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Proteintech
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Immunogen sequence: MAASAKKKN KKGKTISLTD FLAEDGGTGG GSTYVSKPVS WADETDDLEG DVSTTWHSND DDVYRAPPID RSILPTAPRA AREPNIDRSR LPKSPPYTAF LGNLPYDVTE ESIKEFFRGL NISAVRLPRE PSNPERLKGF GYAEFEDLDS LLSALSLNEE SLGNRRIRVD VADQAQDKDR DDRSFGRDRN RDSDKTDTDW RARPATDSFD DYPPRRGDDS FGDKYRDRYD SDRYRDGYRD GYRDGPRRDM DRYGGRDRYD DRGSRDYDRG YDSRIGSGRR AFGSGYRRDD DYRGGGDRYE DRYDRRDDRS WSSRDDYSRD DYRRDDRGPP QRPKLNLKPR STPKEDDSSA S (1-350 aa encoded by BC073154)
The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609
Gene Aliases: 2310046H11Rik; AL024095; C85189; EIF-4B; Eif4a2; EIF4B; PRO1843
UniProt ID: (Human) P23588, (Mouse) Q8BGD9
Entrez Gene ID: (Human) 1975, (Rat) 300253, (Mouse) 75705
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