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EIF4E3 Polyclonal Antibody

EIF4E3 Antibody in Immunocytochemistry (ICC/IF)

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EIF4E3 Antibody (17282-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using EIF4E3 antibody 17282-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

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Product Details

17282-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

1:10-1:100

View 2 publications 2 publications

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

EIF4E3 Fusion Protein Ag11056 (1-118 aa encoded by BC031289)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MRGERRPLW EEESNAKGGV WKMKVPKDST STVWKELLLA TIGEQFTDCA AADDEVIGVS VSVRDREDVV QVWNVNASLV GEATVLEKIY ELLPHITFKA VFYKPHEEHH AFEGGRGKH (1-118 aa encoded by BC031289 )

Target Information

EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

N7-methylguanosin regulators-mediated methylation modification patterns and characterization of the immune microenvironment in lower-grade glioma.

European journal of medical research

Maimaiti A,Feng Z,Liu Y,Turhon M,Xie Z,Baihetiyaer Y,Wang X,Kasimu M,Jiang L,Wang Y,Wang Z,Pei Y

Thu Mar 30 00:00:00 UTC 2023

N7-methylguanosin regulators-mediated methylation modification patterns and characterization of the immune microenvironment in lower-grade glioma.

European journal of medical research

Maimaiti A,Feng Z,Liu Y,Turhon M,Xie Z,Baihetiyaer Y,Wang X,Kasimu M,Jiang L,Wang Y,Wang Z,Pei Y

Thu Mar 30 00:00:00 UTC 2023

Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix.

iScience

Shaiken TE,Grimm SL,Siam M,Williams A,Rezaeian AH,Kraushaar D,Ricco E,Robertson MJ,Coarfa C,Jain A,Malovannaya A,Stossi F,Opekun AR,Price AP,Dubrulle J

Fri Feb 17 00:00:00 UTC 2023

RNA m⁶A methylation regulates dissemination of cancer cells by modulating expression and membrane localization of β-catenin.

Molecular therapy : the journal of the American Society of Gene Therapy

Li J,Xie G,Tian Y,Li W,Wu Y,Chen F,Lin Y,Lin X,Wing-Ngor Au S,Cao J,He W,Wang H

Wed Apr 06 00:00:00 UTC 2022

Local translation in nuclear condensate amyloid bodies.

Proceedings of the National Academy of Sciences of the United States of America

Theodoridis PR,Bokros M,Marijan D,Balukoff NC,Wang D,Kirk CC,Budine TD,Goldsmith HD,Wang M,Audas TE,Lee S

Tue Feb 16 00:00:00 UTC 2021

The Effect of MicroRNA-101 on Angiogenesis of Human Umbilical Vein Endothelial Cells during Hypoxia and in Mice with Myocardial Infarction.

BioMed research international

Pang J,Ye L,Chen Q,Wang J,Yang X,He W,Hao L

Thu Apr 29 00:00:00 UTC 2021

Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice.

Biology of reproduction

Hu J,Sun F,Handel MA

Mon Jan 01 00:00:00 UTC 2018

Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice.

Biology of reproduction

Hu J,Sun F,Handel MA

Mon Jan 01 00:00:00 UTC 2018

MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma.

Nature communications

Abdelfattah N,Rajamanickam S,Panneerdoss S,Timilsina S,Yadav P,Onyeagucha BC,Garcia M,Vadlamudi R,Chen Y,Brenner A,Houghton P,Rao MK

Wed Oct 31 00:00:00 UTC 2018

MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma.

Nature communications

Abdelfattah N,Rajamanickam S,Panneerdoss S,Timilsina S,Yadav P,Onyeagucha BC,Garcia M,Vadlamudi R,Chen Y,Brenner A,Houghton P,Rao MK

Wed Oct 31 00:00:00 UTC 2018

MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma.

Nature communications

Abdelfattah N,Rajamanickam S,Panneerdoss S,Timilsina S,Yadav P,Onyeagucha BC,Garcia M,Vadlamudi R,Chen Y,Brenner A,Houghton P,Rao MK

Wed Oct 31 00:00:00 UTC 2018

MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma.

Nature communications

Abdelfattah N,Rajamanickam S,Panneerdoss S,Timilsina S,Yadav P,Onyeagucha BC,Garcia M,Vadlamudi R,Chen Y,Brenner A,Houghton P,Rao MK

Wed Oct 31 00:00:00 UTC 2018

Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming.

Oncotarget

Riz I,Hawley TS,Marsal JW,Hawley RG

Tue Oct 11 00:00:00 UTC 2016

Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming.

Oncotarget

Riz I,Hawley TS,Marsal JW,Hawley RG

Tue Oct 11 00:00:00 UTC 2016

MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.

Nature communications

Landon AL,Muniandy PA,Shetty AC,Lehrmann E,Volpon L,Houng S,Zhang Y,Dai B,Peroutka R,Mazan-Mamczarz K,Steinhardt J,Mahurkar A,Becker KG,Borden KL,Gartenhaus RB

Tue Nov 18 00:00:00 UTC 2014

MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.

Nature communications

Landon AL,Muniandy PA,Shetty AC,Lehrmann E,Volpon L,Houng S,Zhang Y,Dai B,Peroutka R,Mazan-Mamczarz K,Steinhardt J,Mahurkar A,Becker KG,Borden KL,Gartenhaus RB

Tue Nov 18 00:00:00 UTC 2014

MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.

Nature communications

Landon AL,Muniandy PA,Shetty AC,Lehrmann E,Volpon L,Houng S,Zhang Y,Dai B,Peroutka R,Mazan-Mamczarz K,Steinhardt J,Mahurkar A,Becker KG,Borden KL,Gartenhaus RB

Tue Nov 18 00:00:00 UTC 2014

MNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.

Nature communications

Landon AL,Muniandy PA,Shetty AC,Lehrmann E,Volpon L,Houng S,Zhang Y,Dai B,Peroutka R,Mazan-Mamczarz K,Steinhardt J,Mahurkar A,Becker KG,Borden KL,Gartenhaus RB

Tue Nov 18 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: eIF-4E type 3; eIF-4E3; eIF4E type 3; eukaryotic translation initiation factor 4E member 3; Eukaryotic translation initiation factor 4E type 3; eukaryotic translation initiation factor-3

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Gene Aliases: 1300018P11Rik; AI451927; eIF-4E3; eIF4E-3; EIF4E3

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UniProt ID: (Human) Q8N5X7, (Mouse) Q9DBB5

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Entrez Gene ID: (Human) 317649, (Rat) 297481, (Mouse) 66892

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Function(s)

translation initiation factor activity molecular_function RNA binding

Process(es)

translational initiation regulation of translation translation biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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EIF4E3 Polyclonal Antibody

EIF4E3 Antibody (17282-1-AP) in ICC/IF

Product Details

17282-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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