factor eIF2B subunit gamma

          View more View less

          Gene Aliases: EIF-2B; EIF2B3; EIF2Bgamma

          View more View less

          UniProt ID: (Human) Q9NR50

          View more View less

          Entrez Gene ID: (Human) 8891

          View more View less

          Function(s)
          translation initiation factor activity guanyl-nucleotide exchange factor activity protein binding translation factor activity, RNA binding nucleotidyltransferase activity
          Process(es)
          translational initiation response to heat response to glucose oligodendrocyte development negative regulation of translational initiation in response to stress response to peptide hormone positive regulation of GTPase activity cellular response to stimulus
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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